Results 261 to 270 of about 98,733 (348)

Cloning and Molecular Analysis ofHlbZip1andHlbZip2Transcription Factors Putatively Involved in the Regulation of the Lupulin Metabolome in Hop (Humulus lupulusL.)

, 2009
Jaroslav Matoušek, Tomáš Kocábek, Josef Patzak, Jan Stehlík, Zoltán Füssy, Karel Krofta, Arne Heyerick, Isabel Roldán‐Ruiz, Lina Maloukh, Denis De Keukeleire   +9 more
openalex   +2 more sources

PI5P4K inhibitors: promising opportunities and challenges

The FEBS Journal, EarlyView.
Developing inhibitors is like climbing a steep, challenging mountain. PI5P4K inhibitors hold significant promise for the treatment of cancer, immune disorders, and neurological diseases. However, the path to success is fraught with hurdles, and researchers are therefore required to apply their expertise to overcome critical “checkpoints.” While some ...
Koh Takeuchi, Lisa Nagase, Shun Kageyama, Hirotaka Kanoh, Masashi Oshima, Aki Ogawa‐Iio, Yoshiki Ikeda, Yuki Fujii, Sei Kondo, Natsuki Osaka, Takeshi Masuda, Tsukasa Ishihara, Yoshikazu Nakamura, Yoshihisa Hirota, Takehiko Sasaki, Toshiya Senda, Atsuo T. Sasaki   +16 more
wiley   +1 more source

Correction to "Gut Microbiome and Metabolome Changes in Chronic Low Back Pain Patients With Vertebral Bone Marrow Lesions". [PDF]

JOR Spine
europepmc   +1 more source

Capillary Electrophoresis Electrospray Ionization Mass Spectrometry Reveals Metabolic Perturbations During Nematode Infection in <i>Drosophila melanogaster</i>. [PDF]

Molecules
Tuani YT, Ayon NJ, Onjiko RM, Choi SB, Yadav S, Eleftherianos I, Nemes P.   +6 more
europepmc   +1 more source

Stress exposure in the mdx mouse model of Duchenne muscular dystrophy provokes a widespread metabolic response

The FEBS Journal, EarlyView.
A targeted mass spectrometry‐based metabolomics assay was conducted to identify the impact of stress exposure on the regulation of biological stress pathways in the mdx mouse model of Duchenne muscular dystrophy. We demonstrated a broad shift in the circulating stress‐relevant plasma metabolome associated with stressful scruff handling that was ...
Erynn E. Johnson, James M. Ervasti
wiley   +1 more source

Impact of Low-Level Ergot Alkaloids and Endophyte Presence in Tall Fescue Grass on the Metabolome and Microbiome of Fall-Grazing Steers. [PDF]

Toxins (Basel)
Llada IM, Lourenco JM, Dycus MM, Carpenter JM, Jarrell ZR, Jones DP, Suen G, Hill NS, Filipov NM.   +8 more
europepmc   +1 more source

Discriminating between Different Acute Chemical Toxicities via Changes in the Daphnid Metabolome

, 2010
Nadine S. Taylor, Ralf J. M. Weber, Thomas A. White, Mark R. Viant   +3 more
openalex   +1 more source

Y12C mutation disrupts IMPDH cytoophidia and alters cancer metabolism

The FEBS Journal, EarlyView.
IMPDH, the rate‐limiting enzyme for de novo GTP synthesis, can form polymers and cytoophidia to enhance activity by reducing GTP inhibition. In this study, a Y12C mutation in IMPDH2 was introduced via ABEmax base‐editing in human cancer cell lines to disrupt IMPDH polymerisation.
Chia‐Chun Chang, Min Peng, Gerson Dierley Keppeke, Li‐Kuang Tsai, Ziheng Zhang, Li‐Mei Pai, Li‐Ying Sung, Ji‐Long Liu   +7 more
wiley   +1 more source

Transcriptome and metabolome analyses reveal new insights into the regulatory mechanism of early embryoless seed development in rice. [PDF]

BMC Plant Biol
Liu S, Peng J, Zhang W, Liu J.
europepmc   +1 more source

Sketching T cell atlases in the single‐cell era: challenges and recommendations

Immunology &Cell Biology, EarlyView.
Recent advances in single‐cell technologies have enabled the creation of T cell atlases, providing detailed maps of adaptive immunity across tissues, development and disease states. These atlases help uncover T cell diversity, functional states and disease mechanisms, aiding in the identification of therapeutic targets.
Itana Bojović, António GG Sousa, Sini Junttila, Laura L Elo   +3 more
wiley   +1 more source