Results 41 to 50 of about 2,739,032 (319)

Interactions between Tryptophan Metabolism, the Gut Microbiome and the Immune System as Potential Drivers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Metabolic Diseases

, 2022
The prevalence of non-alcoholic fatty liver disease (NAFLD) is increasing and therefore is its burden of disease as NALFD is a risk factor for cirrhosis and is associated with other metabolic conditions such as type II diabetes, obesity, dyslipidaemia ...
Max Nieuwdorp, Nieuwdorp, Max, Teunis, Charlotte, Hanssen, Nordin, Charlotte Teunis, Nordin Hanssen   +5 more
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Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
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PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells

International Journal of Endocrinology, 2023
Background. Patatin-like phospholipase domain-containing 3 (PNPLA3) is a major susceptibility gene for nonalcoholic fatty liver disease (NAFLD), and its rs738409 (I148M) polymorphism is associated with the occurrence and progression of NAFLD. Endoplasmic
Yunzhi Chen, Xuemei Yan, Tian Wang, Hongrong Deng, Xiaojie Deng, Fen Xu, Hua Liang   +6 more
doaj   +1 more source

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J., Schwaiger, Markus, Drzezga, A., Hampel, H., Bokde, ALW, Leinsinger, G., Born, C., Thissen, J., Bartenstein, P., Dong, W., Schwaiger, M., Möller, Hans-Jürgen   +11 more
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The Effect of Liraglutide on Epicardial Adipose Tissue in Type 2 Diabetes

Journal of Diabetes Research, 2021
Objective. To study the effect of liraglutide on the thickness of epicardial adipose tissue (EAT) in type 2 diabetes mellitus (T2DM) patients with abdominal obesity. Methods.
Na Zhao, Xiaoying Wang, Yongbo Wang, Junjie Yao, Chunhong Shi, Jianling Du, Ran Bai   +6 more
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Identification and Functional Characterization of a Novel Variant in the SEMA3A Gene in a Chinese Family with Kallmann Syndrome

International Journal of Endocrinology, 2022
Background. Kallmann syndrome (KS) is a rare genetic disease characterized by the reproductive system and olfactory dysplasia due to the defective migration of gonadotropin-releasing hormone (GnRH) neurons.
Meng Shu, Huixiao Wu, Shuoshuo Wei, Yingzhou Shi, Zongyue Li, Yiping Cheng, Li Fang, Chao Xu   +7 more
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Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification

Mediators of Inflammation, 2022
Inflammation and fibrosis are the important pathophysiologic processes in diabetic kidney disease (DKD), which is induced by epigenetics, especially histone posttranslational modification (HPTMs).
Tingting Zhou, Huiwen Xu, Xi Cheng, Yanqiu He, Qian Ren, Dongzhe Li, Yumei Xie, Chenlin Gao, Yuanyuan Zhang, Xiaodong Sun, Yong Xu, Wei Huang   +11 more
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Ovarian Cancer and Glutamine Metabolism

, 2023
Cancer cells are known to have a distinct metabolic profile and to exhibit significant changes in a variety of metabolic mechanisms compared to normal cells, particularly glycolysis and glutaminolysis, in order to cover their increased energy ...
Athanasios Chionis, Konstantinos Nikolettos, Zacharias Fasoulakis, Sotirios Sotiriou, Ioannis Prokopakis, Antonios Koutras, Alexandros Katrachouras, Athina A. Samara, Ioakeim Sapantzoglou, Paraskevas Perros, Asimina Valsamaki, Panos Antsaklis, Marianna Theodora, Kyriakos Konis, Athanasios Pagkalos, Thomas Ntounis, Vasileios-Chrysovalantis Palios, Georgios Daskalakis, Emmanuel N. Kontomanolis, Panagiotis Symeonidis   +19 more
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GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism [PDF]

, 2019
Lipoprotein lipase (LPL), identified in the 1950s, has been studied intensively by biochemists, physiologists, and clinical investigators. These efforts uncovered a central role for LPL in plasma triglyceride metabolism and identified LPL mutations as a ...
He, Cuiwen, Jiang, Haibo, Allan, Christopher M., Fong, Loren G, Birrane, Gabriel, Ploug, Michael, Allan, Christopher M, Young, Stephen G, Meiyappan, Muthuraman, Beigneux, Anne P, Fong, Loren G., Young, Stephen G., Beigneux, Anne P., Nakajima, Katsuyuki   +13 more
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Endoscopic Delivery Method Using a Retrieval Net for Patients with Small-Bowel Capsule Endoscopy Stagnation in the Stomach

Gastroenterology Research and Practice, 2021
With the increasing use of capsule endoscopy (CE), screening tests for the small bowel can be performed with minimal invasiveness. However, occasionally, the entire small bowel cannot be observed because of decreased peristalsis of the stomach.
Akihiko Sumioka, Shiro Oka, Akiyoshi Tsuboi, Issei Hirata, Sumio Iio, Hidenori Tanaka, Ken Yamashita, Takahiro Kotachi, Ryo Yuge, Yuji Urabe, Shinji Tanaka   +10 more
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