Antioxidant Activity of Three Honey Samples in relation with Their Biochemical Components
The antioxidant activities based on the free radical scavenging, reducing power, and bleaching inhibition were investigated for the three commonly used honeys in Malaysia, namely, tualang, gelam, and acacia honey.
Lee Suan Chua +3 more
doaj +1 more source
Understanding and Classifying Metabolite Space and Metabolite-Likeness
While the entirety of 'Chemical Space' is huge (and assumed to contain between 10(63) and 10(200) 'small molecules'), distinct subsets of this space can nonetheless be defined according to certain structural parameters. An example of such a subspace is the chemical space spanned by endogenous metabolites, defined as 'naturally occurring' products of an
Peironcely, Miguel J.E. +4 more
openaire +6 more sources
Solvent Fractionation and Acetone Precipitation for Crude Saponins from Eurycoma longifolia Extract
Eurycoma longifolia is a popular folk medicine in South East Asia. This study was focused on saccharide-containing compounds including saponins, mainly because of their medical potentials.
Lee Suan Chua +3 more
doaj +1 more source
Chemical defenses of the Caribbean sponges Agelas wiedenmayeri and Agelas conifera [PDF]
Previous studies have determined that Caribbean reef sponges of the genus Agelas are chemically defended from fish predation by brominated pyrrole alkaloids, and that the compounds responsible for this defense have been elucidated for one species, Agelas
Assmann, M. +3 more
core +1 more source
Microbial and metabolic profiling reveal strong influence of water table and land-use patterns on classification of degraded tropical peatlands [PDF]
Tropical peatlands from southeast Asia are undergoing extensive drainage, deforestation and degradation for agriculture and human settlement purposes. This is resulting in biomass loss and subsidence of peat from its oxidation.
S. Mishra +6 more
doaj +1 more source
Luteapyrone, a Novel ƴ-Pyrone Isolated from the Filamentous Fungus Metapochonia lutea
In the process of screening for new bioactive microbial metabolites we found a novel ƴ-pyrone derivative for which we propose the trivial name luteapyrone, in a recently described microscopic filamentous fungus, Metapochonia lutea BiMM-F96/DF4.
Roman Labuda +12 more
doaj +1 more source
Pathos: a web facility that uses metabolic maps to display experimental changes in metabolites identified by mass spectrometry [PDF]
This work describes a freely available web-based facility which can be used to analyse raw or processed mass spectrometric data from metabolomics experiments and display the metabolites identified – and changes in their experimental abundance – in the ...
Barrett, M.P. +3 more
core +2 more sources
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács +8 more
wiley +1 more source
Isolation of 10 cyclosporine metabolites from human bile [PDF]
Ten metabolites of cyclosporine were isolated from the ethyl ether extract of bile from four liver transplant patients receiving cyclosporine. Two of the metabolites were unique and previously unidentified.
Burckart, GJ +7 more
core
New Synthetic Cannabinoids Metabolism and Strategies to Best Identify Optimal Marker Metabolites. [PDF]
Synthetic cannabinoids (SCs) were initially developed as pharmacological tools to probe the endocannabinoid system and as novel pharmacotherapies, but are now highly abused.
Diao, Xingxing, Huestis, Marilyn A.
core +2 more sources

