Results 221 to 230 of about 393,797 (377)

Metabolic alterations in human pulmonary artery smooth muscle cells treated with PDGF‐BB

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Metabolic abnormalities are considered to play a key regulatory role in vascular remodeling of pulmonary arterial hypertension. We analyzed the metabolome in the culture supernatants of human pulmonary artery smooth muscle cells (PASMC) during the malignant proliferation phenotype transition via a targeted metabolomics method. Significant and extensive
Meng‐Jie Zhang   +9 more
wiley   +1 more source

NMR-based metabolomics at work in phytochemistry [PDF]

open access: hybrid, 2007
Robert Verpoorte   +2 more
openalex   +1 more source

Decoding the Chemical Language of Ribosomally Synthesized and Post‐Translationally Modified Peptides from the Untapped Archaea Domain

open access: yesAngewandte Chemie, EarlyView.
Secondary metabolites (SMs) are essential across all life domains, yet those originating from the Archaea domain remain poorly understood. Here, the systematic genome mining and the pioneering heterologous expression of archaeal SMs have revealed the chemical landscape of archaeal lanthipeptides, showing both canonical and non‐canonical forms.
Zhi‐Man Song   +13 more
wiley   +2 more sources

Identifying the optimal dose of cannabidiol by intrabuccal administration in Kramnik (C3HeB/FeJ) mice

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Cannabidiol (CBD) has numerous therapeutic properties, and is used to treat neurological conditions, such as neuroinflammation. However, the optimal dose of CBD to penetrate the brain requires further investigation. The primary aim of this study was to use a mouse model and the intrabuccal route for CBD administration to determine the optimal dose at ...
Oluwadara Pelumi Omotayo   +4 more
wiley   +1 more source

Toward Supportive Data Collection Tools for Plant Metabolomics

open access: green, 2005
Helen Jenkins   +4 more
openalex   +1 more source

Bifidobacterium animalis subsp. lactis modulates early‐life immune response and gut metabolism

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Background: The maturation of the immune system is critical during early life, as it involves the differentiation, maturation, and establishment of immune tolerance of immune cells. This process is influenced not only by genetic factors but also by environmental factors, particularly the symbiotic microbiota. Bifidobacterium animalis subsp.
Haoming Du   +17 more
wiley   +1 more source

Publisher Correction: Suspect screening analysis to improve untargeted and targeted UHPLC-qToF approaches: the biodegradability of a proton pump inhibitor medicine and a natural medical device

open access: yesScientific Reports
Luisa Mattoli   +8 more
doaj   +1 more source

Atherosclerosis and liver inflammation induced by increased dietary cholesterol intake: a combined transcriptomics and metabolomics analysis [PDF]

open access: hybrid, 2007
Robert Kleemann   +16 more
openalex   +1 more source

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