The mGlu7 receptor provides protective effects against epileptogenesis and epileptic seizures
Neurobiology of Disease, 2019 Finding new targets to control or reduce seizure activity is essential to improve the management of epileptic patients. We hypothesized that activation of the pre-synaptic and inhibitory metabotropic glutamate receptor type 7 (mGlu7) reduces spontaneous ...
Benoit Girard +14 more
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Norbin
Communicative & Integrative Biology, 2010 Norbin, a neurite-outgrowth promoting protein, has been found to interact with and regulate several membrane proteins, including metabotropic glutamate receptor 5 (mGluR5).
Hong Wang +4 more
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Frontiers in Cellular Neuroscience, 2018 Group I metabotropic glutamate receptors, in particular mGluR5, have been implicated in various forms of synaptic plasticity that are believed to underlie declarative memory.
Sophie Lepannetier +14 more
semanticscholar +1 more source
Journal of Pharmacological Sciences, 2015 The blockade of metabotropic glutamate 5 (mGlu5) receptor has been reported to exert antidepressant effects in several animal models. We previously reported that both ketamine and an mGlu5 receptor antagonist exerted an effect in a novelty-suppressed ...
Kenichi Fukumoto, Shigeyuki Chaki
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Author response: Dissociation of impulsive traits by subthalamic metabotropic glutamate receptor 4
, 2021 Lukasz Piszczek +6 more
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The effects of (RS)‐α‐cyclopropyl‐4‐phosphonophenylglycine ((RS)‐CPPG), a potent and selective metabotropic glutamate receptor antagonist [PDF]
, 1996 Nicholas J. Toms +9 more
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Glutamate Stimulates Local Protein Synthesis in the Axons of Rat Cortical Neurons by Activating α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptors and Metabotropic Glutamate Receptors [PDF]
, 2015 Wei-Lun Hsu +7 more
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PHCCC, a Specific Enhancer of Type 4 Metabotropic Glutamate Receptors, Reduces Proliferation and Promotes Differentiation of Cerebellar Granule Cell Neuroprecursors [PDF]
, 2004 A.M. Canudas +11 more
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Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors? [PDF]
Cell Journal, 2012 Objective: Ecstasy, or 3, 4 (±) methylenedioxymethamphetamine (MDMA), is a potent neurotoxic drug. One of the mechanisms for its toxicity is the secondary release of glutamate.
Rokhsareh Meamar +4 more
doaj