Interaction of early metabolizable protein supplementation and virginiamycin on feedlot growth performance and carcass characteristics of calf-fed Holstein steers. [PDF]
Carvalho PHV +4 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Objetivou-se com este trabalho estimar a composição corporal e as exigências nutricionais em proteína e energia para ganho de peso de cabritos ½ Boer ½ SRD, na fase de crescimento, em pastejo na região semiárida. O experimento foi desenvolvido na fazenda‘
Giovanna Henriques da Nóbrega +5 more
doaj
: The influence of diet composition on the degree of adipose and lean muscle mobilization and concentrations of circulating AA has been demonstrated during the transition period.
T.A. Westhoff +4 more
doaj +1 more source
Influence of level of dried distillers grains plus solubles substitution for steam-flaked corn on characteristics of growth performance, and dietary energetics of calf-fed Holstein steers during the initial 16-week growing phase: metabolizable protein versus metabolizable amino acids. [PDF]
Montano MF +4 more
europepmc +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
: The prepartum diet as well as individual metabolic status of the cow influences colostrum parameters. The objectives of this study were to (1) investigate the effect of increasing prepartum dietary MP supply on colostrum yield, composition, and IgG ...
T.A. Westhoff +4 more
doaj +1 more source
Oversupplying metabolizable protein during late gestation to beef cattle does not influence ante- or postpartum glucose-insulin kinetics but does affect prepartum insulin resistance indices and colostrum insulin content. [PDF]
Hare KS, Penner GB, Steele MA, Wood KM.
europepmc +1 more source
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Aerial Inventories of Waterfowl in Illinois and Estimation of Moist-soil Plant Seed Abundance for Waterfowl on Lands Managed by Illinois Department of Natural Resources [PDF]
Grant/Contract No: W-43-R 53-54-55Reports on progress and results of inventories of waterfowl along the Illinois and central Mississippi rivers during fall and winter and estimation of moist-soil plant seed abundance for waterfowl on lands managed by ...
Hine, Christopher S. +4 more
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