Results 171 to 180 of about 151,525 (322)

Exploring the impact of microbial dysbiosis on ovarian cancer and the therapeutic potential of probiotics

VIEW, EarlyView.
Ovarian cancer has been linked to the microbiome as a potential environmental contributor, but how this association relates to tumor progression remains unclear. By comparing tumor and nontumor tissues, we identified a severity‐associated microbial and metabolic signature and showed that probiotics can partially restore immune balance and slow tumor ...
Chanyuan Li, Nalan Tu, Xin Ning, Yunyan Cong, Fei Wu, Xiuli Zhang, Runrong Li, Yue Xu, Binqiao Wang, Liqin Jin, Yuanming Shen, Jihong Liu   +11 more
wiley   +1 more source

Sarcosine is uniquely modulated by aging and dietary restriction in rodents and humans [PDF]

, 2018
et al,, Fontana, Luigi, Tosti, Valeria
core   +1 more source

Sphinganine‐phosphate prevents influenza infection via promoting CD8+ T cells proliferation and activation

VIEW, EarlyView.
This study established clinical cohorts of respiratory viral infections and identified sphinganine‐phosphate (SA) as a metabolite significantly upregulated post‐infection through metabolomic analysis. In vitro and in vivo experiments demonstrated that SA promotes the generation of effector CD8+ T cells via the SOCS1/JAK1/STAT1 pathway, which ...
Zhongwen Hu, Guiling Yan, Junhong Li, Yuan Yuan, Hong Zhang, Yuchao Zhong, Yuanyuan Peng, Wenjia Zhang, Xiaoyan Su, Changchun Niu, Yang Luo   +10 more
wiley   +1 more source

Integration of proxy intermediate omics traits into a nonlinear two-step model for accurate phenotypic prediction. [PDF]

Theor Appl Genet
Yoshioka H, Mary-Huard T, Aubert J, Toda Y, Ohmori Y, Yamasaki Y, Tsujimoto H, Takahashi H, Nakazono M, Takanashi H, Fujiwara T, Tsuda M, Kaga A, Inaba J, Fuji Y, Hirai MY, Nose Y, Kumaishi K, Usui E, Kobori S, Sato T, Narukawa M, Ichihashi Y, Iwata H.   +23 more
europepmc   +1 more source

Integrated transcriptome and metabolome analysis reveals the accumulation of secondary metabolites in Camphora glanduliferum ‘Honganzhang’ at different harvest times

Y. B. Yang, Qi Xiang, Yanling Zeng, Y. B. Yang, Jianan Li, Jing Peng   +5 more
openalex   +1 more source

Fungal endophyte exo-metabolites alter the morphology and metabolome of the plant pathogen Fusarium graminearum: an LC-MS based metabolomics approach to unravel the biocontrol effect [PDF]

, 2020
Ameye, Maarten, Audenaert, Kris, De Saeger, Sarah, Fathi Abdallah Abdelmohsen, Mohamed, Gonzales, Gerard, Haesaert, Geert   +5 more
core  

Integrating mass spectrometry and systems biology for the modernization of natural medicines: From deciphering chemical complexity to holistic efficacy assessment

VIEW, EarlyView.
This review explores how mass spectrometry is transforming research in natural medicines, with Traditional Chinese medicine (TCM) as a primary exemplar. It details the application of advanced mass spectrometry in chemical analysis, the development of comprehensive quality control methods, and systematic research on the targeted mechanisms of single ...
Yudian Xu, Linlin Cao, Chenhuan Ding, Chen Wang, Yi Lai, Dan Ru, He Li, Wei Xu   +7 more
wiley   +1 more source

The Effects of Acorn Origin, Environmental Microbiomes and Local Adaptation on the Leaf Metabolome. [PDF]

J Chem Ecol
Ramanathan C, Goris L, Mishra A, Lihavainen-Bag J, Pawlowski K, Albrectsen BR, Tack AJM.   +6 more
europepmc   +1 more source

Cadmium and Selenate Exposure Affects the Honey Bee Microbiome and Metabolome, and Bee-Associated Bacteria Show Potential for Bioaccumulation [PDF]

, 2019
Kirkwood, Jay S, Leger, Laura, McFrederick, Quinn S, Rothman, Jason A   +3 more
core  

Comparison of Three Sympatric Desert Lizards: Digestive Tract Structure, Digestive Enzyme Activities, Gut Microbiota, and Metabolites

Integrative Zoology, EarlyView.
We performed 16S rDNA sequencing and metabolite profiling for three sympatric lizard species—Teratoscincus roborowskii, Phrynocephalus axillaris, and Eremias roborowskii—and compared their goblet cell and enzyme activities in the digestive tract. Our study suggests that the dietary niche may promote divergence or convergence of microbiota across host ...
Yi Yang, Ziyi Wang, Ruichen Wu
wiley   +1 more source