Results 111 to 120 of about 52,982 (243)

Neuroprotection and Functional Recovery Associated with Decreased Microglial Activation Following Selective Activation of mGluR2/3 Receptors in a Rodent Model of Parkinson's Disease

Parkinson's Disease, 2010
Clinical trials have demonstrated positive proof of efficacy of dual metabotropic glutamate receptor 2/3 (mGluR2/3) agonists in both anxiety and schizophrenia.
Hugh Chan, Helen Paur, Anthony C. Vernon, Virginia Zabarsky, Krishna P. Datla, Martin J. Croucher, David T. Dexter   +6 more
doaj   +1 more source

Experience-dependent plasticity without long-term depression by type 2 metabotropic glutamate receptors in developing visual cortex [PDF]

, 2002
John J. Renger, Kenichi N. Hartman, Yoshiko Tsuchimoto, Mineto Yokoi, Shigetada Nakanishi, Takao K. Hensch   +5 more
openalex   +1 more source

Two Intracellular Pathways Mediate Metabotropic Glutamate Receptor-Induced Ca²⁺Mobilization in Dopamine Neurons [PDF]

, 2003
Hitoshi Morikawa, Kamran Khodakhah, John T. Williams   +2 more
openalex   +1 more source

Synthesis and Characterization of 5-(2-Fluoro-4-[¹¹C]methoxyphenyl)-2,2-dimethyl-3,4-dihydro-2H-pyrano[2,3-b]pyridine-7-carboxamide as a PET Imaging Ligand for Metabotropic Glutamate Receptor 2. [PDF]

J Med Chem, 2022
Yuan G, Dhaynaut M, Lan Y, Guehl NJ, Huynh D, Iyengar SM, Afshar S, Jain MK, Pickett JE, Kang HJ, Wang H, Moon SH, Ondrechen MJ, Wang C, Shoup TM, El Fakhri G, Normandin MD, Brownell AL.   +17 more
europepmc   +1 more source

Metabotropic Glutamate Receptor Activation Enhances the Activities of Two Types of Ca²⁺-Activated K⁺Channels in Rat Hippocampal Astrocytes [PDF]

, 2003
Debebe Gebremedhin, Ken Yamaura, Chenyang Zhang, Johan Bylund, Raymond C. Koehler, David R. Harder   +5 more
openalex   +1 more source

Tet controls axon guidance in early brain development through glutamatergic signaling

iScience
Summary: Mutations in ten-eleven translocation (TET) proteins are associated with human neurodevelopmental disorders. We find a function of Tet in regulating Drosophila early brain development.
Hiep Tran, Le Le, Badri Nath Singh, Joseph Kramer, Ruth Steward   +4 more
doaj   +1 more source

Meclizine and metabotropic glutamate receptor agonists attenuate severe pain and primary sensory neuron Ca²⁺activity in chemotherapy-induced peripheral neuropathy [PDF]

, 2021
John Shannonhouse, Matteo Bernabucci, Ruben Gomez, Hyeonwi Son, Yan Zhang, Hirotake Ishida, Yu Shin Kim   +6 more
openalex   +1 more source

Scaffold Hopping to Imidazo[1,2‑a]pyrazin-8-one Positive Allosteric Modulators of Metabotropic Glutamate 2 Receptor

ACS Omega, 2021
Ana I. de Lucas, Juan A. Vega, Aránzazu García Molina, María Lourdes Linares, Gary Tresadern, Hilde Lavreysen, Daniel Oehlrich, Andrés A. Trabanco, José M. Cid   +8 more
doaj   +1 more source

The Metabotropic Glutamate 2/3 Receptor Agonist LY379268 Blocked Nicotine-Induced Increases in Nucleus Accumbens Shell Dopamine only in the Presence of a Nicotine-Associated Context in Rats [PDF]

, 2011
Manoranjan S. D’Souza, Matthias E. Liechti, Ana M. Ramirez-Niño, Ronald Kuczenski, Athina Markou   +4 more
openalex   +1 more source

Optogluram-2: a subtype-selective photoswitchable positive allosteric modulator for metabotropic glutamate receptor 4 [PDF]

, 2023
Silvia Panarello, Aleix González-Díez, Alice E. Berizzi, Fanny Malhaire, Roser Borràs‐Tudurí, Xavier Rovira, Laurent Prézeau, Jean‐Philippe Pin, Cyril Goudet, Amadeu Llebaria, Xavier Gómez‐Santacana   +10 more
openalex   +1 more source