Butyrate ameliorates acute‐on‐chronic liver failure by regulating macrophage polarization
Multi‐omics profiling identifies progressive microbiota‐metabolism‐immunity axis dysfunction in acute‐on‐chronic liver failure (ACLF), characterized by gut dysbiosis, reduced butyrate production, intestinal barrier disruption, microbial translocation, and pro‐inflammatory macrophage polarization, thereby exacerbating hepatic inflammation and fibrosis ...
Jing Xiao +10 more
wiley +1 more source
Shotgun metagenomic sequence data from milk and fecal samples of dairy cattle in Thailand. [PDF]
Buddhasiri S +4 more
europepmc +1 more source
Lactobacillus derived small RNAs protect against Klebsiella pneumoniae infection
This study reveals that plant‐derived natural products confer protection against carbapenem‐resistant Klebsiella pneumoniae (CRKP) infection via remodeling the gut microbiota, with Lactobacillus identified as the core beneficial genus. Mechanistically, Lactobacillus murinus (L.
Tingting Xu +5 more
wiley +1 more source
Benchmarking of Reference-Based Tools for Strain-Level Resolution of Plant Microbiome. [PDF]
Sahil R, Jain M.
europepmc +1 more source
Multi‐omics approaches have revealed a cross‐species functional emergence phenomenon leading to emergent suppression of Fusarium wilt. We show that a three‑species consortium exhibits emergent suppression of Fusarium oxysporum f. sp. lycopersici (Fol) that is absent in single or pairwise cultures.
Lizhi Zhao +8 more
wiley +1 more source
metaIVP: an integrative metavirome focused metagenomic processing pipeline. [PDF]
Sahu K, Yao Q.
europepmc +1 more source
ABSTRACT The global incidence of intestinal diseases—including food allergy, inflammatory bowel disease (IBD), and colorectal cancer (CRC)—continues to escalate in parallel with the expansion of the “Western diet,” within which the high‐sugar diet (HSD) has emerged as a pivotal yet under‐recognized dietary driver.
Yuchen Wang +9 more
wiley +1 more source
A functionally selected <i>Acinetobacter</i> sp. phosphoethanolamine transferase gene from the goose fecal microbiome confers colistin resistance in <i>E. coli</i>. [PDF]
Bernate E, Shi Y, Franck E, Crofts TS.
europepmc +1 more source
Geriatric Regenerative Medicine: Mechanisms, Strategies, and Clinical Translation
The pathological drivers of aging—stem cell exhaustion, cellular senescence with SASP, and aged extracellular matrix—are precisely targeted by three corresponding mechanism‐based strategies: stem cell therapies (rejuvenation, regeneration, and replacement), senolytic/senomorphic agents (D + Q, fisetin, vaccines, and CAR‐T), and senescence‐targeting ...
Qiang Li +11 more
wiley +1 more source
VISTA: a classifier for metagenomic subspecies and community state typing of the vaginal microbiome. [PDF]
Holm JB +4 more
europepmc +1 more source

