Results 21 to 30 of about 2,739,032 (319)

Investigation of early-diverging land plant metabolism

, 2022
The terrestrialisation of embryophytes was preceded by, and precipitated, the evolution of diverse metabolic capabilities to aid growth and survival on land.
Cannell, Naomi
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Low Serum Total Testosterone Is Associated with Non-Alcoholic Fatty Liver Disease in Men but Not in Women with Type 2 Diabetes Mellitus

International Journal of Endocrinology, 2022
Aims/Introduction. Sex steroid hormones play a significant role in the progression of cardiovascular and metabolic diseases, including non-alcoholic fatty liver disease (NAFLD).
Xinxin Zhang, Jinfeng Xiao, Qi Liu, Yuanyuan Ye, Weihong Guo, Jingqiu Cui, Qing He, Wenli Feng, Ming Liu   +8 more
doaj   +1 more source

Caveolin-1 Is Essential for the Improvement of Insulin Sensitivity through AKT Activation during Glargine Treatment on Diabetic Mice

Journal of Diabetes Research, 2021
Insulin treatment was confirmed to reduce insulin resistance, but the underlying mechanism remains unknown. Caveolin-1 (Cav-1) is a functional protein of the membrane lipid rafts, known as caveolae, and is widely expressed in mammalian adipose tissue ...
Hangya Peng, Panwei Mu, Haicheng Li, Shuo Lin, Chuwen Lin, Keyi Lin, Kunying Liu, Wen Zeng, Longyi Zeng   +8 more
doaj   +1 more source

Fructose metabolism and metabolic disease [PDF]

Journal of Clinical Investigation, 2018
Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful.
Herman, Mark A, Hannou, Sarah A, McKeown, Nicola M, Haslam, Danielle E   +3 more
openaire   +2 more sources

Steroidogenic control of liver metabolism through a nuclear receptor-network [PDF]

, 2019
OBJECTIVE: Coupling metabolic and reproductive pathways is essential for the survival of species. However, the functions of steroidogenic enzymes expressed in metabolic tissues are largely unknown.
Owen, Bryn M., Burgering, Boudewijn M.T., Massafra, Vittoria, Williamson, Catherine, Owen, Bryn M, Burgering, Boudewijn MT, van Mil, Saskia W.C., Vernia, Santiago, Paterson, Helen AB, Bosma, Piter, Willemsen, Ellen C. L., van Mil, Saskia W. C., van Mil, Saskia WC, Burgering, Boudewijn M. T., Ramos Pittol, Jose M, Bijsmans, Ingrid T.G.W., Artigas, Natalia, Bijsmans, Ingrid TGW, Willemsen, Ellen CL, Dhillo, Waljit S., Milona, Alexandra, Naik, Jyoti, Vos, Harmjan, Paterson, Helen A. B., Bijsmans, Ingrid T. G. W., Willemsen, Ellen C.L., Miguel-Aliaga, Irene, Ramos Pittol, Jose M., Paterson, Helen A.B., Dhillo, Waljit S   +29 more
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MicroRNAs in Metabolism and Metabolic Diseases [PDF]

Cold Spring Harbor Symposia on Quantitative Biology, 2011
Aberrant cholesterol/lipid homeostasis is linked to a number of diseases prevalent in the developed world, including metabolic syndrome, type II diabetes, and cardiovascular disease. We have previously uncovered gene regulatory mechanisms of the sterol regulatory element-binding protein (SREBP) family of transcription factors, which control the ...
V, Rottiers, S H, Najafi-Shoushtari, F, Kristo, S, Gurumurthy, L, Zhong, Y, Li, D E, Cohen, R E, Gerszten, N, Bardeesy, R, Mostoslavsky, A M, Näär   +10 more
openaire   +2 more sources

Chapter 11: The approach to achieving glycaemic control

South African Family Practice, 2018
Type 2 diabetes is a heterogeneous disease, with the underlying mechanism ranging from predominantly insulin resistance with relative insulin deficiency, to predominantly an insulin secretory defect with lesser degrees of insulin resistance. The relative
The Society for Endocrinology Metabolism and Diabetes of South Africa
doaj   +1 more source

Adrenal Hemorrhage in Patients with Systemic Lupus Erythematosus and Antiphospholipid Syndrome: A Case Report and Literature Review

International Journal of Endocrinology, 2023
Antiphospholipid syndrome (APS) is an autoimmune disorder while adrenal hemorrhage could be its rare complication. Herein, we report the case of a 32-year-old unmarried woman with a history of systemic lupus erythematosus (SLE) who was hospitalized after
Weiwei Jiang, Danrui Chen, Daizhi Yang, Longyi Zeng, Wen Xu, Shuo Lin   +5 more
doaj   +1 more source

Chapter 10: Glucose control: insulin therapy

South African Family Practice, 2018
Insulin and its analogues lower blood glucose by stimulating peripheral glucose uptake, especially by skeletal muscle and fat, and by inhibiting hepatic glucose production. Insulin inhibits lipolysis and proteolysis, and enhances protein synthesis.
The Society for Endocrinology Metabolism and Diabetes of South Africa
doaj   +1 more source

Maternal nutritional status, C1 metabolism and offspring DNA methylation: a review of current evidence in human subjects. [PDF]

, 2011
: Evidence is growing for the long-term effects of environmental factors during early-life on later disease susceptibility. It is believed that epigenetic mechanisms (changes in gene function not mediated by DNA sequence alteration), particularly DNA ...
Dominguez Salas, Paula, Dominguez-Salas, P, Prentice, AM, Sophie E. Moore, Cox, SE, Dominguez-Salas, Paula, Prentice, Andrew M, Hennig, Branwen J, Paula Dominguez-Salas, Andrew M. Prentice, Moore, SE, Moore, Sophie E, Hennig, BJ, Cox, Sharon E, Prentice, Andrew M., Moore, Sophie E., Hennig, Branwen J., Branwen J. Hennig, Sharon E. Cox, Cox, Sharon E.   +19 more
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