Results 131 to 140 of about 114,351 (281)

Metabotropic glutamate receptors trigger postsynaptic protein synthesis.

, 1993
Ivan Jeanne Weiler, William T. Greenough
openalex   +1 more source

Functional Switch from Facilitation to Inhibition in the Control of Glutamate Release by Metabotropic Glutamate Receptors [PDF]

, 1998
I. Herrero, María Teresa Miras‐Portugal, José Sánchez‐Prieto   +2 more
openalex   +1 more source

MGlu5 Dependent Mitochondrial Translocation of PKCδ: A Mechanism Raising Astrocytic Oxidative Metabolism in Response to Extracellular Glutamate

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
The observations suggest a new mechanism, the mGluR5/PKCδ/PDH axis by which extracellular glutamate can raise oxidative metabolism in astrocytes, in response to rapidly increasing energy demands, such as in the liver or skeletal muscle. It appears that the plethora of astrocytic mitochondria maintain only a basal level of oxidative metabolism during ...
Kiavasch M. N. Farid, Rodrigo Lerchundi, Christine R. Rose, Amin Derouiche   +3 more
wiley   +1 more source

EpileptogenesisIn VivoEnhances the Sensitivity of Inhibitory Presynaptic Metabotropic Glutamate Receptors in Basolateral Amygdala NeuronsIn Vitro [PDF]

, 1997
Volker Neugebauer, N. Bradley Keele, Patricia Shinnick‐Gallagher   +2 more
openalex   +1 more source

From Neurotransmission to Retinal Pathophysiology: Unraveling the Role of GABA Receptors in Retinal Disease Progression

Journal of Neurochemistry, Volume 169, Issue 8, August 2025.
GABA receptors, widely expressed in the retina, play a key role in lateral inhibition and synaptic regulation. Emerging evidence links their dysregulation to retinal diseases such as diabetic retinopathy, retinitis pigmentosa, glaucoma, and age‐related macular degeneration.
Alan E. Medina Arellano, Jesus Silvestre Albert‐Garay, Nadia Flores Huerta, Karla Tovar Hernández, Matilde Ruiz‐Cruz, Lenin Ochoa‐de la Paz   +5 more
wiley   +1 more source

The Lateral Metalation of Isoxazolo[3,4-d]pyridazinones towards Hit-to-Lead Development of Selective Positive Modulators of Metabotropic Glutamate Receptors. [PDF]

Molecules, 2023
Gates CA, Backos DS, Reigan P, Natale NR.   +3 more
europepmc   +1 more source

Activation of the metabotropic glutamate receptor attenuates N-methyl-D-aspartate neurotoxicity in cortical cultures.

, 1991
Jae‐Young Koh, Elizabeth E. Palmer, CW Cotman   +2 more
openalex   +1 more source

Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus [PDF]

, 1996
Domenico E. Pellegrini‐Giampietro, Serenella Albani Torregrossa, Flavio Moroni   +2 more
openalex   +1 more source

Non‐ionotropic NMDAR signalling activates Panx1 to induce P2X4R‐dependent long‐term depression in the hippocampus

The Journal of Physiology, Volume 603, Issue 15, Page 4367-4381, 1 August 2025.
Abstract figure legend Stimulation of the Shaffer collateral pathway at 3 Hz activates non‐ionotropic NMDA receptors. This subsequently leads to Src kinase mediated phosphorylation of pannexin‐1 (Panx1), which releases ATP from the postsynaptic cell. ATP acts as a ligand for P2X4 receptors to induce long‐term depression (LTD). Abstract In recent years,
Allison C. Nielsen, Connor L. Anderson, Carina Ens, Andrew K. J. Boyce, Roger J. Thompson   +4 more
wiley   +1 more source

Attenuation of Stimulated Accumbal Dopamine Release by NMDA Is Mediated through Metabotropic Glutamate Receptors. [PDF]

ACS Chem Neurosci, 2023
Spencer FSE, Glodkowska M, Sebold AI, Yavas E, Young AMJ.   +4 more
europepmc   +1 more source