Results 31 to 40 of about 133,465 (266)
Improving Pulmonary Infection Diagnosis with Metagenomic Next Generation Sequencing
Frontiers in Cellular and Infection Microbiology, 2021 Pulmonary infections are among the most common and important infectious diseases due to their high morbidity and mortality, especially in older and immunocompromised individuals.Yi-Yi Qian, Hong-Yu Wang, Yang Zhou, Hao-Cheng Zhang, Yi-Min Zhu, Xian Zhou, Yue Ying, Peng Cui, Hong-Long Wu, Hong-Long Wu, Wen-Hong Zhang, Wen-Hong Zhang, Wen-Hong Zhang, Wen-Hong Zhang, Jia-Lin Jin, Jing-Wen Ai +15 moredoaj +1 more sourceEBI metagenomics—a new resource for the analysis and archiving of metagenomic data [PDF]
, 2013 Metagenomics is a relatively recently established but rapidly expanding field that uses high-throughput next-generation sequencing technologies to characterize the microbial communities inhabiting different ecosystems (including oceans, lakes, soil ...Vaughan, Daniel, Mitchell, Alex, Field, Dawn, Gonzalez-Beltran, Alejandra, Scheremetjew, Maxim, McAnulla, Craig, Sansone, Susanna-Assunta, Sterk, Peter, Radhakrishnan, Rajesh, Hunter, Sarah, Leinonen, Rasko, Jones, Philip, Jones Philip, Denise, Hubert, Cochrane, Guy, Maslen, John, Oisel, Arnaud, Pesseat, Sebastien, Hubert, Denise, Corbett, Matthew, Fraser, Matthew, Rocca-Serra, Philippe, Hunter, Christopher, Michell, Alex, Maguire, Eamonn, Gift, Nuka, Nuka, Gift +26 morecore +2 more sourcesAn iterative workflow for mining the human intestinal metaproteome [PDF]
, 2011 Background Peptide spectrum matching (PSM) is the standard method in shotgun proteomics data analysis. It relies on the availability of an accurate and complete sample proteome that is used to make interpretation of the spectra feasible.Vos, W.M., de, Schaap, Peter, Willem M de Vos, Peter J Schaap, Boeren, S., Christian Beauvallet, Rooijers, Koos, Juste Catherine, Joël Doré, Doré Joël, Beauvallet, Christian, Been, M., de, Rooijers, K., de Been Mark, Schaap, P.J., Dore, Joel, Pilar Galan, Boeren Sjef, Beauvallet, C., Koos Rooijers, de Vos, W.M., Kolmeder, C., Schaap Peter J, Kolmeder, Carolin, Boeren, Sjef, de Vos, Willem M., de Been, Mark, Catherine Juste, Kolmeder Carolin, Galan, P., Doré, J., Rooijers Koos, Juste, C., Galan, Pilar, Mark de Been, Galan Pilar, Sjef Boeren, Beauvallet Christian, de Vos Willem M, de Vos, Willem, Juste, Catherine, Schaap, Peter J., de Been, M., Carolin Kolmeder +43 morecore +2 more sourcesIntegrated Metagenomic and Metabolomic Analyses of the Effect of Astragalus Polysaccharides on Alleviating High-Fat Diet–Induced Metabolic Disorders
Frontiers in Pharmacology, 2020 Most herbal polysaccharides possess multiple benefits against metabolic disorders, such as non-alcoholic fatty liver disease (NAFLD) and obesity. However, the underlying mechanisms are largely unknown.Ying Hong, Bingbing Li, Ningning Zheng, Gaosong Wu, Junli Ma, Xin Tao, Linlin Chen, Jing Zhong, Jing Zhong, Lili Sheng, Houkai Li +10 moredoaj +1 more sourceThe clinical application of metagenomic next-generation sequencing in infectious diseases at a tertiary hospital in China
Frontiers in Cellular and Infection Microbiology, 2022 BackgroundCompared with traditional diagnostic methods (TDMs), rapid diagnostic methods for infectious diseases (IDs) are urgently needed. Metagenomic next-generation sequencing (mNGS) has emerged as a promising diagnostic technology for clinical ...Chuwen Wang, Danying Yan, Jiajia Huang, Naibin Yang, Jiejun Shi, Shou Pan, Gaoqiang Lin, Ying Liu, Yingying Zhang, Xueyan Bian, Qifa Song, Guoqing Qian, Guoqing Qian +12 moredoaj +1 more sourceDesigning and implementing an assay for the detection of rare and divergent NRPS and PKS clones in European, Antarctic and Cuban soils [PDF]
, 2015 The ever increasing microbial resistome means there is an urgent need for new antibiotics. Metagenomics is an underexploited tool in the field of drug discovery. In this study we aimed to produce a new updated assay for the discovery of biosynthetic gene David A Pearce, Gregory C A Amos, Gregory C. A. Amos (799040), Leo Calvo-Bado (507757), Berry, Andrew E., Chiara Borsetto (799041), Andrew E Berry, Laskaris, Paris, Calvo-Bado, Leo, Paris Laskaris, Carlos Vallin (5665333), Berry, Andrew, Calvo-Bado, Leo A., David A. Pearce (189743), Leo Calvo-Bado, Elizabeth M H Wellington, Chiara Borsetto, Elizabeth M. H. Wellington (325617), Borsetto, Chiara, Kevin K Newsham, Amos, Gregory, Carlos Vallin, Paris Laskaris (325613), Andrew E. Berry (799043), Martin Krsek, Wellington, Elizabeth M. H., Martin Krsek (799042), Pearce, David, Pearce, David A., Kevin K. Newsham (352778), Vallin, Carlos, Krsek, Martin, Wellington, Elizabeth, Newsham, Kevin, Wellington, E. M. H., Amos, Gregory C. A., Newsham, Kevin K. +36 morecore +1 more sourcemetagenomic-cox1
, 2016 metagenomic ...Paula Arribas (725956), Carmelo Andújar (3269007), Alfried Vogler (3069711), Vogler, Alfried, Matthew Shepherd (3327735), Hopkins, Kevin, Kevin Hopkins (3327732), Shepherd, Matthew, Arribas, Paula, Andújar, Carmelo +9 morecore +1 more sourcePhylogenetic classification of short environmental DNA fragments [PDF]
, 2008 Krause L, Diaz NN, Goesmann A, et al. Phylogenetic classification of short environmental DNA fragments. Nucleic Acids Research. 2008;36(7):2230-2239.Metagenomics is providing striking insights into the ecology of microbial communities.Nattkemper, Tim Wilhelm ; https://orcid.org/, Krause, Lutz, Kelley, Scott, Stoye, Jens, Stoye, Jens ; https://orcid.org/, Diaz, Naryttza N., Goesmann, Alexander ; https://orcid.org/, Nattkemper, Tim W., Rohwer, Forest, Goesmann, Alexander, Edwards, Robert A. +10 morecore +1 more source