Results 141 to 150 of about 52,982 (243)

Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ-46281222. [PDF]

Br J Pharmacol, 2016
Doornbos ML, Pérez-Benito L, Tresadern G, Mulder-Krieger T, Biesmans I, Trabanco AA, Cid JM, Lavreysen H, IJzerman AP, Heitman LH.   +9 more
europepmc   +1 more source

Faculty Opinions recommendation of N-Acetyl-cysteine causes analgesia by reinforcing the endogenous activation of type-2 metabotropic glutamate receptors.

, 2013
Andrea Truini
openalex   +1 more source

Ionic Lock: Functional Role in Activation of Metabotropic Glutamate Receptor 2 [PDF]

Biophysical Journal, 2017
Javier González-Maeso, Diomedes E. Logothetis, Amr Ellaithy, Takeharu Kawano, Yu Xu   +4 more
openaire   +2 more sources

Metabotropic Glutamate Receptor 2 Positive Allosteric Modulators: Closing the Gate on Drug Abuse? [PDF]

Biol Psychiatry, 2015
Johnson KA, Lovinger DM.
europepmc   +1 more source

Cross-signaling in metabotropic glutamate 2 and serotonin 2A receptor heteromers in mammalian cells

Pflügers Archiv: European Journal of Physiology, 2016
L. Baki, M. Fribourg, Jason Younkin, Jose M. Eltit, J. Moreno, Gyu Park, Zhanna V. Vysotskaya, Adishesh K. Narahari, S. Sealfon, J. González-Maeso, D. Logothetis   +10 more
semanticscholar   +1 more source

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Selected for Clinical Evaluation

, 2017
Andrew S. Felts, Alice L. Rodriguez, Anna L. Blobaum, Ryan D. Morrison, Brittney S. Bates, Analisa Thompson Gray, Jerri M. Rook, Mohammed Noor Tantawy, Frank W. Byers, Sichen Chang, Daryl F. Venable, Vincent B. Luscombe, Gilles Tamagnan, Colleen M. Niswender, J. Scott Daniels, Carrie K. Jones, P. Jeffrey Conn, Craig W. Lindsley, Kyle A. Emmitte   +18 more
openalex   +1 more source

The metabotropic glutamate receptor types 2/3 inhibit L-type calcium channels via a pertussis toxin-sensitive G-protein in cultured cerebellar granule cells [PDF]

, 1994
Pascale Chavis, H. Shinozaki, Joël Bockaert, Laurent Fagni   +3 more
openalex   +1 more source

Discovery of 1,5-disubstituted pyridones: a new class of positive allosteric modulators of the metabotropic glutamate 2 receptor.

ACS Chemical Neuroscience, 2010
J. Cid, G. Duvey, P. Cluzeau, V. Nhem, Karim Macary, A. Raux, Nicolas Poirier, J. Muller, C. Boléa, T. Finn, S. Poli, M. Epping-Jordan, Emilie Chamelot, Francis Derouet, Françoise Girard, G. Macdonald, J. A. Vega, A. D. de Lucas, E. Matesanz, H. Lavreysen, María Lourdes Linares, Daniel Oehlrich, J. Oyarzábal, G. Tresadern, A. Trabanco, J. Andrés, E. Le Poul, Hassan Imogai, Robert Lutjens, J. Rocher   +29 more
semanticscholar   +1 more source

Effects of a Calcimimetic Compound and Naturally Activating Mutations on the Human Ca²⁺Receptor and on Ca²⁺Receptor/Metabotropic Glutamate Chimeric Receptors [PDF]

, 2000
Omar M. Hauache, Jianxin Hu, Kausik K. Ray, Rongyuan Xie, Kenneth A. Jacobson, Allen M. Spiegel   +5 more
openalex   +1 more source

Peripheral Group II Metabotropic Glutamate Receptors (mGluR2/3) Regulate Prostaglandin E₂-Mediated Sensitization of Capsaicin Responses and Thermal Nociception [PDF]

, 2002
Dongni Yang, Robert W. Gereau
openalex   +1 more source