Results 151 to 160 of about 297,367 (349)

A metabolomics pipeline for the mechanistic interrogation of the gut microbiome

Nature, 2021
Shuo Han, William W. Van Treuren, Curt R. Fischer, Bryan D. Merrill, Brian C. DeFelice, Juan-Maria Sanchez, S. Higginbottom, Leah Guthrie, Lalla A. Fall, Dylan Dodd, M. Fischbach, J. Sonnenburg   +11 more
semanticscholar   +1 more source

Metabolomic profiling of stool of two‐year old children from the INSIGHT study reveals links between butyrate and child weight outcomes [PDF]

, 2021
Debmalya Nandy, Sarah J. C. Craig, Jingwei Cai, Yuan Tian, Ian M. Paul, Jennifer S. Savage, Michele E. Marini, Emily E. Hohman, Matthew Reimherr, Andrew D. Patterson, Kateryna D. Makova, Francesca Chiaromonte   +11 more
openalex   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

Advanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong, Weinan Guo, Yuxuan Qian, Wenyan Jin, Xiaozhen Li, Jingyuan Yang, Qingrong Ni, Shuang Wu, Fanni Li, Hua Wang, Chunying Li, Hong Cai   +11 more
wiley   +1 more source

Radical Oxygen Species, Oxidized Low-Density Lipoproteins, and Lectin-like Oxidized Low-Density Lipoprotein Receptor 1: A Vicious Circle in Atherosclerotic Process

Antioxidants
Atherosclerosis is a complex condition that involves the accumulation of lipids and subsequent plaque formation in the arterial intima. There are various stimuli, cellular receptors, and pathways involved in this process, but oxidative modifications of ...
Marco Munno, Alice Mallia, Arianna Greco, Gloria Modafferi, Cristina Banfi, Sonia Eligini   +5 more
doaj   +1 more source

Lung microbiota in the acute respiratory disease: from coronavirus to metabolomics

, 2020
Vassilios Fanos, Maria Cristina Pintus, Roberta Pintus, Maria Antonietta Marcialis   +3 more
openalex   +2 more sources

Targeting unique biological signals on the fly to improve MS/MS coverage and identification efficiency in metabolomics

, 2021
Kevin Cho, Michaela Schwaiger-Haber, Fuad J. Naser, Ethan Stancliffe, Miriam Sindelar, Gary J. Patti   +5 more
openalex   +1 more source

Long‐Term Elevated CO2 Improves Soil Health and Rice Yields in Paddy Fields

Advanced Science, EarlyView.
Combining the two longest‐running rice free‐air CO2 enrichment experiments with a global data synthesis, this study demonstrates that long‐term elevated CO2 consistently enhances soil health. In rice paddies, this improvement sustains the CO2 fertilization effect over decades.
Fan Jiang, Wenchao Du, Kees Jan van Groenigen, Josep Peñuelas, Scott X. Chang, Lian Song, Chuang Cai, Yu Wang, Lin Deng, Zhengkun Hu, Weishou Shen, Qicong Wu, Haiyang Yu, Ying Yin, Fuxun Ai, Wei Zhou, Dongming Wang, Jianqiang Sun, Xiaoyuan Yan, Renfang Shen, Jiabao Zhang, Hongyan Guo, Chunwu Zhu   +22 more
wiley   +1 more source

CircadiOmics: integrating circadian genomics, transcriptomics, proteomics and metabolomics

Nature Methods, 2012
D. Darriba, G. L. Taboada, R. Doallo, D. Posada   +3 more
semanticscholar   +1 more source

Providing metabolomics education and training: pedagogy and considerations [PDF]

, 2022
Catherine Winder, Michael Witting, Fidele Tugizimana, Warwick B. Dunn, Stacey N. Reinke   +4 more
openalex   +1 more source

Microglial Deletion of Hrh4 Alleviates Alzheimer's Disease Pathologies by Enhancing Microglial Phagocytosis of Amyloid‐β and Tau

Advanced Science, EarlyView.
Histamine H4 receptor (H4R) antagonist VUF6002 mimics low‐dose X‐ray irradiation in aged Alzheimer's disease (AD) mice, enhancing microglial clearance of amyloid‐beta/hyperphosphorylated tau aggregates and restoring cognition. Microglial H4R deletion activates cAMP/TGF‐β1/Smad3 pathway, enhancing phagocytosis, while TGF‐β receptor 1 deletion abolishes ...
Yi‐Jun Xu, Tan Wu, Larry Tso‐Lun Lo, Chi‐Chiu Ko, Xin Wang, Chi Him Eddie Ma   +5 more
wiley   +1 more source