Results 191 to 200 of about 116,544 (286)

Effectiveness of positive allosteric modulators of metabotropic glutamate receptor 2/3 (mGluR2/3) in animal models of schizophrenia. [PDF]

Transl Psychiatry
Olivares-Berjaga D, Martínez-Pinteño A, Rodríguez N, Mas S, Morén C, Parellada E, Gassó P.   +6 more
europepmc   +1 more source

Distinct roles of metabotropic glutamate receptor dimerization in agonist activation and G-protein coupling

Proceedings of the National Academy of Sciences of the United States of America, 2012
Driss El Moustaine, S. Granier, E. Doumazane, P. Scholler, Rita Rahmeh, P. Bron, B. Mouillac, J. Banères, P. Rondard, J. Pin   +9 more
semanticscholar   +1 more source

Discovery of Thieno[3,2-<i>b</i>]pyridine-5-carboxamide and 2,3-Difluorobenzamide Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5. [PDF]

ACS Med Chem Lett
Crocker KE, Henderson SH, Capstick RA, Whomble DL, Bender AM, Felts AS, Han C, Engers JL, Billard NB, Maurer MA, Cho HP, Rodriguez AL, Niswender CM, O'Neill J, Watson KJ, Chang S, Blobaum AL, Boutaud O, Peng W, Rook JM, Conn PJ, Lindsley CW, Temple KJ.   +22 more
europepmc   +1 more source

Structural basis of positive allosteric modulation of metabotropic glutamate receptor activation and internalization. [PDF]

Nat Commun
Strauss A, Gonzalez-Hernandez AJ, Lee J, Abreu N, Selvakumar P, Salas-Estrada L, Kristt M, Arefin A, Huynh K, Marx DC, Gilliland K, Melancon BJ, Filizola M, Meyerson J, Levitz J.   +14 more
europepmc   +1 more source

Molecular characterization of a novel metabotropic glutamate receptor mGluR5 coupled to inositol phosphate/Ca2+ signal transduction.

Journal of Biological Chemistry, 1992
Takaaki Abe, H. Sugihara, H. Nawa, R. Shigemoto, N. Mizuno, S. Nakanishi   +5 more
semanticscholar   +1 more source

Activation of Endoplasmic Reticulum-Localized Metabotropic Glutamate Receptor 5 (mGlu₅) Triggers Calcium Release Distinct from Cell Surface Counterparts in Striatal Neurons. [PDF]

Biomolecules
Jong YI, Harmon SK, O'Malley KL.
europepmc   +1 more source

Therapeutic Potential for Metabotropic Glutamate Receptor 7 Modulators in Cognitive Disorders. [PDF]

Mol Pharmacol
Parent HH, Niswender CM.
europepmc   +1 more source

Metabotropic Glutamate Receptor Technologies

Metabotropic Glutamate Receptor Technologies
Positron Emission Tomography (PET) Imaging of Metabotropic Glutamate Receptor Subtype 2 (mGlu2) Based on a Negative Allosteric Modulator ...
openaire  

Genome-wide copy number variation study associates metabotropic glutamate receptor gene networks with attention deficit hyperactivity disorder

Nature Genetics, 2011
Josephine Elia, Josephine Elia, J. Glessner, Kai Wang, N. Takahashi, Corina J Shtir, D. Hadley, P. Sleiman, Haitao Zhang, Cecilia Kim, Reid J. Robison, G. Lyon, J. Flory, J. Bradfield, M. Imieliński, C. Hou, E. Frackelton, R. Chiavacci, T. Sakurai, C. Rabin, F. Middleton, Kelly Thomas, M. Garris, F. Mentch, C. Freitag, Hans-Christoph Steinhausen, Hans-Christoph Steinhausen, Hans-Christoph Steinhausen, A. Todorov, A. Reif, A. Rothenberger, B. Franke, E. Mick, H. Roeyers, J. Buitelaar, K. Lesch, T. Banaschewski, R. Ebstein, F. Mulas, R. Oades, J. Sergeant, E. Sonuga-Barke, E. Sonuga-Barke, E. Sonuga-Barke, T. Renner, M. Romanos, J. Romanos, A. Warnke, Susanne Walitza, Susanne Walitza, Jobst Meyer, H. Pálmason, C. Seitz, S. Loo, S. Smalley, J. Biederman, L. Kent, P. Asherson, R. Anney, J. Gaynor, P. Shaw, M. Devoto, P. White, S. F. Grant, S. F. Grant, J. Buxbaum, J. Rapoport, N. Williams, S. Nelson, S. Faraone, H. Hakonarson   +70 more
semanticscholar   +1 more source

Radiosynthesis and preclinical evaluation of a carbon-11 labeled PET ligand for imaging metabotropic glutamate receptor 7. [PDF]

Am J Nucl Med Mol Imaging
Li Y, Xiao Z, Mori W, Sun J, Yamasaki T, Rong J, Fujinaga M, Chen J, Kumata K, Zhao C, Zhang Y, Collier TL, Hu K, Xie L, Zhou X, Zhang W, Song Z, Gao Y, Sun Z, Zhang K, Patel JS, Ran C, Chaudhary A, Sheffler DJ, Cosford ND, Zhang L, Zhai C, Haider A, Yuan H, Zhang MR, Liang SH.   +30 more
europepmc   +1 more source