Results 11 to 20 of about 2,133,478 (281)
Developing drugs targeting transition metal homeostasis [PDF]
Current Opinion in Chemical Biology, 2017 Metal dyshomeostasis is involved in the pathogenesis and progression of diseases including cancer and neurodegenerative diseases. Metal chelators and ionophores are well known modulators of transition metal homeostasis, and a number of these molecules are in clinical trials. Metal-binding compounds are not the only drugs capable of targeting transition
Weekley, CM, He, C
openaire +5 more sources
Osteoclast responses to metal ions [PDF]
, 2009 Màster Oficial en Enginyeria BiomèdicaCentral model of the study will be the osteoclast culture on dentin. Osteoclast development from monocytes will be followed biochemically and histologically.
Prehn Gallo, Ricardo
core +6 more sources
Battle for Metals: Regulatory RNAs at the Front Line
Frontiers in Cellular and Infection Microbiology, 2022 Metal such as iron, zinc, manganese, and nickel are essential elements for bacteria. These nutrients are required in crucial structural and catalytic roles in biological processes, including precursor biosynthesis, DNA replication, transcription ...
Mathilde Charbonnier +4 more
doaj +1 more source
Acta Biochimica et Biophysica Sinica, 2023 MgtE is a Mg 2+-selective channel regulated by the intracellular Mg 2+ concentration. MgtE family proteins are highly conserved in all domains of life and contribute to cellular Mg 2 ...
Wang Mengqi +4 more
doaj +1 more source
Regulation of Bacterial Manganese Homeostasis and Usage During Stress Responses and Pathogenesis
Frontiers in Molecular Biosciences, 2022 Manganese (Mn) plays a multifaceted role in the survival of pathogenic and symbiotic bacteria in eukaryotic hosts, and it is also important for free-living bacteria to grow in stressful environments.
Julia E. Martin, Lauren S. Waters
doaj +1 more source
Gold uptake and tolerance in Arabidopsis [PDF]
, 2011 Gold is a precious metal with a variety of industrial uses. The gold mining process is often incomplete, and discarded mine tailings contain quantities of gold uneconomical for conventional extraction.
Taylor, Andrew
core +6 more sources
Frontiers in Plant Science, 2022 Transporters belonging to the natural resistance-associated macrophage protein (Nramp) family play important roles in metal uptake and homeostasis. Although Nramp members have been functionally characterized in plants, the role of Nramp in the important ...
Xiaoyan Zou +11 more
doaj +1 more source
Iron uptake, signaling, and sensing in plants
Plant Communications, 2022 Iron (Fe) is an essential micronutrient that affects the growth and development of plants because it participates as a cofactor in numerous physiological and biochemical reactions. As a transition metal, Fe is redox active. Fe often exists in soil in the
Gang Liang
doaj +1 more source
The Role of Low-Molecular-Weight Organic Acids in Metal Homeostasis in Plants [PDF]
International Journal of Molecular SciencesIlya Seregin, Anna Kozhevnikova
exaly +2 more sources
Metal homeostasis and resistance in bacteria [PDF]
Nature Reviews Microbiology, 2017 Metal ions are essential for many reactions, but excess metals can be toxic. In bacteria, metal limitation activates pathways that are involved in the import and mobilization of metals, whereas excess metals induce efflux and storage. In this Review, we highlight recent insights into metal homeostasis, including protein-based and RNA-based sensors that
Pete, Chandrangsu +2 more
openaire +2 more sources