Results 131 to 140 of about 98,733 (348)

Recent Advances in Understanding the Sex Pheromone‐Mediated Communication of Diatoms

ChemPlusChem, EarlyView.
Pheromones control the sexuality and mate finding in diatoms, a group of highly abundant unicellular marine algae. The diatom pheromones presented here are elucidated using a metabolomics‐based approach. This review introduces new structures, methods, and conceptual advances and discusses future perspectives in diatom research.
Franziska Alessandra Klapper, Georg Pohnert   +1 more
wiley   +1 more source

Pyruvate kinase type M2: a crossroad in the tumor metabolome [PDF]

, 2002
S. Mazurek, H. Grimm, C. B. Boschek, Peter Vaupel, E. Eigenbrodt   +4 more
openalex   +1 more source

Repurposing Acebutolol for Osteoporosis Treatment: Insights From Multi‐Omics and Multi‐Modal Data Analysis

Clinical Pharmacology &Therapeutics, EarlyView.
Overview of a multi‐omics based drug repurposing strategy. The systematic drug repurposing strategy included the following steps: (1) osteoporosis driver signaling networks were identified from multi‐omics data; (2) drug functional modules were obtained using a network fusion approach to integrate drug similarity information; (3) all drugs were ranked ...
Dan‐Yang Liu, Hui Shen, Jonathan Greenbaum, Qiao‐Rong Yi, Shuang Liang, Yue Zhang, Jia‐Chen Liu, Chuan Qiu, Lan‐Juan Zhao, Qing Tian, Kuan‐Jui Su, Zhe Luo, Li Wu, Xiang‐He Meng, Hong‐Mei Xiao, Yun Deng, Yang Li, Dragana Lovre, Vivian Fonseca, Fernando L. Sanchez, Li‐Jun Tan, Hong‐Wen Deng   +21 more
wiley   +1 more source

Toward a Cannabis Terroir: Untargeted Metabolomic Profiling of Authentic Samples Using Gas Chromatography–High‐Resolution Mass Spectrometry (GC‐HRMS) and Liquid Chromatography–High‐Resolution Tandem Mass Spectrometry (LC‐HRMS/MS)

Drug Testing and Analysis, EarlyView.
This study developed a comprehensive metabolomics workflow using GC‐HRMS and LC‐HRMS/MS and analyzed 35 CBD‐type cannabis flowers grown under varying conditions. Key discriminative compounds enabled classification by chemical phenotype and cultivation environment. The results showed that environmental factors influence chemical profiles, supporting the
Sandra N. Poetzsch, Michael Poetzsch, Thomas Kraemer, Andrea E. Steuer   +3 more
wiley   +1 more source

Making sense of the metabolome using evolutionary computation: seeing the wood with the trees [PDF]

, 2004
Royston Goodacre
openalex   +1 more source

Antibiotic‐Induced Microbial Dysbiosis Worsened Outcomes in the Activity‐Based Anorexia Model

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a complex psychiatric disorder characterized by persistent dieting and reduced food intake, leading to significantly low body weight. Dysbiosis in the gut microbiome of patients with AN has been suggested to contribute to the pathogenesis.
Karlijn L. Kooij, Nadia Andrea Andreani, Lara Keller, Stefanie Trinh, Luna van der Gun, Jamie Hak, Keith Garner, Mieneke Luijendijk, Lisa Drost, Unna Danner, Annemarie van Elburg, Astrid Dempfle, Jochen Seitz, Beate Herpertz‐Dahlmann, John F. Baines, Roger A. H. Adan   +15 more
wiley   +1 more source

Functional metabolomics of the human scalp: a metabolic niche for Staphylococcus epidermidis

mSystems
Although metabolomics data acquisition and analysis technologies have become increasingly sophisticated over the past 5–10 years, deciphering a metabolite’s function from a description of its structure and its abundance in a given experimental setting is
Louis-Félix Nothias, Robin Schmid, Allison Garlet, Hunter Cameron, Sabrina Leoty-Okombi, Valérie André-Frei, Regine Fuchs, Pieter C. Dorrestein, Philipp Ternes   +8 more
doaj   +1 more source

Tandem mass spectrometry in discovery of disorders of the metabolome [PDF]

, 2004
Arnold W. Strauss
openalex   +1 more source

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

ESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li, Max Homilius, Erin Achilles, Laura K. Massey, Victoria Convey, Åsa Ohlsson, Ingrid Ljungvall, Jens Häggström, Brittany Vester Boler, Pascal Steiner, Sharlene Day, Calum A. MacRae, Mark A. Oyama   +12 more
wiley   +1 more source

Systems Rebalancing of Metabolism in Response to Sulfur Deprivation, as Revealed by Metabolome Analysis of Arabidopsis Plants [PDF]

, 2005
Victoria J. Nikiforova, Joachim Kopka, Vladimir Tolstikov, Oliver Fiehn, Laura Hopkins, Malcolm J. Hawkesford, H. Hesse, Rainer Hoefgen   +7 more
openalex   +1 more source