Results 41 to 50 of about 297,367 (349)
The metabolomics of human aging: Advances, challenges, and opportunities
Science Advances, 2022 As the global population becomes older, understanding the impact of aging on health and disease becomes paramount. Recent advancements in multiomic technology have allowed for the high-throughput molecular characterization of aging at the population ...
D. Panyard, B. Yu, M. Snyder
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Metabolites, 2021 Lipid metabolism is tightly linked to adiposity. Comprehensive lipidomic profiling offers new insights into the dysregulation of lipid metabolism in relation to weight gain.
Habtamu B. Beyene +9 more
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Applications of machine learning in metabolomics: Disease modeling and classification
Frontiers in Genetics, 2022 Metabolomics research has recently gained popularity because it enables the study of biological traits at the biochemical level and, as a result, can directly reveal what occurs in a cell or a tissue based on health or disease status, complementing other
A. Galal, Marwa Talal, Ahmed Moustafa
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Scientific Reports, 2017 Sialylation is a glycosylation feature that occurs in different linkages at the non-reducing end of a glycan moiety, the linkage isomers are often differentially associated with various biological processes.
Guinevere S. M. Kammeijer +7 more
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Nucleic Acids ResearchWe introduce MetaboAnalyst version 6.0 as a unified platform for processing, analyzing, and interpreting data from targeted as well as untargeted metabolomics studies using liquid chromatography - mass spectrometry (LC–MS).
Zhiqiang Pang +10 more
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Cold Spring Harbor Protocols, 2017 Budding yeast has from the beginning been a major eukaryotic model for the study of metabolic network structure and function. This is attributable to both its genetic and biochemical capacities and its role as a workhorse in food production and biotechnology.
Amy A, Caudy +2 more
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Metabolomics, 2022 Untargeted metabolomics approaches based on mass spectrometry obtain comprehensive profiles of complex biological samples. However, on average only 10% of the molecules can be annotated.
Niek F. de Jonge +6 more
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MetaboAnalystR 4.0: a unified LC-MS workflow for global metabolomics
Nature CommunicationsThe wide applications of liquid chromatography - mass spectrometry (LC-MS) in untargeted metabolomics demand an easy-to-use, comprehensive computational workflow to support efficient and reproducible data analysis.
Zhiqiang Pang +6 more
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Cancer Reports, 2023 AbstractBackgroundOncogenic transformation alters intracellular metabolism and contributes to the growth of malignant cells. Metabolomics, or the study of small molecules, can reveal insight about cancer progression that other biomarker studies cannot.
Gurparsad Singh Suri +3 more
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Metabolomics in Diabetes and Diabetic Complications: Insights from Epidemiological Studies
Cells, 2021 The increasing prevalence of diabetes and its complications, such as cardiovascular and kidney disease, remains a huge burden globally. Identification of biomarkers for the screening, diagnosis, and prognosis of diabetes and its complications and better ...
Qiao Jin, R. Ma
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