Results 41 to 50 of about 1,111,643 (300)

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source

Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes [PDF]

, 2015
This study was supported by funding from the UK Biotechnology and Biological Sciences Research Council Diet and Health Research Industry Club (BBSRC-DRINC) (BB/I006028/1) and by a studentship grant (BB/J500100/1).Scope: Flavonoids are generally studied ...
Kerr, J.S., Zhang, Q., O'Hagan, David, Kerr, Jason, Kay, C.D., Maria A. O'Connell, Sai Krishna Yalamanchili, Raheem, S., David O'Hagan, Colin D. Kay, O'Connell, M.A., O'Hagan, D., di Gesso, J.L., Kay, Colin, Jason S. Kerr, Saki Raheem, Zhang, Qingzhi, Krishna Yalamanchili, Sai, O’Hagan, D., Di Gesso, Jessica, O'Connell, Maria, Raheem, Saki, Yalamanchili, S.K., Jessica L. di Gesso, Qingzhi Zhang   +24 more
core   +1 more source

Transportable hyperpolarized metabolites [PDF]

Nature Communications, 2017
Abstract Nuclear spin hyperpolarization of 13 C-labelled metabolites by dissolution dynamic nuclear polarization can enhance the NMR signals of metabolites by several orders of magnitude, which has enabled in vivo metabolic imaging by ...
Ji, Xiao, Bornet, Aurélien, Vuichoud, Basile, Milani, Jonas, Gajan, David, Rossini, Aaron J., Emsley, Lyndon, Bodenhausen, Geoffrey, Jannin, Sami   +8 more
openaire   +6 more sources

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Detection of volatile metabolites derived from garlic (Allium sativum) in human urine

, 2022
Art. 43, 23 S.The metabolism and excretion of flavor constituents of garlic, a common plant used in flavoring foods and attributed with several health benefits, in humans is not fully understood.
Sharapa, Constanze, Heinlein, Anja, Sauermann, Yvonne, Buettner, Andrea, Scheffler, Laura   +4 more
core   +1 more source

Implication of metabolism in the polarization of tumor-associated-macrophages: the mass spectrometry-based point of view

Frontiers in Immunology, 2023
Tumor-associated macrophages (TAMs) represent one of the main tumor-infiltrating immune cell types and are generally categorized into either of two functionally contrasting subtypes, namely classical activated M1 macrophages and alternatively activated ...
Giulia De Simone, Giulia De Simone, Cristiana Soldani, Aurelia Morabito, Aurelia Morabito, Barbara Franceschini, Fabrizio Ferlan, Guido Costa, Guido Costa, Guido Costa, Roberta Pastorelli, Matteo Donadon, Matteo Donadon, Matteo Donadon, Matteo Donadon, Laura Brunelli   +15 more
doaj   +1 more source

Physiology of metabolites.

, 2012
Abstract This chapter provides an overview of recent research on the effects of genotype fruit development and growing conditions on the synthesis and concentrations of the following metabolites in pepper (Capsicum spp.): antioxidants, carotenoids, phenolic compounds, capsaicinoids, flavonoids and vitamin C.
Frary, Amy, Frary, Anne
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Analysis of Human Faecal Host Proteins: Responsiveness to 10-Week Dietary Intervention Modifying Dietary Protein Intake in Elderly Males

Frontiers in Nutrition, 2021
Faecal proteomics targeting biomarkers of immunity and inflammation have demonstrated clinical application for the identification of changes in gastrointestinal function.
Jessica L. Gathercole, Anita J. Grosvenor, Erin Lee, Ancy Thomas, Cameron J. Mitchell, Cameron J. Mitchell, Nina Zeng, Randall F. D'Souza, Randall F. D'Souza, Farha Ramzan, Pankaja Sharma, Scott O. Knowles, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Nicole C. Roy, Anders Sjödin, Karl-Heinz Wagner, Amber M. Milan, Amber M. Milan, Sarah M. Mitchell, David Cameron-Smith, David Cameron-Smith   +23 more
doaj   +1 more source

Metabolites of Thyroxine.

Experimental Biology and Medicine, 1951
SummaryFollowing injection of I131 labeled L-thyroxine into intact and thyroid-ectomized mice and intact rats, tissues and excreta were investigated by radioautography of paper chromatograms of their butanol extracts. Four substances, namely thyroxine, iodide and two unidentified iodine containing substances referred to as compounds Nos.
J, GROSS, C P, LEBLOND
openaire   +2 more sources