Results 101 to 110 of about 7,923 (211)
Frontiers in PharmacologyThe ancient Chinese medicinal formula, Dayuan Yin (DYY), has a long history of use in treating respiratory ailments and is shown to be effective in treating acute infectious diseases.
Lei Zhang, Wei Zhu, Zepeng Zhang
doaj +1 more source
, 2004 Metabonomics, the study of metabolites and their roles in various disease states, is a novel methodology arising from the post-genomics era. This methodology has been applied in many fields.
Kong, HW +6 more
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Where and how to 'fish' disease-related metabolite biomarkers by using LC-MS based metabonomics
, 2010 Complex diseases such as cancer, diabetes and obesity arise from an intricate interaction of inherited–nature and environmental–nurture factors. Their (early) diagnosis is very difficult, especially based on only singular biomarker.
陈世礼 +9 more
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Frontiers in PharmacologyBackgroundDiabetes is one common clinical symptoms of metabolic disorders. The peel of Zea mays L. is a folk remedy for diabetes that has not been thoroughly studied.
Xiaotian Cheng +8 more
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, 2011 A method for handling metabonomics data from liquid chromatography/mass spectrometry: combinational use of support vector machine recursive feature elimination, genetic algorithm and random forest for feature ...
WangQuancai +7 more
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Metabonomics and Gut Microbial Paradigm in Healthy Aging
, 2014 Metabonomics, aiming to characterize the pattern of low molecular weight metabolites participating in metabolic pathways, is a valuable tool to detect changes in metabolic regulation and subsequently link them to the health outcome, emerging as a ...
Patrizia Brigidi +11 more
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, 2006 Metabonomics methods have been successfully applied to the drug discovery, toxicology, phytochemistry, and clinical fields. Here, we report a self-developed metabonomics platform which is based on high performance liquid chromatog raphy- mass ...
许国旺 +10 more
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Investigation of the curative effect of losartan on the diabetes mellitus by GC-based metabonomics
, 2007 The aim of the study was to assess the feasibility of metabonomics in clinical studies and the curative effect of drug. It is projected that type 2 diabetes will be the biggest killer in the western world by 2020.
袁凯龙 +4 more
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Study of NMR Analysis Technology of Body Fluid in Metabonomics [PDF]
, 2008 中文摘要 自从1999年Nicholson及其同事在核磁共振(NMR)研究的基础上提出代谢组学(Metabonomics)概念以来，基于NMR代谢组学得到了迅速地发展。基于NMR的代谢组学的直接研究对象是样品的NMR谱，因此基于NMR的代谢组学与NMR分析技术息息相关。有效的水峰抑制、良好的谱图相位和平整的基线对代谢组学的后续统计处理至关重要。 本文对代谢组学中使用的NMR分析技术进行了总结概括，并且以糖尿病患者和正常人的体液样品为对象，进行了不同序列、不同核匀场的NMR实验 ...
肖娴
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Separation Science in the Context of Metabonomics: Current Platforms and Future Trends
, 2009 As an indispensable technique in the context of systems biology, metabonomics/metabolomics has been proposed for over ten years and has become the focus of life sciences in the fields of drug development, healthy and plant research.
Xu Guowang +4 more
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