Results 261 to 270 of about 2,167,847 (388)

Microbes, metabolites, and the gut–lung axis

Mucosal Immunology, 2019
A. Dang, B. Marsland
semanticscholar   +1 more source

First‐Principles Structure–Activity Relationship Insights Into Phenolic Scaffolds: QSAR Modeling and Drug‐Likeness Screening

Advanced Theory and Simulations, EarlyView.
Integrated machine learning framework for phenolic derivatives: classification (toxicity) and regression (logP) models identify top drug‐like compounds. Random Forest outperformed for toxicity, while Linear Regression best predicted logP. A weighted scoring approach prioritized five safe, lipophilicity‐optimized candidates, supporting rational ...
Houria Nacer, Sridhar Priyankha, Gopal Hema, Anouar Zerouali, Hamza Haddag, Muneerah Mogren Al Mogren, Muthuramalingam Prakash, Majdi Hochlaf   +7 more
wiley   +1 more source

Co-Metabolic Network Reveals the Metabolic Mechanism of Host-Microbiota Interplay in Colorectal Cancer. [PDF]

Metabolites
Wang HW, Li W, Ma QJ, Zhang HY, Quan Y, Zhu Q.   +5 more
europepmc   +1 more source

Cyclosporine and its metabolites in mother and baby [PDF]

, 1988
Burckart, GJ, Caritis, SN, Koneru, B, Paul Wang, CC, Starzl, TE, Venkataramanan, R   +5 more
core   +1 more source

Simultaneous Determination of Enrofloxacin and Its Primary Metabolite Ciprofloxacin in Meat and Fish by HPLC

, 1997
Masakazu Horie, Koichi Saito, Youji Hoshino, Hisaya Terada, Hiroyuki Nakazawa   +4 more
openalex   +2 more sources

Multiomics Analyses Reveal an Essential Role of Tryptophan in Treatment of csDMARDs in Rheumatoid Arthritis

Advanced Science, EarlyView.
Rheumatoid arthritis is a disease characterized by joint inflammation. Approximately 50% of patients show insufficient response to traditional synthetic disease‐modifying antirheumatic drugs. This study aims to elucidate differential molecular profiles of the mechanisms underlying drug responses through multi‐omics strategy.
Congcong Jian, Jing Zhu, Jianhong Wu, Yan Zhang, Jianghua Chen, Huan Wang, Hengyan Liu, Ke Xu, Jiaxin Huang, Xiaoting Zhu, Yuanli Wei, Shilin Li, Tingting Wang, Xuan Huang, Qinghua Zou, Jie Zhang, Jiang Su, Xinming Du, Yaping Lu, Tianci Zhou, Yingtong Zhou, Minglong Tang, Bin Li, Xue Zhou, Qihao Wei, Qiulong Yan, Fanxin Zeng   +26 more
wiley   +1 more source

Effect of Targeted Probiotics on Anesthesia-Induced Sleep Disturbances via Modulating the Gut Microbiome and Metabolites. [PDF]

Food Sci Nutr
Yang RZ, Lin S, Huang LT, Weng J, Liu QM, Chen HS, Ruan N, Zeng K.   +7 more
europepmc   +1 more source

Plasma 1‐carbon metabolites and academic achievement in 15‐yr‐old adolescents

, 2016
Torbjörn Nilsson, Anita Hurtig‐Wennlöf, Michael Sjöstróm, Wolfgang Herrmann, Rima Obeid, Jennifer Owen, Steven H. Zeisel   +6 more
openalex   +2 more sources

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source

Comprehensive Metabolomic-Transcriptomic Analysis of the Regulatory Effects of <i>Armillaria mellea</i> Source Differences on Secondary Metabolism in <i>Gastrodia elata</i>. [PDF]

Biology (Basel)
Han D, Yang C, Bao L, Dong L, He H, Tang P, Zhang Y, Xiong F, Liu H, Yang S.   +9 more
europepmc   +1 more source