Results 31 to 40 of about 3,023,997 (318)

Serum Tenascin-C and Alarin Levels Are Associated with Cardiovascular Diseases in Type 2 Diabetes Mellitus

International Journal of Endocrinology, 2022
Background. Tenascin-C (TNC), an extracellular matrix glycoprotein, is elevated in inflammatory and cardiovascular pathologies, whereas alarin, a novel orexigenic peptide, participates in insulin resistance and glycometabolism.
Mingming Li, Mengjiao Wu, Hua Zhu, Yulin Hua, Zijun Ma, Jiayi Yao, Bin Feng, Bimin Shi   +7 more
doaj   +1 more source

The Relationships among Plasma Fetuin-B, Thyroid Autoimmunity, and Fertilization Rate In Vitro Fertilization and Embryo Transfer

International Journal of Endocrinology, 2022
Objective. The objective of the study is to investigate the relationships between fetuin-B, thyroid autoimmunity (TAI), and pregnancy outcomes in women undergoing in vitro fertilization and embryo transfer (IVF-ET). Design, Patients, and Measurements. In
Rui Zhang, Feifei Cheng, Wei Cheng, Xin Wang, Binghan Zhang, Mingyuan Tian, Ke Li, Dongfang Liu   +7 more
doaj   +1 more source

Combination of GLP-1 Receptor Activation and Glucagon Blockage Promotes Pancreatic β-Cell Regeneration In Situ in Type 1 Diabetic Mice

Journal of Diabetes Research, 2021
Pancreatic β-cell neogenesis in vivo holds great promise for cell replacement therapy in diabetic patients, and discovering the relevant clinical therapeutic strategies would push it forward to clinical application.
Liangbiao Gu, Dandan Wang, Xiaona Cui, Tianjiao Wei, Kun Yang, Jin Yang, Rui Wei, Tianpei Hong   +7 more
doaj   +1 more source

Peroxisome Proliferator Activated Receptors and Lipoprotein Metabolism [PDF]

, 2008
Plasma lipoproteins are responsible for carrying triglycerides and cholesterol in the blood and ensuring their delivery to target organs. Regulation of lipoprotein metabolism takes place at numerous levels including via changes in gene transcription.
Kersten, A.H., Sander Kersten
core   +1 more source

PNPLA3 148M/M Is More Susceptible to Palmitic Acid-Induced Endoplasmic Reticulum Stress-Associated Apoptosis in HepG2 Cells

International Journal of Endocrinology, 2023
Background. Patatin-like phospholipase domain-containing 3 (PNPLA3) is a major susceptibility gene for nonalcoholic fatty liver disease (NAFLD), and its rs738409 (I148M) polymorphism is associated with the occurrence and progression of NAFLD. Endoplasmic
Yunzhi Chen, Xuemei Yan, Tian Wang, Hongrong Deng, Xiaojie Deng, Fen Xu, Hua Liang   +6 more
doaj   +1 more source

Identification and Functional Characterization of a Novel Variant in the SEMA3A Gene in a Chinese Family with Kallmann Syndrome

International Journal of Endocrinology, 2022
Background. Kallmann syndrome (KS) is a rare genetic disease characterized by the reproductive system and olfactory dysplasia due to the defective migration of gonadotropin-releasing hormone (GnRH) neurons.
Meng Shu, Huixiao Wu, Shuoshuo Wei, Yingzhou Shi, Zongyue Li, Yiping Cheng, Li Fang, Chao Xu   +7 more
doaj   +1 more source

Association between cognitive performance and cortical glucose metabolism in patients with mild Alzheimer's disease [PDF]

, 2005
Background: Neuronal and synaptic function in Alzheimer's disease (AD) is measured in vivo by glucose metabolism using positron emission tomography (PET). Objective: We hypothesized that neuronal activation as measured by PET is a more sensitive index of
Teipel, S. J., Schwaiger, Markus, Drzezga, A., Hampel, H., Bokde, ALW, Leinsinger, G., Born, C., Thissen, J., Bartenstein, P., Dong, W., Schwaiger, M., Möller, Hans-Jürgen, Bokde, AL;Teipel, SJ;Drzezga, A;Thissen, J;Bartenstein, P;Dong, W;Leinsinger, G;Born, C;Schwaiger, M;Moeller, HJ;Hampel, H, Bokde, A.L.W.;Teipel, S. J.;Drzezga, A.;Thissen, J.;Bartenstein, P.;Dong, W.;Leinsinger, G.;Born, C.;Schwaiger, M.;Moeller, H.-J.;Hampel, H.   +13 more
core   +1 more source

Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification

Mediators of Inflammation, 2022
Inflammation and fibrosis are the important pathophysiologic processes in diabetic kidney disease (DKD), which is induced by epigenetics, especially histone posttranslational modification (HPTMs).
Tingting Zhou, Huiwen Xu, Xi Cheng, Yanqiu He, Qian Ren, Dongzhe Li, Yumei Xie, Chenlin Gao, Yuanyuan Zhang, Xiaodong Sun, Yong Xu, Wei Huang   +11 more
doaj   +1 more source

Ovarian Cancer and Glutamine Metabolism

, 2023
Cancer cells are known to have a distinct metabolic profile and to exhibit significant changes in a variety of metabolic mechanisms compared to normal cells, particularly glycolysis and glutaminolysis, in order to cover their increased energy ...
Athanasios Chionis, Konstantinos Nikolettos, Zacharias Fasoulakis, Sotirios Sotiriou, Ioannis Prokopakis, Antonios Koutras, Alexandros Katrachouras, Athina A. Samara, Ioakeim Sapantzoglou, Paraskevas Perros, Asimina Valsamaki, Panos Antsaklis, Marianna Theodora, Kyriakos Konis, Athanasios Pagkalos, Thomas Ntounis, Vasileios-Chrysovalantis Palios, Georgios Daskalakis, Emmanuel N. Kontomanolis, Panagiotis Symeonidis   +19 more
core   +1 more source

GPIHBP1 and Lipoprotein Lipase, Partners in Plasma Triglyceride Metabolism [PDF]

, 2019
Lipoprotein lipase (LPL), identified in the 1950s, has been studied intensively by biochemists, physiologists, and clinical investigators. These efforts uncovered a central role for LPL in plasma triglyceride metabolism and identified LPL mutations as a ...
He, Cuiwen, Jiang, Haibo, Allan, Christopher M., Fong, Loren G, Birrane, Gabriel, Ploug, Michael, Allan, Christopher M, Young, Stephen G, Meiyappan, Muthuraman, Beigneux, Anne P, Fong, Loren G., Young, Stephen G., Beigneux, Anne P., Nakajima, Katsuyuki   +13 more
core   +1 more source