Results 111 to 120 of about 210,196 (287)

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy

Advanced Science, EarlyView.
This study successfully engineered vascularized liver organoids (3HLOs) by co‐culturing human reprogrammed hepatocyte‐like cells (hrHLs) with human umbilical vein endothelial cells (HUVECs) and human umbilical mesenchymal stem cells (HUMSCs). Upon implantation, the 3HLOs established functional vascular anastomosis with the host circulation and ...
Kangdi Yang, Xiayan Chu, Xuerui Wang, Wenkun Zhang, Jinnuo Lu, Chuting Xu, Shoucheng Hu, Guoyu Pan, Chih‐Tsung Yang, Xiaohui Zhang, Shaojin Li, Zhaobin Guo, Hanyang Liu, Guangbo Ge   +13 more
wiley   +1 more source

Chemical Exposure Highlighted without Any A Priori Information in an Epidemiological Study by Metabolomic FT-ICR-MS Fingerprinting at High Throughput and High Resolution

, 2023
Baninia Habchi, Sandra Alvès, Sylvie Streel, Michèle Guillaume, Anne‐Françoise Donneau, Brice M. R. Appenzeller, Douglas N. Rutledge, Alain Paris, Estelle Rathahao   +8 more
openalex   +2 more sources

Domestication of Tartary Buckwheat Shaped a Regulatory Module for Seedling Salt Tolerance by Targeting the Magnesium Transporter Gene FtMGT2

Advanced Science, EarlyView.
Domestication of Tartary buckwheat is selected for a salt tolerance mechanism involving the magnesium transporter FtMGT2. Its expression is controlled by the FtAGL16‐FtMYB15L module, which is stabilized under salt stress through a competitive interaction that blocks its degradation by the E3 ligase FtBRG1, ultimately boosting Na⁺ efflux and plant ...
Xiang Lu, Yuqi He, Wenfeng Weng, Zebin Liu, Yuanfen Gao, Yaliang Shi, Wei Li, Dili Lai, Mengyu Zhao, Rintu Jha, Hui Zhao, Guangsheng Li, Chaonan Guan, Shuai Shao, Jingjun Ruan, Sun Hee Woo, Yinan Ouyang, Muriel Quinet, Milen I. Georgiev, Alisdair R. Fernie, Congcong Hou, Kaixuan Zhang, Xu Liu, Meiliang Zhou   +23 more
wiley   +1 more source

Transcriptomics- and Metabolomics-Based Analysis of Key Biological Pathways and Core Genes Involved in the Inhibition Of <i>proteus Mirabilis</i> Biofilm Formation by Protocatechuic Acid

, 2023
Chang Gao, Lu Tian, Jiaxing Lu, Guoli Gong   +3 more
openalex   +1 more source

Conformable Device for Independent Measurements of Mucosal and Vascular Barriers in a Complex In Vitro Intestinal Model

Advanced Science, EarlyView.
Development of more complex in vitro models necessitates the development of improved monitoring approaches. This work demonstrates a novel conformable device capable of measuring the resistance of two cell barriers within a single model independently, a significant advantage over conventional trans‐epithelial/endothelial electrical resistance (TEER ...
Alexandra Elisabeth Wheeler, Sonja Blasche, Rob Bradley, Rachana Acharya, Sophie Oldroyd, David Bulmer, Kiran R. Patil, Róisín Meabh Owens   +7 more
wiley   +1 more source

Using metabolomics to discover the immunomodulator activity of food plants [PDF]

, 2022
Novi Safriani, Fransisca Rungkat Zakaria, Endang Prangdimurti, Suwarti, Robert Verpoorte, Nancy Dewi Yuliana   +5 more
openalex   +1 more source

Multi‐Omics Reveal the Dysregulated Gut‐Joint Axis in Knee Synovitis: Data from Two Osteoarthritis Studies in China

Advanced Science, EarlyView.
The “gut‐joint axis” in knee synovitis is uncovered. Integrated multi‐omics studies are conducted in two independent osteoarthritis cohorts. Synovitis is characterized an increased F/B ratio, as well as alterations of 3‐HIA, geranic acid, and TWEAK. Upregulated TWEAK receptor is found in high‐grade synovitis, and inversely correlated with lower TWEAK ...
Xiaoshuai Wang, Yi Liu, Ziying Sun, Jia Li, Zhihao Lu, Jiayuan Huang, Shixian Hu, Peihua Cao, Xiaolong Cao, Shangru Li, Jianzhao Ruan, Jinhui Liu, Jingyu Xie, Haitao Sun, Tianyu Chen, Shengfa Li, Zhaohua Zhu, Zhibo Wen, Rocky S. Tuan, David John Hunter, Zhong Alan Li, Dongquan Shi, Changhai Ding   +22 more
wiley   +1 more source

Quantifying fecal and plasma short-chain fatty acids in healthy Thai individuals

Computational and Structural Biotechnology Journal
Short-chain fatty acids (SCFAs) are involved in important physiological processes such as gut health and immune response, and changes in SCFA levels can be indicative of disease.
Weerawan Manokasemsan, Narumol Jariyasopit, Patcha Poungsombat, Khwanta Kaewnarin, Kwanjeera Wanichthanarak, Alongkorn Kurilung, Kassaporn Duangkumpha, Suphitcha Limjiasahapong, Yotsawat Pomyen, Roongruedee Chaiteerakij, Rossarin Tansawat, Chatchawan Srisawat, Yongyut Sirivatanauksorn, Vorapan Sirivatanauksorn, Sakda Khoomrung   +14 more
doaj   +1 more source

Metabolomics of Non-Saccharomyces Yeasts in Fermented Beverages [PDF]

, 2022
Daniel Ellis, Edward D. Kerr, Gerhard Schenk, Benjamin L. Schulz   +3 more
openalex   +1 more source

Metabolomics 2015 [PDF]

ELECTROPHORESIS, 2015
openaire   +2 more sources