Results 31 to 40 of about 985,469 (331)

Liquid chromatography coupled with time-of-flight and ion trap mass spectrometry for qualitative analysis of herbal medicines

Journal of Pharmaceutical Analysis, 2011
With the expansion of herbal medicine (HM) market, the issue on how to apply up-to-date analytical tools on qualitative analysis of HMs to assure their quality, safety and efficacy has been arousing great attention. Due to its inherent characteristics of
Xiao-Fei Chen, Hai-Tang Wu, Guang-Guo Tan, Zhen-Yu Zhu, Yi-Feng Chai   +4 more
doaj   +1 more source

Effect of carnosine synthesis precursors in the diet on jejunal metabolomic profiling and biochemical compounds in slow-growing Korat chicken

Poultry Science, 2023
: The slow-growing Korat chicken (KR) has been developed to provide an alternative breed for smallholder farmers in Thailand. Carnosine enrichment in the meat can distinguish KR from other chicken breeds.
Kasarat Promkhun, Chanadda Suwanvichanee, Nathawat Tanpol, Sasikan Katemala, Kanjana Thumanu, Wittawat Molee, Satoshi Kubota, Pekka Uimari, Amonrat Molee   +8 more
doaj   +1 more source

MetaboTools: A comprehensive toolbox for analysis of genome-scale metabolic models [PDF]

, 2016
Metabolomic data sets provide a direct read-out of cellular phenotypes and are increasingly generated to study biological questions. Our previous work revealed the potential of analyzing extracellular metabolomic data in the context of the metabolic ...
Aurich, Maike K., Fleming, Ronan M. T., Thiele, Ines   +2 more
core   +3 more sources

¹³C NMR metabolomics: applications at natural abundance. [PDF]

, 2014
(13)C NMR has many advantages for a metabolomics study, including a large spectral dispersion, narrow singlets at natural abundance, and a direct measure of the backbone structures of metabolites.
Clendinen, Chaevien, Edison, Arthur, Hahn, Daniel, Lee-McMullen, Brittany, Stupp, Gregory, Vandenborne, Krista, Walter, Glenn, Williams, Caroline   +7 more
core   +3 more sources

Isoflavones' effects on pharmacokinetic profiles of main iridoids from Gardeniae Fructus in rats

Journal of Pharmaceutical Analysis, 2020
Gardeniae Fructus (GF) and Semen Sojae Praeparatum (SSP) are both medicine food homologies and widely used in Chinese clinical prescriptions together. The research investigated the pharmacokinetics of four iridoids in normal rats and isolfavones-fed rats,
Ruirui Chang, Jialin Liu, Yusha Luo, Taohong Huang, Qiang Li, Jun Wen, Weidong Chen, Tingting Zhou   +7 more
doaj   +1 more source

High-Throughput Determination of Sodium Danshensu in Beagle Dogs by the LCMS/MS Method, Employing Liquid-Liquid Extraction Based on 96-Well Format Plates

Molecules, 2017
Sodium Danshensu (sodium d-(+)-β-(3,4-dihydroxyphenyl) lactate), one of the water-soluble ingredients in Salvia miltiorrhiza, exhibits potent relaxation of the coronary artery and anticoagulation effection.
Jingjing Jiang, Xin Zhao, Xiuxiu Li, Shengyuan Wu, Shidan Yu, Yuefen Lou, Guorong Fan   +6 more
doaj   +1 more source

Understanding and Classifying Metabolite Space and Metabolite-Likeness

PLoS ONE, 2011
While the entirety of 'Chemical Space' is huge (and assumed to contain between 10(63) and 10(200) 'small molecules'), distinct subsets of this space can nonetheless be defined according to certain structural parameters. An example of such a subspace is the chemical space spanned by endogenous metabolites, defined as 'naturally occurring' products of an
Peironcely, Miguel J.E., Reijmers, T.H., Coulier, L., Bender, A., Hankemeier, T.   +4 more
openaire   +6 more sources

Comprehensive metabolomic and lipidomic alterations in response to heat stress during seed germination and seedling growth of Arabidopsis

Frontiers in Plant Science, 2023
Temperature affects seed germination and seedling growth, which is a critical and complex stage in plant life cycle. However, comprehensive metabolic basis on temperature implicating seed germination and seedling growth remains less known.
Wenjuan Qian, Yuxuan Zhu, Qinsheng Chen, Shuaiyao Wang, Longlong Chen, Ting Liu, Huiru Tang, Hongyan Yao   +7 more
doaj   +1 more source

Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase [PDF]

, 2015
Background Statins are first-line therapy for cardiovascular disease prevention, but their systemic effects across lipoprotein subclasses, fatty acids, and circulating metabolites remain incompletely characterized.
Ala-Korpela, M, Casas, J-P, Chaturvedi, N, Fatemifar, G, Hingorani, AD, Hughes, AD, Jarvelin, M-R, Kahonen, M, Kangas, AJ, Kettunen, J, Kivimaki, M, Lawlor, DA, Lehtimaki, T, Mantyselka, P, Perola, M, Raitakari, OT, Salomaa, V, Sattar, N, Smith, GD, Soininen, P, Tiainen, M, Tillin, T, Tynkkynen, T, Vanhala, M, Wang, Q, Wurtz, P   +25 more
core   +2 more sources

Advances in sensor developments for cell culture monitoring

BMEMat, 2023
Cell culture encompasses procedures for extracting cells from their natural tissue and cultivating them under controlled artificial conditions. During this process, various factors, including cell physiological/morphological properties, culture ...
Ka Ram Kim, Woon‐Hong Yeo
doaj   +1 more source