Results 71 to 80 of about 44,093 (262)
Intrinsic ON Responses of the Retinal OFF Pathway Are Suppressed by the ON Pathway
Journal of Neuroscience, 2006 Parallel ON and OFF pathways conduct visual signals from bipolar cells in the retina to higher centers in the brain. ON responses are thought to originate by exclusive use of metabotropic glutamate receptor 6 (mGluR6) expressed in retinal ON bipolar ...
R. Rentería +5 more
semanticscholar +1 more source
Journal of Nuclear Medicine, 2020 Animal models of alcohol dependence and relapse demonstrate an important role of the glutamatergic system, in particular, cerebral metabotropic glutamate receptor 5 (mGluR5).
J. Ceccarini +6 more
semanticscholar +1 more source
Medicine Bulletin, EarlyView.ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao +6 more
wiley +1 more source
Frontiers in Immunology, 2022 Autoantibodies to metabotropic glutamate receptor 5 (mGluR5) are known to be the cause of autoimmune encephalitis, particularly limbic encephalitis, closely related to Hodgkin’s lymphoma (HL).
Weiqian Yan +4 more
doaj +1 more source
Journal of Nuclear Medicine, 2020 Targeted radionuclide therapy (TRT) targeting oncoproteins facilitates the delivery of therapeutic radionuclides to tumor tissues with high precision.
Lin Xie +12 more
semanticscholar +1 more source
Could MDMA Promote Stemness Characteristics in Mouse Embryonic Stem Cells via mGlu5 Metabotropic Glutamate Receptors? [PDF]
Cell Journal, 2012 Objective: Ecstasy, or 3, 4 (±) methylenedioxymethamphetamine (MDMA), is a potent neurotoxic drug. One of the mechanisms for its toxicity is the secondary release of glutamate.
Rokhsareh Meamar +4 more
doaj
Effects of Oleuropein on Depression Caused by Chronic Stress in Mice
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2021 Background and Objectives: Depression is still one of challenging, and widely encountered disorders with complex etiology. Recently the role of healthy diet and olive oil in ameliorating depression has been claimed. This study was designed to explore the
Maedeh Jafari +2 more
doaj
The activation of group II metabotropic glutamate receptors protects neonatal rat brains from oxidative stress injury after hypoxia-ischemia. [PDF]
PLoS ONE, 2018 Birth asphyxia resulting in brain hypoxia-ischemia (H-I) can cause neonatal death or lead to persistent brain damage. Recent investigations have shown that group II metabotropic glutamate receptor (mGluR2/3) activation can provide neuroprotection against
Ewelina Bratek +3 more
doaj +1 more source
A comprehensive review on adaptive plasticity and recovery mechanisms post‐acquired brain injury
Neuroprotection, EarlyView.This figure illustrates the dynamic process of neurogenesis following brain injury, focusing on the roles of neural stem and progenitor cells at the injury site. Key mechanisms include axonal sprouting, synaptogenesis, dendritic remodeling, and brain‐derived neurotrophic factor signaling via TrkB receptors.
Ravi Kumar Rajan
wiley +1 more source
ASN Neuro, 2018 Levodopa (L-DOPA) is still the most effective drug for the treatment of Parkinson’s disease (PD). However, the long-term therapy often triggers L-DOPA-induced dyskinesia (LID).
Yixian Huang +6 more
doaj +1 more source