Metabolomics Standards Workshop and the development of international standards for reporting metabolomics experimental results [PDF]
, 2006 Arthur L. Castle
openalex +1 more source
Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset
Advanced Science, EarlyView.This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu +9 more
wiley +1 more source
PNU-91325 increases fatty acid synthesis from glucose and mitochondrial long chain fatty acid degradation: a comparative tracer-based metabolomics study with rosiglitazone and pioglitazone in HepG2 cells [PDF]
, 2006 George G. Harrigan +3 more
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The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
Metabolomics: beyond biomarkers and towards mechanisms
Nature reviews. Molecular cell biology, 2016 C. Johnson, J. Ivanisevic, G. Siuzdak
semanticscholar +1 more source
Proceedings from the 4th International Plant Metabolomics Conference [PDF]
, 2006 Jane L. Ward, Michael H. Beale
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Genetic Impacts on the Structure and Mechanics of Cellulose Made by Bacteria
Advanced Science, EarlyView.A genetic mutation in a protease of a cellulose‐overproducing evolved bacterium significantly affects the proteome, structure, and mechanical properties of bio‐fabricated cellulose pellicles. By overexpressing synthase proteins that build the cellulose‐forming biological machinery of the cell, the evolved bacterium generates dense, stiff, and strong ...
Julie M. Laurent +8 more
wiley +1 more source
A metabolomic study of substantial equivalence of field‐grown genetically modified wheat [PDF]
, 2006 John M. Baker +6 more
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Advanced Science, EarlyView.This study identifies the RUNX1/SLAMF3 axis as a key driver of colorectal cancer liver metastasis (CRLM). SLAMF3 suppresses macrophage phagocytosis and depletes C1QC⁺ tumor‐associated macrophages, promoting an immunosuppressive microenvironment. Targeting this axis restores macrophage and CD8⁺ T cell activity and reduces metastasis.
Yinheng Luo +10 more
wiley +1 more source
In-Depth Glycoproteomic Assay of Urinary Prostatic Acid Phosphatase
ACS Measurement Science Au, 2023 Wei Wang +3 more
doaj +1 more source