Results 71 to 80 of about 503,920 (237)

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

Advanced Science, EarlyView.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun, Teng Ma, Hao Jin, Zelong Li, Yi Cheng, Jingjin Li, Lai‐Yu Kwok, Zhihong Sun   +7 more
wiley   +1 more source

ATLAS: a Snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence data

BMC Bioinformatics, 2020
Background Metagenomics studies provide valuable insight into the composition and function of microbial populations from diverse environments; however, the data processing pipelines that rely on mapping reads to gene catalogs or genome databases for ...
Silas Kieser, Joseph Brown, Evgeny M. Zdobnov, Mirko Trajkovski, Lee Ann McCue   +4 more
doaj   +1 more source

KEMET – A python tool for KEGG Module evaluation and microbial genome annotation expansion

Computational and Structural Biotechnology Journal, 2022
Background: The rapid accumulation of sequencing data from metagenomic studies is enabling the generation of huge collections of microbial genomes, with new challenges for mapping their functional potential.
Matteo Palù, Arianna Basile, Guido Zampieri, Laura Treu, Alessandro Rossi, Maria Silvia Morlino, Stefano Campanaro   +6 more
doaj   +1 more source

Novel insights into the pig gut microbiome using metagenome-assembled genomes

Microbiology Spectrum, 2022
Abstract Pigs are among the most numerous and intensively farmed food-producing animals in the world. The gut microbiome plays an important role in the health and performance of swine and changes rapidly after weaning.
Devin B. Holman, Arun Kommadath, Jeffrey P. Tingley, D. Wade Abbott   +3 more
openaire   +3 more sources

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

Advanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai, Qinyong You, Gao Si, Daole Hu, Ao Sun, Shilong Su, Ruideng Wang, Jixing Fan, Shan Gao, Tengjiao Zhu, Chun‐Li Song, Fang Zhou, Yang Lv   +12 more
wiley   +1 more source

Augmenting microbial phylogenomic signal with tailored marker gene sets

Nature Communications
Phylogenetic marker genes are traditionally selected from a fixed collection of whole genomes representing major microbial phyla, covering only a small fraction of gene families.
Henry Secaira-Morocho, Xiaofang Jiang, Qiyun Zhu   +2 more
doaj   +1 more source

500 metagenome-assembled microbial genomes from 30 subtropical estuaries in South China

, 2021
500 metagenome-assembled microbial genomes from 30 subtropical estuaries in South ...
Peng Xu (12540686), Jiayi Gong (12540683), Lei Zhou (10910547), Xiande Huang (12540688), Shihui Huang (12540689)   +4 more
core   +1 more source

Metagenome assembled genomes of Alnus viridis spp. Fruticose nodules

, 2023
Table1. Sequencing output from nodule metagenomes Table2. Quality metrics for metagenome assembled genomes of Alnus viridis spp. Fruticose nodules.
Neslihan Tas (12964601)
core   +1 more source

Genomes from uncultivated prokaryotes: a comparison of metagenome-assembled and single-amplified genomes

Background: Prokaryotes dominate the biosphere and regulate biogeochemical processes essential to all life. Yet, our knowledge about their biology is for the most part limited to the minority that has been successfully cultured.
Bertilsson, Stefan, Divne, Anna-Maria, Karlsson, Christofer M.G., Homa, Felix, Bergin, Claudia, Lindh, Markus V., Andersson, Anders F., Pinhassi, Jarone, Alneberg, Johannes, Hugerth, Luisa W., Ettema, Thijs JG   +10 more
core   +4 more sources

Metagenomic comparison of gut communities between wild and captive Himalayan griffons

Frontiers in Veterinary Science
IntroductionHimalayan griffons (Gyps himalayensis), known as the scavenger of nature, are large scavenging raptors widely distributed on the Qinghai-Tibetan Plateau and play an important role in maintaining the balance of the plateau ecosystem.
You Wang, You Wang, Jundie Zhai, Jundie Zhai, Boyu Tang, Boyu Tang, Yonggang Dong, Yonggang Dong, Shengzhen Sun, Shunfu He, Wenxin Zhao, Zhuoma Lancuo, Qiangqiang Jia, Wen Wang   +13 more
doaj   +1 more source