Results 121 to 130 of about 151,525 (322)

Unraveling the Evolutionary Diet Mismatch and Its Contribution to the Deterioration of Body Composition

Metabolites
Over the millennia, patterns of food consumption have changed; however, foods were always whole foods. Ultra-processed foods (UPFs) have been a very recent development and have become the primary food source for many people. The purpose of this review is
Sandi Assaf, Jason Park, Naveed Chowdhry, Meghasree Ganapuram, Shelbin Mattathil, Rami Alakeel, Owen J. Kelly   +6 more
doaj   +1 more source

Jia Wei Xiao Yao San ameliorates chronic stress-induced depression-like behaviors in mice by regulating the gut microbiome and brain metabolome in relation to purine metabolism

, 2022
Shuai Ji, Shuangshuang Han, Lin Yu, Lijing Du, Yanting You, Jieyu Chen, Ming Wang, Shengwei Wu, Shasha Li, Xiaomin Sun, Ren Luo, Xiaoshan Zhao   +11 more
openalex   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Intestinal microbiome alterations in pediatric epilepsy: Implications for seizures and therapeutic approaches

Epilepsia Open, EarlyView.
Abstract The intestinal microbiome plays a pivotal role in maintaining host health through its involvement in gastrointestinal, immune, and central nervous system (CNS) functions. Recent evidence underscores the bidirectional communication between the microbiota, the gut, and the brain and the impact of this axis on neurological diseases, including ...
Teresa Ravizza, Greta Volpedo, Antonella Riva, Pasquale Striano, Annamaria Vezzani   +4 more
wiley   +1 more source

Erratum to: Stress-inducible GmGSTU4 shapes transgenic tobacco plants metabolome towards increased salinity tolerance [PDF]

, 2015
Christos Kissoudis, Chrysanthi Kalloniati, Ourania I. Pavli, Emmanouil Flemetakis, Panagiotis Madesis, Nikolaos E. Labrou, Georgios Scaracis, Athanasios Tsaftaris, Irini Nianiou‐Obeidat   +8 more
openalex   +1 more source

Transcriptomic signatures reveal systemic adaptations and immune modulation in response to training and competitive racing in horses

Equine Veterinary Journal, EarlyView.
Abstract Background The molecular mechanisms underlying adaptation to physical exertion and racing stress in horses remain incompletely understood. Peripheral blood transcriptomics offers a minimally invasive method to monitor systemic responses to exercise and identify biomarkers of adaptation or overload. Objectives To evaluate transcriptomic changes
Izabela Dąbrowska, Jowita Grzędzicka‐Agko, Paula Kiełbik, Michał Trela, Olga Witkowska‐Piłaszewicz   +4 more
wiley   +1 more source

Composition Characterization of Crossostephium chinense Leaf Essential Oil and Its Anti-Inflammatory Activity Mechanisms

Plants
This study investigates the composition characteristics and anti-inflammatory activity mechanisms of the essential oil from the leaves of Crossostephium chinense. C.
Chia-Hsin Lin, Yu-Ting Chiang, Li-Yin Lin, Nai-Wen Tsao, Chung-Hsuan Wang, Shih-Chang Chien, Ying-Hsuan Sun, Sheng-Yang Wang   +7 more
doaj   +1 more source

When Rare Is Not Small: Amyotrophic Lateral Sclerosis Initiatives and Therapy

Exploration, EarlyView.
In the precision‐medicine era, rare diseases must not be sidelined in translational infrastructure. The Mr. Cai Lei—led “Ice‐Breaking Team” turns an amyotrophic lateral sclerosis patient community into a sustainable ecosystem, realigning philanthropy, data, and research and development to reshape rare‐disease pipelines and guide precision therapies ...
Yang Liu, Xue Xia, Yingfang Chen, Haoying Yang, Xiaochen Chen, Lei Cai, Bingyang Shi   +6 more
wiley   +1 more source

Functional metabolomics of the human scalp: a metabolic niche for Staphylococcus epidermidis

mSystems
Although metabolomics data acquisition and analysis technologies have become increasingly sophisticated over the past 5–10 years, deciphering a metabolite’s function from a description of its structure and its abundance in a given experimental setting is
Louis-Félix Nothias, Robin Schmid, Allison Garlet, Hunter Cameron, Sabrina Leoty-Okombi, Valérie André-Frei, Regine Fuchs, Pieter C. Dorrestein, Philipp Ternes   +8 more
doaj   +1 more source

Transcriptome and metabolome of syntheticSolanumautotetraploids reveal key genomic stress events following polyploidization [PDF]

, 2016
Carlo Fasano, Gianfranco Diretto, Riccardo Aversano, Nunzio D’Agostino, Antonio Di Matteo, Luigi Frusciante, Giovanni Giuliano, Domenico Carputo   +7 more
openalex   +1 more source