The role of the phosphopantetheinyltransferase enzyme, PswP, in the biosynthesis of antimicrobial secondary metabolites by Serratia marcescens Db10 [PDF]
, 2014 Phosphopantetheinyltransferase (PPTase) enzymes fulfil essential roles in primary and secondary metabolism in prokaryotes, archaea and eukaryotes. PPTase enzymes catalyse the essential modification of the carrier protein domain of fatty acid synthases ...
Amy J. Gerc +9 more
core +4 more sources
Gut microbiota-derived metabolites as central regulators in metabolic disorders
Gut, 2020 Metabolic disorders represent a growing worldwide health challenge due to their dramatically increasing prevalence. The gut microbiota is a crucial actor that can interact with the host by the production of a diverse reservoir of metabolites, from ...
A. Agus, K. Clément, H. Sokol
semanticscholar +1 more source
Metabolites of Marine Sediment-Derived Fungi: Actual Trends of Biological Activity Studies
Marine Drugs, 2021 Marine sediments are characterized by intense degradation of sedimenting organic matter in the water column and near surface sediments, combined with characteristically low temperatures and elevated pressures.
Anton N. Yurchenko +2 more
doaj +1 more source
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission. [PDF]
, 2017 Linoleic acid (LA; 18:2 n-6), the most abundant polyunsaturated fatty acid in the US diet, is a precursor to oxidized metabolites that have unknown roles in the brain.
Bazinet, Richard P +11 more
core +1 more source
Antioxidant Activity of Three Honey Samples in relation with Their Biochemical Components
Journal of Analytical Methods in Chemistry, 2013 The antioxidant activities based on the free radical scavenging, reducing power, and bleaching inhibition were investigated for the three commonly used honeys in Malaysia, namely, tualang, gelam, and acacia honey.
Lee Suan Chua +3 more
doaj +1 more source
Solvent Fractionation and Acetone Precipitation for Crude Saponins from Eurycoma longifolia Extract
Molecules, 2019 Eurycoma longifolia is a popular folk medicine in South East Asia. This study was focused on saccharide-containing compounds including saponins, mainly because of their medical potentials.
Lee Suan Chua +3 more
doaj +1 more source
Biochemistry Changes That Occur after Death: Potential Markers for Determining Post-Mortem Interval [PDF]
, 2013 Death is likely to result in very extensive biochemical changes in all body tissues due to lack of circulating oxygen, altered enzymatic reactions, cellular degradation, and cessation of anabolic production of metabolites.
Donaldson, Andrea
core +1 more source
Luteapyrone, a Novel ƴ-Pyrone Isolated from the Filamentous Fungus Metapochonia lutea
Molecules, 2021 In the process of screening for new bioactive microbial metabolites we found a novel ƴ-pyrone derivative for which we propose the trivial name luteapyrone, in a recently described microscopic filamentous fungus, Metapochonia lutea BiMM-F96/DF4.
Roman Labuda +12 more
doaj +1 more source
Human metabolism and elimination of the anthocyanin, cyanidin-3-glucoside: a 13C-tracer study [PDF]
, 2013 BACKGROUND: Evidence suggests that the consumption of anthocyanin-rich foods beneficially affects cardiovascular health; however, the absorption, distribution, metabolism, and elimination (ADME) of anthocyanin-rich foods are relatively unknown. OBJECTIVE:
Aedín Cassidy +50 more
core +1 more source
Understanding and Classifying Metabolite Space and Metabolite-Likeness
PLoS ONE, 2011 While the entirety of 'Chemical Space' is huge (and assumed to contain between 10(63) and 10(200) 'small molecules'), distinct subsets of this space can nonetheless be defined according to certain structural parameters. An example of such a subspace is the chemical space spanned by endogenous metabolites, defined as 'naturally occurring' products of an
Peironcely, Miguel J.E. +4 more
openaire +6 more sources