Results 71 to 80 of about 59,784 (305)
Glutamate, GABA and acetylcholine signaling components in the lamina of the Drosophila visual system. [PDF]
PLoS ONE, 2008 Synaptic connections of neurons in the Drosophila lamina, the most peripheral synaptic region of the visual system, have been comprehensively described.
Agata Kolodziejczyk +3 more
doaj +1 more source
Metabotropic glutamate receptor agonists for schizophrenia [PDF]
British Journal of Psychiatry, 2008 SummaryA drug acting at metabotropic glutamate receptors has recently been reported to be an effective antipsychotic, breaking the rule that only dopamine receptor-blocking drugs have this property. The finding complements accumulating evidence that glutamatergic abnormalities are important in the pathophysiology of schizophrenia.
openaire +2 more sources
Movement Disorders, EarlyView.Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico +14 more
wiley +1 more source
Metabotropic Glutamate Receptor Activation in Cerebelar Purkinje Cells as Substrate for Adaptive Timing of the Classicaly Conditioned Eye Blink Response [PDF]
, 1995 To understand how the cerebellum adaptively times the classically conditioned nictitating membrane response (NMR), a model of the metabotropic glutamate receptor (mGluR) second messenger system in cerebellar Purkinje cells is constructed.
Bullock, Daniel +2 more
core +1 more source
Brazilian Journal of Medical and Biological Research, 1998 The changes in mean arterial pressure (MAP) and heart rate (HR) in response to the activation of metabotropic receptors in the nucleus tractus solitarii (NTS) with trans-(±)-1-amino-1,3-cyclopentanedicarboxylic acid (trans-(±)-ACPD) were evaluated in ...
B.H. Machado, L.G.H. Bonagamba
doaj +1 more source
PLoS ONE, 2021 Crustaceans are major constituents of aquatic ecosystems and, as such, changes in their behavior and the structure and function of their bodies can serve as indicators of alterations in their immediate environment, such as those associated with climate ...
Jonathan L Crooke-Rosado +4 more
doaj +1 more source
Activation requirements for metabotropic glutamate receptors [PDF]
Neuroscience Letters, 2013 It has been common experimentally to use high frequency, tetanic, stimulation to activate metabotropic glutamate receptors (mGluRs) in cortex and thalamus. To determine what type of stimulation is actually necessary to activate mGluRs we examined the effects of varying stimulation duration and intensity on activating mGluR responses.
S. Murray Sherman +2 more
openaire +3 more sources
Recent Developments in the Optical Control of Adrenergic Signaling
Medicinal Research Reviews, EarlyView.ABSTRACT Adrenoceptors (ARs) play a vital role in various physiological processes and are key therapeutic targets. The advent of optical control techniques, including optogenetics and photopharmacology, offers the potential to modulate AR signaling with precise temporal and spatial resolution. In this review, we summarize the latest advancements in the
Shuang Shi +4 more
wiley +1 more source
Modulation of Synaptic Transmission by Metabotropic Glutamate Receptors and Endocannabinoid Signaling [PDF]
, 2006 Metabotropic glutamate receptors (mGluRs) are distributed throughout the central nervous system and play important roles in the modulation of synaptic transmission.
Nagaraja, R.Y. (Raghavendra)
core +2 more sources
Oxygen/Glucose deprivation induces a reduction in synaptic AMPA receptors on hippocampal CA3 neurons mediated by mGluR1 and adenosine A3 receptors [PDF]
, 2011 Hippocampal CA1 pyramidal neurons are highly sensitive to ischemic damage, whereas neighboring CA3 pyramidal neurons are less susceptible. It is proposed that switching of AMPA receptor (AMPAR) subunits on CA1 neurons during an in vitro model of ischemia,
Cimarosti, Helena +5 more
core +1 more source