Results 151 to 160 of about 52,301 (266)

Endothelium glutamate receptors in brain pathology. [PDF]

Front Pharmacol
Pirozhkov SV, Vukolova MN, Bulgakova VV, Lutokhina YA, Bolevich SB, Sobolevsky AI, Yelshanskaya MV.   +6 more
europepmc   +1 more source

Glycine Release Is Upregulated by Metabotropic Glutamate Receptor 1 in Mouse Hippocampus. [PDF]

Biomedicines
Raiteri L, Cerminara M, Puliti A, Pittaluga A.   +3 more
europepmc   +1 more source

Discovery of 7-(Pyridin-3-yl)thieno[3,2-<i>b</i>]pyridine-5-carboxamides as Negative Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5. [PDF]

ACS Chem Neurosci
Henderson SH, Ringuette AE, Whomble DL, Capstick RA, Richardson AE, Maurer MA, Billard NB, Lei X, Wilkinson JC, Kethanapalli SH, Cho HP, Rodriguez AL, Niswender CM, Peng W, Rook JM, Chang S, Blobaum AL, Boutaud O, Felts AS, Conn PJ, Lindsley CW, Temple KJ.   +21 more
europepmc   +1 more source

Metabotropic glutamate receptors: Allosteric structural modulation and new treatments for anxiety disorders. [PDF]

Neurosciences (Riyadh)
Zakari MO.
europepmc   +1 more source

Discovery and Preclinical Characterization of 1-Methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1 H -pyrazolo-[3,4- b ]pyrazine (PF470): A Highly Potent, Selective, and Efficacious Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulator

, 2014
Lei Zhang, Gayatri Balan, Gabriela Barreiro, Brian P. Boscoe, Lois K. Chenard, Julie Cianfrogna, Michelle M. Claffey, Laigao Chen, Karen J. Coffman, Susan E. Drozda, Joshua R. Dunetz, Kari R. Fonseca, Paul Galatsis, Sarah Grimwood, John T. Lazzaro, Jessica Mancuso, Emily Miller, Matthew R. Reese, Bruce N. Rogers, Isao Sakurada, Marc B. Skaddan, Deborah L. Smith, Antonia F. Stepan, Patrick Trapa, Jamison B. Tuttle, Patrick R. Verhoest, Daniel P. Walker, Ann S. Wright, Margaret M. Zaleska, Kenneth Zasadny, Christopher L. Shaffer   +30 more
openalex   +1 more source

Computational Identification of Blood-Brain Barrier-Permeant Microbiome Metabolites with Binding Affinity to Neurotransmitter Receptors in Neurodevelopmental Disorders. [PDF]

Molecules
Buendia-Corona RE, Velasco Dey MF, Valencia Robles L, Hernández-Biviano HJ, Hermosillo-Abundis C, Castro-Pastrana LI.   +5 more
europepmc   +1 more source

Discovery and in vitro and in vivo profiles of 4-fluoro-N-[4-[6-(isopropylamino)pyrimidin-4-yl]-1,3-thiazol-2-yl]-N-methylbenzamide as novel class of an orally active metabotropic glutamate receptor 1 (mGluR1) antagonist

, 2009
Atsushi Satoh, Yasushi Nagatomi, Yukari Hirata, Satoru Ito, Gentaroh Suzuki, Toshifumi Kimura, Shunsuke Maehara, Hirohiko Hikichi, Akio Satow, M. Hata, Hisashi Ohta, Hiroshi Kawamoto   +11 more
openalex   +1 more source

Impairment of Group I Metabotropic Glutamate Receptors in the Dorsal Striatum of the R451C-Neuroligin 3 Mouse Model of Autism Spectrum Disorder. [PDF]

J Neurochem
Meringolo M, Montanari M, D'Antoni S, Martella G, El Atiallah I, Ponterio G, Tassone A, Reverte I, Caprioli D, Strimpakos G, Pieroni L, Catania MV, Bonsi P.   +12 more
europepmc   +1 more source

Structure−Activity Relationships Comparing N-(6-Methylpyridin-yl)-Substituted Aryl Amides to 2-Methyl-6-(substituted-arylethynyl)pyridines or 2-Methyl-4-(substituted-arylethynyl)thiazoles as Novel Metabotropic Glutamate Receptor Subtype 5 Antagonists

, 2009
Santosh S. Kulkarni, Mu‐Fa Zou, Jianjing Cao, Jeffrey R. Deschamps, Alice L. Rodriguez, P. Jeffrey Conn, Amy Hauck Newman   +6 more
openalex   +1 more source

Potent and selective pharmacodynamic synergy between the metabotropic glutamate receptor subtype 2–positive allosteric modulator JNJ‐46356479 and levetiracetam in the mouse 6‐Hz (44‐mA) model [PDF]

, 2018
Cameron S. Metcalf, Brian D. Klein, Misty D. Smith, Marc Ceusters, Hilde Lavreysen, Stefan Pype, Nancy Van Osselaer, Roy E. Twyman, H. Steve White   +8 more
openalex   +1 more source