Results 211 to 220 of about 51,960 (263)
Synaptic proteome diversity is shaped by the levels of glutamate receptors and their regulatory proteins. [PDF]
Reig-Viader R +11 more
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Transcriptomic and Proteomic Changes in the Brain Along with Increasing Phenotypic Severity in a Rat Model of Neonatal Hyperbilirubinemia. [PDF]
Llido JP +11 more
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WONOEP XVII appraisal: Targeting network excitability beyond the synapse -Neurotransmitter, ionic, and electro -diffusions. [PDF]
Magloire V +9 more
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openaire
Impaired behavioral suppression by light in metabotropic glutamate receptor subtype 6-deficient mice
The metabotropic glutamate receptor subtype 6 is localized on the dendrites of ON bipolar cells in mammalian retina, and is responsible for synaptic transmission from photoreceptors to ON bipolar cells. We have previously provided electrophysiological evidence that metabotropic glutmate receptor subtype 6-deficient mice have an impairment in the ON ...
Motoharu Takao +7 more
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Molecular and Cellular Neuroscience, 2021
Although there are numerous strategies to counteract the death of dopaminergic neurons in Parkinson's disease (PD), there are currently no treatments that delay or prevent the disease course, indicating that early protective treatments are needed.
Jian-Nan, Zhang +5 more
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Although there are numerous strategies to counteract the death of dopaminergic neurons in Parkinson's disease (PD), there are currently no treatments that delay or prevent the disease course, indicating that early protective treatments are needed.
Jian-Nan, Zhang +5 more
openaire +2 more sources
Neuroscience Letters, 2003
Loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) leads to augmentation of glutamatergic activity in the subthalamic nucleus (STN). Moreover, antagonizing excitotoxicity has yielded mostly symptomatic improvements in experimental animals of PD.
Bing, Gu, Ying-Dong, Zhang, Gang, Hu
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Loss of dopaminergic neurons in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD) leads to augmentation of glutamatergic activity in the subthalamic nucleus (STN). Moreover, antagonizing excitotoxicity has yielded mostly symptomatic improvements in experimental animals of PD.
Bing, Gu, Ying-Dong, Zhang, Gang, Hu
openaire +3 more sources
Neuropharmacology, 2001
Glutamate receptors play an essential role in fear-related learning and memory. The present study was designed to assess the role of the group I metabotropic glutamate receptor (mGluR) subtype 5 in the acquisition and retrieval of conditioned fear in rats.
B, Schulz +5 more
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Glutamate receptors play an essential role in fear-related learning and memory. The present study was designed to assess the role of the group I metabotropic glutamate receptor (mGluR) subtype 5 in the acquisition and retrieval of conditioned fear in rats.
B, Schulz +5 more
openaire +2 more sources
European Journal of Neuroscience, 2005
AbstractIncreasing evidence implicates glutamate‐mediated excitotoxicity as a contributory factor in dopaminergic cell death in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD). Previous studies have suggested that metabotropic glutamate receptor (mGluR) ligands are neuroprotective against excitotoxicity in vitro.
A C, Vernon +5 more
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AbstractIncreasing evidence implicates glutamate‐mediated excitotoxicity as a contributory factor in dopaminergic cell death in the substantia nigra pars compacta (SNc) in Parkinson's disease (PD). Previous studies have suggested that metabotropic glutamate receptor (mGluR) ligands are neuroprotective against excitotoxicity in vitro.
A C, Vernon +5 more
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