Results 91 to 100 of about 14,646 (214)

FGF21 Protects Against Hypoxia Injury Through Inducing HSP72 in Cerebral Microvascular Endothelial Cells

Frontiers in Pharmacology, 2019
Background: Fibroblast growth factor 21 (FGF21), a member of a family of atypical FGFs, functions as cytokine to control endocrinology and metabolism. Recently, the roles of FGF21 in cardio-cerebral-vascular diseases have been gradually uncovered. In the
Hao-Wei Wang, Xin Jiang, Yu Zhang, Jian Wang, Jian Xie, Yong-Qiang Wang, Yong-Hua Li   +6 more
doaj   +1 more source

Metal‐Directed Self‐Assembly in a Beta‐Sheet Miniprotein Scaffold

European Journal of Inorganic Chemistry, Volume 29, Issue 7, 2 March 2026.
A rationally engineered miniprotein, V14C, which is based on the beta β‐sheet Foldon domain, self‐assembles via a metal‐binding site to form well‐defined oligomers in the presence of Zn2+, Hg2+, and Cd2+. This modular design expands the toolbox for creating custom metalloproteins, enabling studies of metal–protein interactions for biochemical functions
Chandan Muni Reddy, Marcos R. Conde González, Jürgen H. Gross, Franziska Thomas   +3 more
wiley   +1 more source

Matrix Metalloproteinase-9 () polymorphisms in patients with cutaneous malignant melanoma [PDF]

, 2007
Background Cutaneous Malignant Melanoma causes over 75% of skin cancer-related deaths, and it is clear that many factors may contribute to the outcome.
Javier Cotignola, Boris Reva, Nandita Mitra, Nicole Ishill, Shaokun Chuai, Ami Patel, Shivang Shah, Gretchen Vanderbeek, Daniel Coit, Klaus Busam, Allan Halpern, Alan Houghton, Chris Sander, Marianne Berwick, Irene Orlow, A Jemal, LJ McCawley, S Pasco, SC Liu, H Islekel, W Zhao, YG Shellman, JJ van den Oord, UB Hofmann, MD Corte, J Nikkola, S Zucker, K Jung, GS Makowski, PE Van den Steen, RC Millikan, J Gough, CD Bennett, M Ronaghi, M Franchina, PJ Oefner, I Orlow, PD Sasieni, EL Kaplan, L Excoffier, JH Zhao, DJ Schaid, DG Peters, S Shimajiri, PE Ferrand, B Bodey, J Nikkola, UB Hofmann, B Zhang, F Grieu, S Matsumura, E Chicoine, EM Schnaeker, Y Awakura   +53 more
core   +1 more source

Broadening the Workflow for Synchrotron‐Based X‐Ray Fluorescence and X‐Ray Absorption Spectroscopy Imaging of Low‐Abundance Cellular Metals

Chemistry–Methods, Volume 6, Issue 3, March 2026.
We present an accessible plunge‐freezing and freeze‐drying workflow for preparing adherent mammalian cells for synchrotron‐based nanofocused X‐ray fluorescence (XRF) microscopy and X‐ray absorption spectroscopy (XAS), enabling sub‐micron mapping of metal distribution and chemical speciation.
Joaquin Tamargo‐Azpilicueta, Rafael L. Giner‐Arroyo, Pablo Rivero‐García, Sofia Diaz‐Moreno, Miguel A. Gomez‐Gonzalez, Abbey Telfer, Michelangelo Campanella, Miguel A. De la Rosa, Irene Díaz‐Moreno   +8 more
wiley   +1 more source

Metal-substituted protein MRI contrast agents engineered for enhanced relaxivity and ligand sensitivity [PDF]

, 2010
Engineered metalloproteins constitute a flexible new class of analyte-sensitive molecular imaging agents detectable by magnetic resonance imaging (MRI), but their contrast effects are generally weaker than synthetic agents.
Alan Jasanoff, Brash A. R., Brugna M., Eric Brustad, Frances H. Arnold, Gelb M. H., Gupta R., Jasanoff A., Lelyveld V. S., Li Y., Makris T. M., Ogawa S., Richard-Fogal C. L., Shapiro M. G., Solomon I., Sun P. Z., Varnado C. L., Victor S. Lelyveld, Villarreal D. M., Vymazal J., Winter M. B., Woodward J. J.   +21 more
core   +2 more sources

A Comprehensive Review on the Significance of Antioxidants and Their Influence on Biopolymer Packaging Films: Recent Advances and Challenges

Food Frontiers, Volume 7, Issue 2, March 2026.
Influence of antioxidants‐loaded biopolymer films on food security and extended shelf life. ABSTRACT Autooxidation is a significant cause of quality deterioration in food systems, leading to nutrient loss, off‐flavor formation, textural changes, and overall spoilage.
Sai Kumar Tammina, Rambabu Krishnamoorthy, Arshied Manzoor, Ruchir Priyadarshi, Kandi Sridhar, Fawzi Banat   +5 more
wiley   +1 more source

The expression of the gene for Azurin from Alcaligenes denitrificans in E. coli : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Biochemistry at Massey University [PDF]

, 1994
Azurin is a protein which funtions in electron transport and has been found to bind copper when it is expressed in its native bacterial host. In this thesis the azurin from Alcaligenes denitrificans was used.
Bateson, Joseph Anthony
core  

Marked changes in electron transport through the blue copper protein azurin in the solid state upon deuteration

, 2012
Measuring electron transport (ETp) across proteins in the solid-state offers a way to study electron transfer (ET) mechanism(s) that minimizes solvation effects on the process.
Alessandrini, Antonello, Battistuzzi, Beratan, D. Cahen, Davis, Gray, Groeneveld, Hammes-Schiffer, I. Pecht, Kovacs, M. Sheves, Marcus, Marshall, MEI, N. Amdursky, Regan, Ringe, Ron, Rosen, Sepunaru, Sepunaru, Teeter, Whitmire, Zhao   +24 more
core   +1 more source

(Eta6-arene) ruthenium(II) complexes and metallo-papain hybrid as Lewis acid catalysts of Diels-Alder reaction in water. [PDF]

, 2010
International audienceCovalent embedding of a (eta(6)-arene) ruthenium(II) complex into the protein papain gives rise to a metalloenzyme displaying a catalytic efficiency for a Lewis acid-mediated catalysed Diels-Alder reaction enhanced by two orders of ...
Cordier, Stéphane, de Montigny, Frédéric, Fosse, Céline, Haquette, Pierre, Jaouen, Gérard, Martel, Annie, Roisnel, Thierry, Salmain, Michèle, Talbi, Barisa   +8 more
core   +3 more sources

Global Burden of Lead Exposure: Integrating Epidemiology, Molecular Mechanisms, and Mitigation Approaches

Health Science Reports, Volume 9, Issue 3, March 2026.
ABSTRACT Background Lead is a nonessential, toxic heavy metal that causes widespread environmental contamination, affecting humans, animals, plants, and ecosystems. Globally, an estimated 800 million children have blood lead levels (BLLs) above 5 µg/dL.
Gudisa Bereda
wiley   +1 more source