Results 151 to 160 of about 140,358 (326)

The Amount of Metabolizable Glycine [PDF]

Agricultural and Biological Chemistry, 1972
Michihiro Sugahara, Makoto Kandatsu
openaire   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Cattle herd dynamics: An integer and stochastic model for evaluating production alternatives [PDF]

, 2011
Presents a cattle herd simulation model which is time dynamic, stochastic, non-optimizing & integer and permits the evaluation of herd performance under alternative production regimes; discusses the analytical background to the biological relationships ...
Anderson, F.M., Konandreas, P.A.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Effect of different insoluble dietary fibre sources and level on growth performance and nutrient utilization in broilers

Indian Journal of Animal Sciences
To assess the effect of insoluble dietary fibre sources and level on growth performance and nutrient utilization, a feeding experiment was conducted on day old broiler chicks (n=270) for 35 days under 2×3 factorial arrangement.
M DUBEY, A PANDEY, R DONERIA, M K GENDLEY, S M TRIPATHI , S PRUSTY   +5 more
doaj   +1 more source

Efeito da energia da dieta e do peso ao desmame sobre o balanço de nitrogênio e metabolizabilidade da energia de leitões [PDF]

, 2018
This study aimed to evaluate the effects of dietary metabolizable energy (ME; 3.40, 3.60, or 3.80 Mcal/kg) and weaning weight (WW; 4.5 ± 0.4 and 6.7 ± 0.5 kg) on nitrogen balance (NB) and gross energy metabolizability in weanling piglets.
Batista, Anna Mikaela, Domingues, Victoria Yasmin, Somensi, Marcelo Luiz, Vieira, Marcia de Souza   +3 more
core   +1 more source

サツマイモ加工残さの飼料および食品利用に関する研究 [PDF]

, 2020
鹿児島大学博士(農学)Doctor of Philosophy博士論文全文, 博士論文要旨(English), 博士論文要旨(日本語), 最終試験結果の要旨, 論文審査の要旨doctoral ...
135787, Zhang, Xiaoxiao, 張, 暁霄
core  

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Production performance, carcass characteristics, intestinal morphometry and serum biochemistry in dual purpose chicken fed diet incorporated withrice distillers grain with soluble

Indian Journal of Animal Sciences
This study investigated the effects of rice distillers grains with solubles (rDDGS) on growth performance, production efficiency, carcass characteristics, nutrient metabolizability and serum biochemistry of dual purpose chicken (Kuroiler).
TAPAN KUMAR DAS, DEBALINA KAR, BARUN ROY, BIKAS CHANDRA DEBNATH, JOWEL DEBNATH, BIJOY KUMAR SARKAR, BIPLAB DEBROY, DIBYENDU CHAKRABORTY   +7 more
doaj   +1 more source