Results 81 to 90 of about 107,555 (273)

Elucidation of chemical profiles and molecular targets of Mondia whitei leave fractions bioactive as novel therapeutics: an in vitro and in silico assay

open access: yesJournal of Genetic Engineering and Biotechnology, 2022
Background Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and possible molecular targets.
Hope Onohuean   +7 more
doaj   +1 more source

Commet: comparing and combining multiple metagenomic datasets [PDF]

open access: yesarXiv, 2015
Metagenomics offers a way to analyze biotopes at the genomic level and to reach functional and taxonomical conclusions. The bio-analyzes of large metagenomic projects face critical limitations: complex metagenomes cannot be assembled and the taxonomical or functional annotations are much smaller than the real biological diversity.
arxiv  

Towards complete representation of bacterial contents in metagenomic samples [PDF]

open access: yesarXiv, 2022
Background: In the metagenome assembly of a microbiome community, we may think abundant species would be easier to assemble due to their deeper coverage. However, this conjucture is rarely tested. We often do not know how many abundant species we are missing and do not have an approach to recover these species.
arxiv  

Metagenomic Analysis of Silage [PDF]

open access: yesJournal of Visualized Experiments, 2017
Metagenomics is defined as the direct analysis of deoxyribonucleic acid (DNA) purified from environmental samples and enables taxonomic identification of the microbial communities present within them. Two main metagenomic approaches exist; sequencing the 16S rRNA gene coding region, which exhibits sufficient variation between taxa for identification ...
John Love   +4 more
openaire   +3 more sources

Spaced seeds improve k-mer-based metagenomic classification [PDF]

open access: yes, 2015
Metagenomics is a powerful approach to study genetic content of environmental samples that has been strongly promoted by NGS technologies. To cope with massive data involved in modern metagenomic projects, recent tools [4, 39] rely on the analysis of k ...
Brinda, Karel   +2 more
core   +2 more sources

Translational metagenomics [PDF]

open access: yesJournal of Translational Medicine, 2021
Selvasankar Murugesan   +1 more
openaire   +3 more sources

CLMB: deep contrastive learning for robust metagenomic binning [PDF]

open access: yesarXiv, 2021
The reconstruction of microbial genomes from large metagenomic datasets is a critical procedure for finding uncultivated microbial populations and defining their microbial functional roles. To achieve that, we need to perform metagenomic binning, clustering the assembled contigs into draft genomes. Despite the existing computational tools, most of them
arxiv  

Promises and Prospects of Microbiome Studies [PDF]

open access: yes, 2015
Since Anthony van Leeuwenhoek, first microscopic observations of the unseen microbiota and the more recent realization that little of the microbes in the biosphere are known, humans have developed a deep curiosity to fully understand the inner workings ...
Izard, Jacques, Rivera, Maria C.
core   +1 more source

Accelerating exhaustive pairwise metagenomic comparisons [PDF]

open access: yes, 2017
In this manuscript, we present an optimized and parallel version of our previous work IMSAME, an exhaustive gapped aligner for the pairwise and accurate comparison of metagenomes. Parallelization strategies are applied to take advantage of
A Alyass   +13 more
core   +2 more sources

Association of Flavonifractor plautii, a Flavonoid-Degrading Bacterium, with the Gut Microbiome of Colorectal Cancer Patients in India

open access: yesmSystems, 2019
Recently, dysbiosis in the human gut microbiome and shifts in the relative abundances of several bacterial species have been recognized as important factors in colorectal cancer (CRC).
Ankit Gupta   +12 more
doaj   +3 more sources

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