Results 211 to 220 of about 51,960 (263)

Synaptic proteome diversity is shaped by the levels of glutamate receptors and their regulatory proteins. [PDF]

open access: yesNat Commun
Reig-Viader R   +11 more
europepmc   +1 more source

Transcriptomic and Proteomic Changes in the Brain Along with Increasing Phenotypic Severity in a Rat Model of Neonatal Hyperbilirubinemia. [PDF]

open access: yesInt J Mol Sci
Llido JP   +11 more
europepmc   +1 more source

WONOEP XVII appraisal: Targeting network excitability beyond the synapse -Neurotransmitter, ionic, and electro -diffusions. [PDF]

open access: yesEpilepsia
Magloire V   +9 more
europepmc   +1 more source

Immunohistological Studies of Metabotropic Glutamate Receptor Subtype 6-Deficient Mice Show No Abnormality of Retinal Cell Organization and Ganglion Cell Maturation

open access: yesImmunohistological Studies of Metabotropic Glutamate Receptor Subtype 6-Deficient Mice Show No Abnormality of Retinal Cell Organization and Ganglion Cell Maturation
openaire  

Impaired behavioral suppression by light in metabotropic glutamate receptor subtype 6-deficient mice

open access: closedNeuroscience, 2000
The metabotropic glutamate receptor subtype 6 is localized on the dendrites of ON bipolar cells in mammalian retina, and is responsible for synaptic transmission from photoreceptors to ON bipolar cells. We have previously provided electrophysiological evidence that metabotropic glutmate receptor subtype 6-deficient mice have an impairment in the ON ...
Motoharu Takao   +7 more
openalex   +3 more sources

Blockade of metabotropic glutamate receptor 5 attenuates axonal degeneration in 6-hydroxydopamine-induced model of Parkinson's disease

Molecular and Cellular Neuroscience, 2021
Although there are numerous strategies to counteract the death of dopaminergic neurons in Parkinson's disease (PD), there are currently no treatments that delay or prevent the disease course, indicating that early protective treatments are needed.
Jian-Nan, Zhang   +5 more
openaire   +2 more sources

A unilateral 6-hydroxydopamine lesion decreases the expression of metabotropic glutamate receptors in rat substantia nigra

Neuroscience Letters, 2003
Loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) leads to augmentation of glutamatergic activity in the subthalamic nucleus (STN). Moreover, antagonizing excitotoxicity has yielded mostly symptomatic improvements in experimental animals of PD.
Bing, Gu, Ying-Dong, Zhang, Gang, Hu
openaire   +3 more sources

The metabotropic glutamate receptor antagonist 2-methyl-6-(phenylethynyl)-pyridine (MPEP) blocks fear conditioning in rats

Neuropharmacology, 2001
Glutamate receptors play an essential role in fear-related learning and memory. The present study was designed to assess the role of the group I metabotropic glutamate receptor (mGluR) subtype 5 in the acquisition and retrieval of conditioned fear in rats.
B, Schulz   +5 more
openaire   +2 more sources

Neuroprotective effects of metabotropic glutamate receptor ligands in a 6‐hydroxydopamine rodent model of Parkinson's disease

European Journal of Neuroscience, 2005
AbstractIncreasing evidence implicates glutamate‐mediated excitotoxicity as a contributory factor in dopaminergic cell death in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD). Previous studies have suggested that metabotropic glutamate receptor (mGluR) ligands are neuroprotective against excitotoxicity in vitro.
A C, Vernon   +5 more
openaire   +2 more sources

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