Results 141 to 150 of about 54,675 (202)

Metabotropic glutamate receptor 5 (mGluR5) is associated with neurodegeneration and amyloid deposition in Alzheimer's disease: A [¹⁸F]PSS232 PET/MRI study. [PDF]

Alzheimers Res Ther
Wang J, He Y, Chen X, Huang L, Li J, You Z, Huang Q, Ren S, He K, Schibli R, Mu L, Guan Y, Guo Q, Zhao J, Xie F.   +14 more
europepmc   +1 more source

Presynaptic density determined by SV2A PET is closely associated with postsynaptic metabotropic glutamate receptor 5 availability and independent of amyloid pathology in early cognitive impairment. [PDF]

Alzheimers Dement
Wang J, Huang Q, He K, Li J, Guo T, Yang Y, Lin Z, Li S, Vanderlinden G, Huang Y, Van Laere K, Guan Y, Guo Q, Ni R, Li B, Xie F.   +15 more
europepmc   +1 more source

The protective effects of methylene blue on astrocytic swelling after cerebral ischemia-reperfusion injuries are mediated by Aquaporin-4 and metabotropic glutamate receptor 5 activation. [PDF]

Heliyon
Lai Y, Han J, Qiu D, Liu X, Sun K, Fan Y, Wang C, Zhang S.   +7 more
europepmc   +1 more source

Plasma endocannabinoids in cocaine dependence and their interaction with cocaine craving and metabotropic glutamate receptor 5 density in the human brain

, 2023
Kroll SL, Hulka LM, Kexel A, Vonmoos M, Preller KH, Treyer V, Ametamey SM, Baumgartner MR, Boost C, Pahlisch F, Rohleder C, Leweke FM, Quednow BB.   +12 more
europepmc   +1 more source

Metabotropic Glutamate Receptor 4 (mGlu4) Positive Allosteric Modulators Lack Efficacy in Rat and Marmoset Models of L-DOPA-Induced Dyskinesia. [PDF]

J Parkinsons Dis
Finlay CJ, Jackson MJ, Fisher R, Bundgaard C, Rose S, Duty S.   +5 more
europepmc   +1 more source

Modulation of Type 5 Metabotropic Glutamate Receptor-Mediated Intracellular Calcium Mobilization by Regulator of G Protein Signaling 4 (RGS4) in Cultured Astrocytes. [PDF]

Cells
Beckers P, Doyen PJ, Hermans E.
europepmc   +1 more source

Erratum: Shannonhouse et al., "Meclizine and Metabotropic Glutamate Receptor Agonists Attenuate Severe Pain and Ca²⁺ Activity of Primary Sensory Neurons in Chemotherapy-Induced Peripheral Neuropathy". [PDF]

J Neurosci
europepmc   +1 more source

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Metabotropic glutamate receptors

Cell and Tissue Research, 2006
Metabotropic glutamate receptors (mGlus) are a family of G-protein-coupled receptors activated by the neurotransmitter glutamate. Molecular cloning has revealed eight different subtypes (mGlu1-8) with distinct molecular and pharmacological properties. Multiplicity in this receptor family is further generated through alternative splicing. mGlus activate
Ferraguti F., Shigemoto R.
openaire   +3 more sources

Metabotropic glutamate receptors

Amino Acids, 2007
l-Glutamate, one of the main neurotransmitters in the central nervous system (CNS), acts on two groups of receptors: (a) a group of ionotropic receptors that includes N-methyl-d-aspartate (NMDA), α-amino-3-hydroxy-5-methylisoxazole-4-propionate (AMPA), and kainate receptors, and (2) a group of metabotropic receptors (mGluRs).
Andrzej Pilc, Krystyna Ossowska
openaire   +2 more sources

Structure of the metabotropic glutamate receptor

Current Opinion in Neurobiology, 2003
In the twelve years since the molecular elucidation of the metabotropic glutamate receptor subtype 1, a class III family of G-protein-coupled receptors has emerged; members of this family include the calcium-sensing receptor, the GABA(B) receptor, some odorant receptors and some taste receptors.
Shigetada Nakanishi, Hisato Jingami, Kosuke Morikawa   +2 more
openaire   +2 more sources