Results 161 to 170 of about 140,210 (264)

Majorbio Cloud 2026 Update: An End‐to‐End Solution for Proteomics Research

open access: yesiMetaMed, EarlyView.
The recent upgrade of Majorbio Cloud facilitates a more streamlined and accurate research process, aiding researchers across the various proteomics subfields. Furthermore, it propels the advancement of multi‐layered, multi‐omics scientific investigations centered around proteins.
Caiping Shi   +17 more
wiley   +1 more source

Fast and accurate taxonomic domain assignment of short metagenomic reads using BBERT. [PDF]

open access: yesNucleic Acids Res
Alekhin D   +6 more
europepmc   +1 more source

Addressing the Abundance Paradox Through Topology‐Guided Graph Learning for Cross‐Cohort Classification of Type 2 Diabetes

open access: yesiMetaMed, EarlyView.
By shifting from highly variable taxonomic abundance to conserved ecological network topologies, our Dual‐Stream Graph Attention Network (DS‐GAT‐CP) resolves the “abundance paradox,” enabling highly accurate and cross‐regionally robust non‐invasive screening for Type 2 Diabetes. ABSTRACT Gut microbiome‐based machine learning models for Type 2 Diabetes (
Changjian Wu   +4 more
wiley   +1 more source

Nanopore metagenomic sequencing links clinically relevant resistance determinants to pathogens. [PDF]

open access: yesMicrob Genom
Ürel H   +14 more
europepmc   +1 more source

Chronic Prostatitis/Chronic Pelvic Pain Syndrome: Research Progress and Precision Diagnosis‐Therapy Under the Integrated Neuro–Immune–Metabolic–Microbiota Axis Framework

open access: yesiMetaMed, EarlyView.
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is increasingly recognized as a systemic disorder rather than a purely local prostate disease. The diagram illustrates the transition from the traditional local prostate‐centered model to a multi‐axis systemic framework involving clinical heterogeneity, local prostatic inflammation, systemic ...
Kun Wang   +10 more
wiley   +1 more source

Function‐centered back‐tracing refines obesity‐associated gut microbiome signals beyond abundance‐based profiling

open access: yesiMetaOmics, EarlyView.
By integrating taxonomic and functional profiling of 1543 adult gut metagenomes, this study identified microbial taxa and enzymatic functions associated with increasing Body Mass Index. Function‐centered taxonomic back‐tracing of branched‐chain amino acid transaminase, nucleotide diphosphatase, and phosphatidylserine decarboxylase revealed only limited
Silvia Petraro   +6 more
wiley   +1 more source

Gut microbiome seasonality is associated with dietary plasticity and coexistence in three sympatric Pamir ungulates

open access: yesiMetaOmics, EarlyView.
This graphical abstract outlines a multi‐omics framework investigating the seasonal dietary composition and gut microbial communities of three coexisting ungulate species inhabiting the extreme high‐altitude Pamir Plateau (Ovis ammon polii, Capra sibirica, and Pseudois nayaur). By integrating dietary DNA metabarcoding, 16S rRNA gene sequencing, shotgun
Dilala Tuoliu   +8 more
wiley   +1 more source

ExMODE: A comprehensive resource for extremophile genomic and functional exploration

open access: yesiMetaOmics, EarlyView.
ExMODE (https://db.genomics.cn/exmode/) integrates 3518 samples to build a unified extremophile resource, which hosts 1.35 billion habitat‐specific non‐redundant genes, 5.25 million representative protein structures, 67,026 metagenome‐assembled genomes (MAGs), and 164,132 biosynthetic gene clusters (BGCs). By combining sequence‐, structure‐, and genome‐
Denghui Li   +30 more
wiley   +1 more source

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