A fast workflow to explore active enzymes from environmental samples through functional metagenomics. [PDF]
Muammar A +5 more
europepmc +1 more source
Uric Acid in Metabolic Dysfunction‐Associated Steatotic Liver Disease
MASLD is the most prevalent chronic liver disease worldwide, yet effective pharmacological treatments remain limited. Hyperuricemia is now recognized as a key driver of hepatic steatosis, inflammation, and fibrosis, with elevated serum uric acid levels independently predicting hepatocellular carcinoma and liver‐related mortality.
Rong Wang +5 more
wiley +1 more source
Diagnostic sensitivity and specificity of metagenomic sequencing and qPCR for detection of viruses associated with bovine respiratory disease estimated using Bayesian latent class models. [PDF]
Donbraye E +10 more
europepmc +1 more source
Exploring Costa Rica's fungal trends: Insights from digitized specimens
Fungi are essential to tropical ecosystems but remain largely absent from conservation agendas. By analyzing over 78,000 fungal records from Costa Rica—a globally recognized biodiversity hotspot—this study reveals key patterns in fungal diversity, distribution, and seasonality.
Melissa Mardones +2 more
wiley +1 more source
The chicken gut virome: spatial structuring and extensive diversity of 19,778 viral populations. [PDF]
Sáenz JS +4 more
europepmc +1 more source
Rethinking intensification: Biodiversity‐inclusive management sustains coconut yields
Coconut palm expansion in West Africa will shape rural livelihoods and ecosystems. Our findings show that intensive practices reduce beneficial soil fungi and increase pathogens, threatening long‐term productivity. Lower‐intensity management that retains ground vegetation can sustain or boost yields while improving soil health.
Benjamin J. Roberts +10 more
wiley +1 more source
Metagenomic libraries data sets from the hypersaline benthic microbial mats of the Fraternidad Lagoon, Puerto Rico, using an indirect DNA extraction method. [PDF]
Nieves-Morales R +5 more
europepmc +1 more source
Abstract The bidirectional interplay between sleep and metabolic homeostasis is fundamental to physiological health. While the roles of glucose and lipid metabolism in sleep regulation have been extensively characterized, bile acids (BAs), which are traditionally viewed as digestive surfactants, are emerging as critical metabolic messengers with ...
Yu Jiang +4 more
wiley +1 more source
Integrating metagenomics and metatranscriptomics into <i>Orthoflavivirus</i> diagnosis: a transformative approach for clinical virology. [PDF]
Hosen ME, Horwood PF, Sarker S.
europepmc +1 more source
IBD is driven by a vicious cycle of dysbiosis, barrier dysfunction, and immune dysregulation. We developed an inulin–butyrate conjugate nanogel (IBN) that accumulates in inflamed colon and releases butyrate via microbial inulinase/esterase. The inulin shell remodels the microbiome, while localized butyrate strengthens barrier integrity and promotes ...
Nayoon Park +7 more
wiley +1 more source

