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Advancing Untargeted Metabolomics Through FT-ICR-MS: Challenges and Applications. [PDF]
Silva MS, Cordeiro C.
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Reverse metabolomics for the discovery of chemical structures from humans
Nature, 2023Determining the structure and phenotypic context of molecules detected in untargeted metabolomics experiments remains challenging. Here we present reverse metabolomics as a discovery strategy, whereby tandem mass spectrometry spectra acquired from newly ...
Emily C. Gentry +29 more
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Trends in Endocrinology & Metabolism, 2021
Skin retains numerous low-molecular-weight compounds (metabolites). Some of these compounds fulfill specific physiological roles, while others are by-products of metabolism. The skin surface can be sampled to detect and quantify skin metabolites related to diseases.
Decibel P. Elpa +3 more
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Skin retains numerous low-molecular-weight compounds (metabolites). Some of these compounds fulfill specific physiological roles, while others are by-products of metabolism. The skin surface can be sampled to detect and quantify skin metabolites related to diseases.
Decibel P. Elpa +3 more
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Current Drug Metabolism, 2008
Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic
V S, Gomase +3 more
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Metabolomics is based on the simultaneous analysis of multiple low-molecular-weight metabolites from a given sample. The goals of metabolomics are to catalog and quantify the myriad small molecules found in biological fluids under different conditions. The metabolomics represents the collection of all metabolites in a biological organism, and metabolic
V S, Gomase +3 more
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Using MetaboAnalyst 4.0 for Comprehensive and Integrative Metabolomics Data Analysis
Current Protocols in Bioinformatics, 2019MetaboAnalyst (https://www.metaboanalyst.ca) is an easy‐to‐use web‐based tool suite for comprehensive metabolomic data analysis, interpretation, and integration with other omics data.
Jasmine Chong, D. Wishart, J. Xia
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Archivos de Bronconeumología, 2023
The clinical presentation of chronic obstructive pulmonary disease (COPD) is highly heterogeneous. Attempts have been made to define subpopulations of patients who share clinical characteristics (phenotypes and treatable traits) and/or biological characteristics (endotypes), in order to offer more personalized care.
Joaquim, Gea +2 more
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The clinical presentation of chronic obstructive pulmonary disease (COPD) is highly heterogeneous. Attempts have been made to define subpopulations of patients who share clinical characteristics (phenotypes and treatable traits) and/or biological characteristics (endotypes), in order to offer more personalized care.
Joaquim, Gea +2 more
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Metabolomics as a tool for the early diagnosis and prognosis of diabetic kidney disease
Medicinal research reviews (Print), 2022Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes mellitus and the leading cause of the end‐stage renal disease (ESRD).
Pedro R Pereira +5 more
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Recent advances in LC-MS-based metabolomics for clinical biomarker discovery.
Mass spectrometry reviews (Print), 2022The employment of liquid chromatography-mass spectrometry (LC-MS) untargeted and targeted metabolomics has led to the discovery of novel biomarkers and improved the understanding of various disease mechanisms.
Chao-Jung Chen +4 more
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