Results 11 to 20 of about 3,023,997 (318)
Essays in Biochemistry, 2020 Abstract Metabolism consists of a series of reactions that occur within cells of living organisms to sustain life. The process of metabolism involves many interconnected cellular pathways to ultimately provide cells with the energy required to carry out their function.
Ayesha Judge, Michael S. Dodd
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Quantifying redox metabolism in the plant metabolic network [PDF]
, 2022 The aim of this thesis was to develop and evaluate methods for quantifying redox metabolism in plants. Current methods suffer from a lack of: quantitative measurement; specificity between different redox carriers; and subcellular resolution.
Smith, Edward
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Investigation of early-diverging land plant metabolism [PDF]
, 2022 The terrestrialisation of embryophytes was preceded by, and precipitated, the evolution of diverse metabolic capabilities to aid growth and survival on land.
Cannell, Naomi
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Glucocorticoids, metabolism and metabolic diseases [PDF]
Molecular and Cellular Endocrinology, 2007 Since the discovery of the beneficial effects of adrenocortical extracts for treating adrenal insufficiency more than 80 years ago, glucocorticoids (GC) and their cognate, intracellular receptor, the glucocorticoid receptor (GR) have been characterized as critical components of the delicate hormonal control system that determines energy homeostasis in ...
Vegiopoulos, Alexandros, Herzig, Stephan
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NAD+ Metabolism, Metabolic Stress, and Infection [PDF]
Frontiers in Molecular Biosciences, 2021 Nicotinamide adenine dinucleotide (NAD+) is an essential metabolite with wide-ranging and significant roles in the cell. Defects in NAD+ metabolism have been associated with many human disorders; it is therefore an emerging therapeutic target. Moreover, NAD+ metabolism is perturbed during colonization by a variety of pathogens, either due to the ...
Groth, Benjamin +2 more
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Fructose Metabolism and Cardiac Metabolic Stress [PDF]
Frontiers in Pharmacology, 2021 Cardiovascular disease is one of the leading causes of mortality in diabetes. High fructose consumption has been linked with the development of diabetes and cardiovascular disease. Serum and cardiac tissue fructose levels are elevated in diabetic patients, and cardiac production of fructose via the intracellular polyol pathway is upregulated.
M. Annandale +11 more
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MicroRNAs in metabolism and metabolic disorders [PDF]
Nature Reviews Molecular Cell Biology, 2012 MicroRNAs (miRNAs) have recently emerged as key regulators of metabolism. For example, miR-33a and miR-33b have a crucial role in controlling cholesterol and lipid metabolism in concert with their host genes, the sterol-regulatory element-binding protein (SREBP) transcription factors.
Veerle, Rottiers, Anders M, Näär
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Discovering signaling mechanisms governing metabolism and metabolic diseases with Drosophila [PDF]
, 2021 There has been rapid growth in the use of Drosophila and other invertebrate systems to dissect mechanisms governing metabolism. New assays and approaches to physiology have aligned with superlative genetic tools in fruit flies to provide a powerful ...
Tsao, Deborah D +6 more
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MicroRNAs in Metabolism and Metabolic Diseases [PDF]
Cold Spring Harbor Symposia on Quantitative Biology, 2011 Aberrant cholesterol/lipid homeostasis is linked to a number of diseases prevalent in the developed world, including metabolic syndrome, type II diabetes, and cardiovascular disease. We have previously uncovered gene regulatory mechanisms of the sterol regulatory element-binding protein (SREBP) family of transcription factors, which control the ...
V, Rottiers +10 more
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Fructose metabolism and metabolic disease [PDF]
Journal of Clinical Investigation, 2018 Increased sugar consumption is increasingly considered to be a contributor to the worldwide epidemics of obesity and diabetes and their associated cardiometabolic risks. As a result of its unique metabolic properties, the fructose component of sugar may be particularly harmful.
Herman, Mark A +3 more
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