Results 181 to 190 of about 7,597 (252)

The novel ADAMs-like microbial metalloendopeptidase

Russian Journal of Bioorganic Chemistry, 2012
Heterologous gene expression of extracellular minor metalloendopeptidase of Bacillus pumilus 3-19 in protease-deficient B. subtilis strain has been studied. The fraction of enzyme in total pool of B. pumilus 3-19 secreted proteases composes less than 8%.
Natalia Rudakova
exaly   +5 more sources

Evaluation of Antidiabetic Activities of Casein Hydrolysates by a Bacillus Metalloendopeptidase

International Journal of Peptide Research and Therapeutics, 2020
Sam Al-Dalali, Xiao Zhao, 智杰 杨
exaly   +2 more sources

Degradation of bradykinin by a metalloendopeptidase from Streptococcus pyogenes

Journal of Oral Biosciences, 2016
Streptococcus pyogenes secretes streptococcal pyrogenic exotoxin B (SpeB), which cleaves kininogen to liberate bradykinin. In addition, this bacterium also has cell-associated bradykinin-degrading activity. Here, we characterized the bradykinin-degrading enzyme produced by S.
Yoichi, Miyamoto, Takaaki, Akaike, Shigetada, Kawabata, Teruo, Akuta, Chiho, Taruki, Jun, Yoshitake, Shigeyuki, Hamada, Fusao, Ota, Hideo, Igarashi, Kentaro, Yoshimura, Ryutaro, Kamijo, Hiroshi, Maeda   +11 more
openaire   +3 more sources

Structure modeling of a metalloendopeptidase from Corynebacterium pseudotuberculosis

Computers in Biology and Medicine, 2012
Metalloendopeptidases are zinc-dependent hydrolases enzymes with many different roles in biological systems, ranging from remodeling conjunctive tissue to removing signaling sequences from nascent proteins. Here, we describe the three-dimensional structure of the metalloendopeptidase from Corynebacterium pseudotuberculosis generated by homology ...
Artur Silva, Jerônimo Lameira
exaly   +3 more sources

Efficiency of Recombinant Strains as Producers of Metalloendopeptidase from Bacillus pumilis 3-19

Microbiology
Natalia Rudakova, Margarita R Sharipova
exaly   +2 more sources

Toxoid construction of AsaP1, a lethal toxic aspzincin metalloendopeptidase of Aeromonas salmonicida subsp. achromogenes, and studies of its activity and processing

Veterinary Microbiology, 2013
Uwe T Bornscheuer, Winfried Hinrichs, Bjarnheidur K Gudmundsdottir   +2 more
exaly   +2 more sources

Salviolone protects against high glucose‐induced proliferation, oxidative stress, inflammation, and fibrosis of human renal mesangial cells by upregulating membrane metalloendopeptidase expression

Chemical Biology and Drug Design, 2022
As one of complications of diabetes mellitus, diabetic nephropathy is related to renal dysfunction. Membrane metalloendopeptidase (MME) is associated with the pathogenesis of diabetic nephropathy and exerts a protective function in high glucose (HG ...
Xichao Wang, R. Song, Zhuo Li
semanticscholar   +1 more source

Insights on the inhibition properties of Jatromollistatin (a cyclic heptapeptide) against Crotalus adamanteus metalloendopeptidase using molecular docking analysis

Journal of Molecular Recognition, 2022
Jatropha mollissima is endemic to Brazil and is used for traditional medicinal purposes, including the treatment of snakebite. In this study, latex obtained from this plant was fractioned using reversed‐phase chromatography, and the fractions were then ...
T. L. Jucá, M. Ramos, E. Cilli, A. E. V. Neto, S. Mackessy, A. Monteiro-Moreira   +5 more
semanticscholar   +1 more source

Peptidyl-Lys metalloendopeptidase (Lys-N) purified from dry fruit of Grifola frondosa demonstrates "mirror" digestion property with lysyl endopeptidase (Lys-C).

Rapid Communications in Mass Spectrometry, 2020
Lys-N, also known as lysine-specific metalloendopeptidase, functions as the "sister" enzyme of lysyl endopeptidase (Lys-C) in proteomic research. Its digestion specificity at the N-terminal lysine residue makes it a very useful tool in proteomics ...
Mingzhi Zhao, Bingbing Hao, Honghao Li, M. Cai, Jingjing Xie, Hongyu Liu, M. Tan, Linhui Zhai, Qun Yu   +8 more
semanticscholar   +1 more source

The interaction between the natural metalloendopeptidase inhibitor BJ46a and its target toxin jararhagin analyzed by structural mass spectrometry and molecular modeling.

Journal of Proteomics, 2020
Snakebite envenoming affects millions of people worldwide, being officially considered a neglected tropical disease by the World Health Organization. The antivenom is effective in neutralizing the systemic effects of envenomation, but local effects are ...
Viviane A. Bastos, F. Gomes-Neto, S. L. Rocha, A. Teixeira-Ferreira, J. Perales, A. Neves-Ferreira, R. H. Valente   +6 more
semanticscholar   +1 more source