Results 131 to 140 of about 62,416 (271)

Lifelong Impact of Prenatal Stress: Exacerbated Memory Impairments and Gene Expression Changes Under Adult Chronic Stress

Brain and Behavior, Volume 15, Issue 12, December 2025.
ABSTRACT Introduction Chronic stress can have significant impacts on both physical and mental health, including affecting learning and memory processes. Research has shown that exposure to stress during prenatal and neonatal stages can have long‐lasting effects on individuals. The objective of this study is to investigate how prenatal stress influences
Manijeh Dogani, Nayere Askari, Mohammad‐Reza Vaez‐Mahdavi   +2 more
wiley   +1 more source

Interplay between metabotropic glutamate type 4 and adenosine type 1 receptors modulate synaptic transmission in the cerebellar cortex

Frontiers in Pharmacology
The synapses between parallel fibers and Purkinje cells play a pivotal role in cerebellar function. They are intricately governed by a variety of presynaptic receptors, notably by type 4 metabotropic glutamate (mGlu4) receptors and type 1 adenosine (A1 ...
Simon Bossi, Hervé Daniel, Heather McLean   +2 more
doaj   +1 more source

Direct Interaction Enables Cross-talk between Ionotropic and Group I Metabotropic Glutamate Receptors [PDF]

, 2008
Julie Perroy, Fabrice Raynaud, Vincent Homburger, Marie-Claude Rousset, Ludovic Telley, Joël Bockaert, Laurent Fagni   +6 more
openalex   +1 more source

Functional Brain Connectivity Patterns of Headache–Mental Disorder Comorbidity in Patients With Migraine

CNS Neuroscience &Therapeutics, Volume 31, Issue 12, December 2025.
This study identified the functional brain connectivity patterns that were correlated with headache and mental conditions in migraineurs and then detected that those features had potential to discriminate patients from healthy controls, stratify patients into subgroups, and predict treatment outcomes.
Tao Yin, Zilei Tian, Lei Lan, Zhengjie Li, Mailan Liu, Yujie Gao, Fanrong Liang, Fang Zeng   +7 more
wiley   +1 more source

Localization and Expression of Group I Metabotropic Glutamate Receptors in the Mouse Striatum, Globus Pallidus, and Subthalamic Nucleus: Regulatory Effects of MPTP Treatment and Constitutive Homer Deletion [PDF]

, 2007
Masaaki Kuwajima, Marlin H. Dehoff, Teiichi Furuichi, Paul F. Worley, Randy A. Hall, Yoland Smith   +5 more
openalex   +1 more source

Seizures beget more than seizures: Understanding the cellular, structural, individual and societal impact of seizures in epilepsy

Epilepsia Open, Volume 10, Issue 6, Page 1762-1773, December 2025.
Abstract Epilepsy is primarily defined by the repetitive occurrence of seizures, but the full impact of seizures extends beyond these episodic events. Seizures themselves cause changes at the cellular, network, and systemic levels in individual patients with epilepsy and may contribute to the progressive nature of the disease in some patients. Seizures
Matthew C. Walker, Marian Galovic, Elena Álvarez‐Barón, Adam Strzelczyk   +3 more
wiley   +1 more source

Metabotropic Glutamate Receptors [PDF]

Journal of Biological Chemistry, 2015
James Dillon, Christopher J. Franks, Caitriona Murray, Richard J. Edwards, Fernando Calahorro, Takeshi Ishihara, Isao Katsura, Lindy Holden-Dye, Vincent O'Connor   +8 more
openaire   +1 more source

Neurotransmitters and Immunity: Molecular Mechanisms, Biological Functions, Diseases, and Potential Therapeutic Targets

MedComm, Volume 6, Issue 12, December 2025.
Role of neurotransmitters in multiple pathological processes. Various neurotransmitters, including ACh, EPI, NE, 5‐HT, histamine, DA, glutamate, GABA, and neuropeptides participate in regulating key pathological events, including tumor proliferation, tumor migration, remodeling of the immune microenvironment, and the development of NDDs and ...
Gege Li, Fangfang Li, Yang Tang, Siyu Guo, Yihan Yao, Yuan Fang, Bicheng Zhang, Yu Jiang, Jing Wang, Dang Wu, Jianxia Cheng, Zhihui Huang, Zengfeng Xin, Ting Zhang   +13 more
wiley   +1 more source

Metabotropic Glutamate Receptor 5 Antagonism with Fenobam [PDF]

, 2011
Michael C. Montana, Beth A. Conrardy, Laura F. Cavallone, Benedict J. Kolber, Lesley K. Rao, Suellen Greco, Robert W. Gereau   +6 more
openalex   +1 more source

Oligodendrocyte Precursor Cells in Demyelination Repair: Mechanisms, Crosstalk, and Therapeutic Frontiers

Medicine Bulletin, Volume 1, Issue 2, Page 104-120, December 2025.
ABSTRACT In multiple sclerosis (MS), demyelination is often accompanied by severe motor and cognitive disability. Remyelination is the process of regenerating new myelin sheath on impaired axons, which is typically carried out by oligodendrocyte precursor cells (OPCs).
Zixin Gao, Mengdi Guo, Kehan Chen, Mei‐Ling Jiang, Lin‐ming Zhang, Lorenzo Di Cesare Mannelli, Cun‐jin Zhang   +6 more
wiley   +1 more source