Journal of Pain and Symptom Management, 2005 The metabolism of opioids closely relates to their chemical structure. Opioids are subject to O-dealkylation, N-dealkylation, ketoreduction, or deacetylation leading to phase-I metabolites. By glucuronidation or sulfatation, phase-II metabolites are formed.
openaire +2 more sources
The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]
, 2014 Phosphopantetheinyltransferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Amy J. Gerc +9 more
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Biology and Life Sciences Forum, 2023 Halophiles are microorganisms that inhabit saline and hypersaline environments, requiring salinity to survive in such extreme conditions. These microorganisms are mainly researched for their biotechnological potential.
Hania Benmebarek, Karima Kharroub
doaj +1 more source
Kawal: A fermented food as a source of Bacillus strain producing antimicrobial peptides
Scientific African, 2023 : Kawal is a fermented food condiment obtained by spontaneous fermentation of Senna obtusifolia leaves. Fermentative microbiota's consists of microorganisms producing a diversity of bioactive molecules.
Blaise Waongo +7 more
doaj +1 more source
Variations in zearalenone activation in avian food species [PDF]
, 2008 Zearalenone (ZEA), a widely distributed oestrogenic fusariotoxin, constitutes a potential risk for human and animal health. ZEA is metabolised to the main metabolites identified in vitro and in vivo: alpha-zearalenol (α-ZOL) and beta-zearalenol (β-ZOL ...
Ayouni, Fatma +3 more
core +1 more source
A screen of Crohn's disease-associated microbial metabolites identifies ascorbate as a novel metabolic inhibitor of activated human T cells. [PDF]
, 2019 Microbial metabolites are an emerging class of mediators influencing CD4+ T-cell function. To advance the understanding of direct causal microbial factors contributing to Crohn's disease, we screened 139 predicted Crohn's disease-associated microbial ...
Borneman, James +19 more
core +1 more source
Intra- and inter-metabolite correlation spectroscopy of tomato metabolomics data obtained by liquid chromatography-mass spectrometry and nuclear magnetic resonance [PDF]
, 2008 Nuclear magnetic resonance (NMR) and liquid chromatography-mass spectrometry (LCMS) are frequently used as technological platforms for metabolomics applications.
Bino, R.J. +4 more
core +2 more sources
Peripheral blood mitochondrial DNA content in relation to circulating metabolites and inflammatory markers: a population study [PDF]
, 2017 Mitochondrial DNA (mtDNA) content might undergo significant changes caused by metabolic derangements, oxidative stress and inflammation that lead to development and progression of cardiovascular diseases.
Brguljan-Hitij, Jana +13 more
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Metabolites of Marine Sediment-Derived Fungi: Actual Trends of Biological Activity Studies
Marine Drugs, 2021 Marine sediments are characterized by intense degradation of sedimenting organic matter in the water column and near surface sediments, combined with characteristically low temperatures and elevated pressures.
Anton N. Yurchenko +2 more
doaj +1 more source
Regulation of cytochrome P450 mRNA expression in primary porcine hepatocytes by selected secondary plant metabolites from chicory (Cichorium intybus L.) [PDF]
, 2013 Chicory (Cichorium intybus) has been shown to induce enzymes of pharmacokinetic relevance (cytochrome P450; CYP). The aim of this study was to investigate the effects of selected secondary plant metabolites with a global extract of chicory root, on the ...
Ekstrand, Bo +2 more
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