Results 11 to 20 of about 148,249 (221)

Metabolomics [PDF]

open access: yesCell Metabolism, 2007
Metabolomics is the systematic identification and quantitation of all metabolites in a given organism or biological sample. The enhanced resolution provided by nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry (MS), along with powerful chemometric software, allows the simultaneous determination and comparison of thousands of chemical ...
Idle, Jeffrey R., Gonzalez, Frank J.
  +6 more sources

Cardiovascular Metabolomics [PDF]

open access: yesCirculation Research, 2018
Disturbances in cardiac metabolism underlie most cardiovascular diseases. Metabolomics, one of the newer omics technologies, has emerged as a powerful tool for defining changes in both global and cardiac-specific metabolism that occur across a spectrum of cardiovascular disease states.
Robert W, McGarrah   +4 more
openaire   +2 more sources

Aspergillus Metabolome Database for Mass Spectrometry Metabolomics [PDF]

open access: yesJournal of Fungi, 2021
The Aspergillus Metabolome Database is a free online resource to perform metabolite annotation in mass spectrometry studies devoted to the genus Aspergillus. The database was created by retrieving and curating information on 2811 compounds present in 601 different species and subspecies of the genus Aspergillus.
Alberto Gil-de-la-Fuente   +7 more
openaire   +3 more sources

Cell Metabolomics [PDF]

open access: yesOMICS: A Journal of Integrative Biology, 2013
Abstract Metabolomics technologies enable the examination and identification of endogenous biochemical reaction products, revealing information on the precise metabolic pathways and processes within a living cell. Metabolism is either directly or indirectly involved with every aspect of cell function, and metabolomics is thus believed
Aihua, Zhang   +4 more
openaire   +2 more sources

Elemental metabolomics [PDF]

open access: yesBriefings in Bioinformatics, 2017
Elemental metabolomics is quantification and characterization of total concentration of chemical elements in biological samples and monitoring of their changes. Recent advances in inductively coupled plasma mass spectrometry have enabled simultaneous measurement of concentrations of > 70 elements in biological samples.
Zhang, Ping   +2 more
openaire   +3 more sources

Targeted Metabolomics [PDF]

open access: yesCurrent Protocols in Molecular Biology, 2012
AbstractThe metabolome is the terminal downstream product of the genome and consists of the total complement of all the low‐molecular‐weight molecules (metabolites) in a cell, tissue, or organism. Metabolomics aims to measure a wide breadth of small molecules in the context of physiological stimuli or disease states.
Lee D, Roberts   +3 more
openaire   +2 more sources

Experimental Measurements and Mathematical Modeling of Cytosolic Ca2+ Signatures upon Elicitation by Penta-N-acetylchitopentaose Oligosaccharides in Nicotiana tabacum Cell Cultures

open access: yesPlants, 2013
Plants have developed sophisticated recognition systems for different kinds of pathogens. Pathogen-associated molecular patterns (PAMPs) can induce various defense mechanisms, e.g., the production of reactive oxygen species (ROS) as an early event. Plant
Kalina Mrozek   +2 more
doaj   +1 more source

Isorhamnetin Has Potential for the Treatment of Escherichia coli-Induced Sepsis

open access: yesMolecules, 2019
Isorhamnetin is a flavonoid that is abundant in the fruit of Hippophae rhamnoides L. It is widely studied for its ability to modulate inflammatory responses. In this study, we evaluated the potential of isorhamnetin to prevent gram-negative sepsis.
Anil Kumar Chauhan   +4 more
doaj   +1 more source

Methyl lucidone induces apoptosis and G2/M phase arrest via the PI3K/Akt/NF-κB pathway in ovarian cancer cells

open access: yesPharmaceutical Biology, 2020
Context Methyl lucidone (ML) from the dried fruit of Lindera erythrocarpa Makino (Lauraceae) exhibits cytotoxic effects in various cancer cell lines. However, its effects on ovarian cancer cells remain unknown.
Jae-Hwan Yoon   +7 more
doaj   +1 more source

Development of a polyphagous leaf beetle on different host plant species and its detoxification of glucosinolates

open access: yesFrontiers in Ecology and Evolution, 2022
Herbivores face a broad range of defences when feeding on plants. By mixing diets, polyphagous herbivores are assumed to benefit during their development by gaining a better nutritional balance and reducing the intake of toxic compounds from individual ...
Jeanne Friedrichs   +6 more
doaj   +1 more source

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