Clinical metagenomics assessments improve diagnosis and outcomes in community-acquired pneumonia
Background Identifying the causes of community-acquired pneumonia (CAP) is challenging due to the disease’s complex etiology and the limitations of traditional microbiological diagnostic methods.
F. Xie +8 more
semanticscholar +1 more source
The Gut Resistome Atlas in Preterm Infants Enables Prediction of Necrotizing Enterocolitis Onset
The gut resistome of preterm infants and its clinical relevance remain poorly understood. This study performs in‐depth integrative analyses of 5,684 gut metagenomes from preterm infants, uncovering distinct features that diverge from term infants. Notably, the gut resistome of preterm infants converges 9 days before necrotizing enterocolitis onset ...
Shuqin Zeng +22 more
wiley +1 more source
Longitudinal study of the scalp microbiome suggests coconut oil to enrich healthy scalp commensals
Dandruff is a recurrent chronic scalp disorder, affecting majority of the population worldwide. Recently a metagenomic study of the Indian scalp microbiome described an imperative role of bacterial commensals in providing essential vitamins and amino ...
Rituja Saxena +7 more
doaj +1 more source
Characterization of the Gut Microbiome Using 16S or Shotgun Metagenomics
The advent of next generation sequencing (NGS) has enabled investigations of the gut microbiome with unprecedented resolution and throughput. This has stimulated the development of sophisticated bioinformatics tools to analyze the massive amounts of data
J. Jovel +10 more
semanticscholar +1 more source
Deconvolute individual genomes from metagenome sequences through short read clustering. [PDF]
Metagenome assembly from short next-generation sequencing data is a challenging process due to its large scale and computational complexity. Clustering short reads by species before assembly offers a unique opportunity for parallel downstream assembly of
Deng, Li +5 more
core
Differential Functional Constraints Cause Strain-Level Endemism in Polynucleobacter Populations. [PDF]
The adaptation of bacterial lineages to local environmental conditions creates the potential for broader genotypic diversity within a species, which can enable a species to dominate across ecological gradients because of niche flexibility.
Geeta Rijal +8 more
core +2 more sources
The 2500‐year‐old Mulberry‐dyke and Fish‐pond agricultural heritage system reveals how interconnected habitats foster microbial diversity. Multi‐habitat landscapes enhance microbial diversity through cross‐habitat dispersal and adaptive trait convergence. Globally, regions with diverse habitats support a greater diversity of soil microbiomes.
Jintao He +8 more
wiley +1 more source
Diversity of dsDNA Viruses in a South African Hot Spring Assessed by Metagenomics and Microscopy
The current view of virus diversity in terrestrial hot springs is limited to a few sampling sites. To expand our current understanding of hot spring viral community diversity, this study aimed to investigate the first African hot spring (Brandvlei hot ...
Olivier Zablocki +3 more
doaj +1 more source
Virome research is a rapidly growing area in the microbiome field that is increasingly associated with human diseases, such as inflammatory bowel disease (IBD).
Daan Jansen, Jelle Matthijnssens
doaj +1 more source
Time series genome-centric analysis unveils bacterial response to operational disturbance in activated sludge [PDF]
Understanding ecosystem response to disturbances and identifying the most critical traits for the maintenance of ecosystem functioning are important goals for microbial community ecology.
Erijman, Leonardo +4 more
core +1 more source

