A six-metabolite signature characterizes metabolically unhealthy obesity and reveals hidden metabolic risk within metabolically healthy obesity. [PDF]
Front Endocrinol (Lausanne)Gao P +7 more
europepmc +1 more source
Advanced Science, EarlyView.ABSTRACT Current prostate cancer detection methods remain limited in non‐invasiveness and specificity, prompting interest in urinary biomarkers such as sarcosine. Here, we report a urine‐powered wearable platform for non‐invasive sarcosine detection as a proof‐of‐concept for decentralized early warning.
Jing Xu +10 more
wiley +1 more source
PMPIHGLL: predicting metabolite-protein interactions using dual hypergraph convolutional networks and large language models. [PDF]
Brief BioinformChen L, Jin Z, Shao Y, Zhou B.
europepmc +1 more source
Engineering Microbial Particles for Next‐Generation Biomedical Platforms
Advanced Science, EarlyView.Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li +7 more
wiley +1 more source
Secondhand smoke exposure during pregnancy: Nicotine metabolites in maternal urine and breast milk as biomarkers of infant birth weight and length, a cross-sectional study. [PDF]
Tob Induc DisKunno J +7 more
europepmc +1 more source
Advanced Science, EarlyView.Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang +3 more
wiley +1 more source
Metabolic Profiling Using Gas Chromatography-Mass Spectrometry and Optimization of Light-Emitting Diodes for Callus Induction in Patchouli "Tapak Tuan" (Pogostemon cablin Benth.). [PDF]
Rapid Commun Mass SpectromHarnelly E +4 more
europepmc +1 more source
Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing
Advanced Science, EarlyView.Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley +1 more source
Mechanistic Perspectives From Genomics and Pangenomics of Medicinal and Aromatic Plants: Linking Genome Architecture to Phytochemical Diversity. [PDF]
Int J GenomicsSaini H +10 more
europepmc +1 more source
Advanced Science, EarlyView.An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng +9 more
wiley +1 more source