Results 191 to 200 of about 393,797 (377)
Metabolomics in rheumatology [PDF]
Rheumatology, 2015 Kapoor, Sabrina R +3 more
openaire +4 more sources
Loss of STARD7 Triggers Metabolic Reprogramming and Cell Cycle Arrest in Breast Cancer
Advanced Science, EarlyView.Breast cancer cells undergo metabolic and transcriptomic reprogramming to support aberrant cell proliferation. Their mitochondria rely on the transfer of phosphatidylcholine from the endoplasmic reticulum to their membranes by STARD7, a candidate upregulated in breast cancer, to be functional.
Ewelina Dondajewska +18 more
wiley +1 more source
Plant metabolomics: from holistic hope, to hype, to hot topic [PDF]
, 2006 Robert D. Hall
openalex +1 more source
Advanced Science, EarlyView.This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai +9 more
wiley +1 more source
The critical role that spectral libraries play in capturing the metabolomics community knowledge
Metabolomics, 2022 Wout Bittremieux +2 more
semanticscholar +1 more source
Centering, scaling, and transformations: improving the biological information content of metabolomics data [PDF]
, 2006 Robert A. van den Berg +4 more
openalex +1 more source
Advanced Science, EarlyView.Biosynthesis rates of 13 FFAs are quantitatively calculated in 15 tissues from glucose and an analytical framework to quantitatively calculate inter‐tissue communications of fatty acids between the liver and other tissues is developed. Moreover, the approach is extended to aging condition and a system‐wide decline of fatty acid synthesis in peripheral ...
Beizi Xing +4 more
wiley +1 more source
Systems biology, metabolic modelling and metabolomics in drug discovery and development [PDF]
, 2006 Douglas B. Kell
openalex +1 more source
Advanced Science, EarlyView.γGC deficiency in ulcerative colitis drives macrophage ferroptosis‐mediated inflammation. Claw‐engaged microparticles armed with γGC (γGC‐MPs) enhance lesion targeting, promoting localized γGC release and tissue uptake. On the cover, Monkey King (Macrophages) was bound by the Immortal‐Binding Rope and subsequently sealed beneath the Five‐Fingered ...
Rong Wang +10 more
wiley +1 more source