Results 121 to 130 of about 114,351 (281)
Structural insights into the activation of metabotropic glutamate receptors
Nature, 2019 A. Koehl +16 more
semanticscholar +1 more source
European Journal of Neurology, Volume 32, Issue 8, August 2025.This monocentric observational study investigates a fixed combination of acetyl‐L‐carnitine, palmitoylethanolamide, and alpha‐lipoic acid in 48 patients with acute low back pain. Over 8 weeks, treatment led to significant reductions in neuropathic pain scores, decreased NSAID consumption, and improvements in quality of life, supporting its potential ...
Mattia Cominacini +5 more
wiley +1 more source
Molecular, functional, and pharmacological characterization of the metabotropic glutamate receptor type 5 splice variants: comparison with mGluR1 [PDF]
, 1995 C. Joly +5 more
openalex +1 more source
Metabotropic Glutamate Receptors and Epileptiform Bursting
Epilepsy Currents, 2002 Differential Roles for mGluR1 and mGluR5 in the Persistent Prolongation of Epileptiform Bursts Merlin LR J Neurophysiol 2002;87:621–625 Purpose Transient activation of group I metabotropic glutamate receptors (mGluRs) with the selective agonist (S)-3,5-dihydroxyphenylglycine (DHPG) produces persistent prolongation of epileptiform bursts in guinea ...
openaire +3 more sources
Fundamental &Clinical Pharmacology, Volume 39, Issue 4, August 2025.ABSTRACT In the 1950s–60s, serotonergic psychedelic drugs were studied as potential adjuvants to psychotherapy to treat addiction and alcoholism. However, starting in the 70s, preclinical and clinical studies on psychedelics stopped for decades because legislation controlled its recreational use, citing their hallucinogenic and psychotomimetic effects,
Makiath Adebo +9 more
wiley +1 more source
The Implication of Glial Metabotropic Glutamate Receptors in Alzheimer's Disease. [PDF]
Curr Neuropharmacol, 2023 de Lima IBQ, Ribeiro FM.
europepmc +1 more source
Axon/Dendrite Targeting of Metabotropic Glutamate Receptors by Their Cytoplasmic Carboxy-Terminal Domains [PDF]
, 1999 Julia Nash Stowell, Ann Marie Craig
openalex +1 more source
Hallucinogens: mechanisms and medical complications [PDF]
, 2013 Thesis (M.A.)--Boston UniversityHallucinogens are drugs that alter consciousness by distorting primarily auditory and visual perception but they can affect any sensory system. Hallucinogens also affect judgment, orientation, memory, or emotion.
Chan, Ryan Harry Alexander
core +1 more source
Leveraging Fiber Photometry to Decipher Neural Circuits Underlying Anxiety in Mice
Fundamental &Clinical Pharmacology, Volume 39, Issue 5, October 2025.ABSTRACT Anxiety disorders rank among the most prevalent mental health conditions worldwide, significantly affecting patients' lives. They are frequently comorbid with other psychiatric disorders, often exacerbating their severity. Current pharmacological treatments; selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines, remain limited in
Salma R. Abdennebi +4 more
wiley +1 more source
The Role of Neuroglial Metabotropic Glutamate Receptors in Alzheimer's Disease. [PDF]
Curr Neuropharmacol, 2023 Abd-Elrahman KS +2 more
europepmc +1 more source