Results 11 to 20 of about 2,167,847 (388)
Plant Secondary Metabolites: The Weapons for Biotic Stress Management
Metabolites, 2023 The rise in global temperature also favors the multiplication of pests and pathogens, which calls into question global food security. Plants have developed special coping mechanisms since they are sessile and lack an immune system. These mechanisms use a
J. M. Al-Khayri +11 more
semanticscholar +1 more source
Small molecule metabolites: discovery of biomarkers and therapeutic targets
Signal Transduction and Targeted Therapy, 2023 Metabolic abnormalities lead to the dysfunction of metabolic pathways and metabolite accumulation or deficiency which is well-recognized hallmarks of diseases. Metabolite signatures that have close proximity to subject’s phenotypic informative dimension,
Shi Qiu +6 more
semanticscholar +1 more source
Gut-Microbiota-Derived Metabolites Maintain Gut and Systemic Immune Homeostasis
Cells, 2023 The gut microbiota, including bacteria, archaea, fungi, viruses and phages, inhabits the gastrointestinal tract. This commensal microbiota can contribute to the regulation of host immune response and homeostasis.
Juanjuan Wang +4 more
semanticscholar +1 more source
Metabolism, metabolites, and macrophages in cancer
Journal of Hematology & Oncology, 2023 Tumour-associated macrophages (TAMs) are crucial components of the tumour microenvironment and play a significant role in tumour development and drug resistance by creating an immunosuppressive microenvironment.
Mengyuan Li +5 more
semanticscholar +1 more source
Life, 2023 Several environmental stresses, including biotic and abiotic factors, adversely affect the growth and development of crops, thereby lowering their yield.
Uzma Salam +7 more
semanticscholar +1 more source
Environmental Factors Regulate Plant Secondary Metabolites
Plants, 2023 Abiotic environmental stresses can alter plant metabolism, leading to inhibition or promotion of secondary metabolites. Although the crucial roles of these compounds in plant acclimation and defense are well known, their response to climate change is ...
M. Qaderi +2 more
semanticscholar +1 more source
Mitochondrial TCA cycle metabolites control physiology and disease
Nature Communications, 2020 Mitochondria are signaling organelles that regulate a wide variety of cellular functions and can dictate cell fate. Multiple mechanisms contribute to communicate mitochondrial fitness to the rest of the cell.
I. Martínez-Reyes, N. Chandel
semanticscholar +1 more source
Transportable hyperpolarized metabolites [PDF]
Nature Communications, 2017 Abstract Nuclear spin hyperpolarization of 13 C-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by ...
Ji, Xiao +8 more
openaire +5 more sources
Plant Secondary Metabolites as Defense Tools against Herbivores for Sustainable Crop Protection
International Journal of Molecular Sciences, 2022 Plants have evolved several adaptive strategies through physiological changes in response to herbivore attacks. Plant secondary metabolites (PSMs) are synthesized to provide defensive functions and regulate defense signaling pathways to safeguard plants ...
Pratap A. Divekar +13 more
semanticscholar +1 more source
Functions of Gut Microbiota Metabolites, Current Status and Future Perspectives
Aging and Disease, 2022 Gut microbiota, a collection of microorganisms that live within gastrointestinal tract, provides crucial signaling metabolites for the physiological of hosts. In healthy state, gut microbiota metabolites are helpful for maintaining the basic functions of
Juan-ru Liu +5 more
semanticscholar +1 more source