Results 231 to 240 of about 114,351 (281)

Correction to: Group I and group II metabotropic glutamate receptors are upregulated in the synapses of infant rats prenatally exposed to valproic acid. [PDF]

open access: yesPsychopharmacology (Berl)
D'Antoni S   +9 more
europepmc   +1 more source

Preso1 dynamically regulates group I metabotropic glutamate receptors

open access: yesNature Neuroscience, 2012
Jia-hua Hu   +13 more
semanticscholar   +1 more source

Homer Binds a Novel Proline-Rich Motif and Links Group 1 Metabotropic Glutamate Receptors with IP3 Receptors

open access: yesNeuron, 1998
J. Tu   +7 more
semanticscholar   +1 more source

Structural plasticity of perisynaptic astrocyte processes involves ezrin and metabotropic glutamate receptors

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2011
M. Lavialle   +5 more
semanticscholar   +1 more source

Pharmacology and functions of metabotropic glutamate receptors.

Annual Review of Pharmacology and Toxicology, 1997
▪ Abstract  In the mid to late 1980s, studies were published that provided the first evidence for the existence of glutamate receptors that are not ligand-gated cation channels but are coupled to effector systems through GTP-binding proteins. Since those initial reports, tremendous progress has been made in characterizing these metabotropic glutamate ...
Conn Pj, J. Pin
semanticscholar   +4 more sources

The metabotropic glutamate receptors: Structure and functions

Neuropharmacology, 1995
Glutamate is the main excitatory neurotransmitter in the brain. For many years it has been considered to act only on ligand-gated receptor channels--termed NMDA, AMPA and kainate receptors--involved in the fast excitatory synaptic transmission. Recently, glutamate has been shown to regulate ion channels and enzymes producing second messengers via ...
J. Pin, R. Duvoisin
semanticscholar   +3 more sources

Dynamics and modulation of metabotropic glutamate receptors.

Current Opinion in Pharmacology, 2015
The metabotropic glutamate receptors (mGluRs) are glutamate-activated G protein-coupled receptors widely expressed in the central nervous system. The eight mGluRs subtypes modulate transmission at many synapses, and are interesting therapeutic targets for the treatment of many neurological and psychiatric diseases.
P. Rondard, J. Pin
semanticscholar   +4 more sources

A family of metabotropic glutamate receptors

Neuron, 1992
Three cDNA clones, mGluR2, mGluR3, and mGluR4, were isolated from a rat brain cDNA library by cross-hybridization with the cDNA for a metabotropic glutamate receptor (mGluR1). The cloned receptors show considerable sequence similarity with mGluR1 and possess a large extracellular domain preceding the seven putative membrane-spanning segments. mGluR2 is
Y. Tanabe   +4 more
semanticscholar   +4 more sources

International Union of Basic and Clinical Pharmacology. CXI. Pharmacology, Signaling, and Physiology of Metabotropic Glutamate Receptors

Pharmacological Reviews, 2020
Metabotropic glutamate (mGlu) receptors respond to glutamate, the major excitatory neurotransmitter in the mammalian brain, mediating a modulatory role that is critical for higher-order brain functions such as learning and memory.
K. Gregory, C. Goudet
semanticscholar   +1 more source

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