Results 51 to 60 of about 173,492 (295)

Pegivirus Detection in Cerebrospinal Fluid from Patients with Central Nervous System Infections of Unknown Etiology in Brazil by Viral Metagenomics

open access: yesMicroorganisms, 2023
Metagenomic next-generation sequencing (mNGS) methodology serves as an excellent supplement in cases where diagnosis is challenging to establish through conventional laboratory tests, and its usage is increasingly prevalent.
Rita de Cássia Compagnoli Carmona   +9 more
doaj   +1 more source

BIGMAC : breaking inaccurate genomes and merging assembled contigs for long read metagenomic assembly. [PDF]

open access: yes, 2016
BackgroundThe problem of de-novo assembly for metagenomes using only long reads is gaining attention. We study whether post-processing metagenomic assemblies with the original input long reads can result in quality improvement.
Clum, Alicia   +3 more
core   +2 more sources

A Bioinformatician's Guide to Metagenomics [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2008
SUMMARYAs random shotgun metagenomic projects proliferate and become the dominant source of publicly available sequence data, procedures for the best practices in their execution and analysis become increasingly important. Based on our experience at the Joint Genome Institute, we describe the chain of decisions accompanying a metagenomic project from ...
Kunin, V.   +4 more
openaire   +5 more sources

ASSESSMENT OF THE INTESTINAL MICROBIOTA IN ADULTS WITH EROSIVE ESOPHAGITIS

open access: yesArquivos de Gastroenterologia, 2021
BACKGROUND: The intestinal microbiota influences the appropriate function of the gastrointestinal tract. Intestinal dysbiosis may be associated with a higher risk of esophageal lesions, mainly due to changes in gastroesophageal motility patterns ...
Diego Cardoso BAIMA   +3 more
doaj   +1 more source

Impact of amoxicillin-clavulanate followed by autologous fecal microbiota transplantation on fecal microbiome structure and metabolic potential [PDF]

open access: yes, 2018
The spread of multidrug resistance among pathogenic organisms threatens the efficacy of antimicrobial treatment options. The human gut serves as a reservoir for many drug-resistant organisms and their resistance genes, and perturbation of the gut ...
Bulow, Christopher   +13 more
core   +2 more sources

Viral metagenomics [PDF]

open access: yesReviews in Medical Virology, 2007
AbstractCharacterisation of new viruses is often hindered by difficulties in amplifying them in cell culture, limited antigenic/serological cross‐reactivity or the lack of nucleic acid hybridisation to known viral sequences. Numerous molecular methods have been used to genetically characterise new viruses without prior in vitro replication or the use ...
openaire   +2 more sources

Host IP3R channels are dispensable for rotavirus Ca2+ signaling but critical for intercellular Ca2+ waves that prime uninfected cells for rapid virus spread

open access: yesmBio
Rotavirus is a leading cause of viral gastroenteritis. A hallmark of rotavirus infection is increased cytosolic Ca2+ caused by nonstructural protein 4 (NSP4).
Jacob L. Perry   +5 more
doaj   +1 more source

Explaining microbial population genomics through phage predation [PDF]

open access: yes, 2009
The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Alex Mira   +6 more
core   +2 more sources

The co‐occurrence of antibiotic resistance genes between dogs and their owners in families

open access: yesiMeta, 2022
The intimate relationship between humans and companion animals causes a unique and critical aspect of antimicrobial resistance in humans. However, a comprehensive analysis of antimicrobial resistance between companion animals and their owners is lacking.
Ruonan Zhao   +7 more
doaj   +1 more source

Discovery of two novel Torque Teno viruses in Callithrix penicillata provides insights on Anelloviridae diversification dynamics

open access: yesFrontiers in Microbiology, 2022
The development of high-throughput sequencing (HTS) technologies and metagenomics protocols deeply impacted the discovery of viral diversity.
Matheus Augusto Calvano Cosentino   +16 more
doaj   +1 more source

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