Results 151 to 160 of about 181,236 (248)

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

The effects of cytokines on metalloproteinase inhibitors (TIMP) and collagenase production by human chondrocytes and TIMP production by synovial cells and endothelial cells

, 1993
M Shingu, Yutaka Nagai, T. Isayama, T. Naono, Masashi Nobunaga, Yoko Nagai   +5 more
openalex   +2 more sources

Matrix Metalloproteinases in the Normal Human Central Nervous System, Microglial Nodules, and Multiple Sclerosis Lesions [PDF]

, 1996
Atsuko Maeda, Raymond A. Sobel
openalex   +1 more source

Sound‐Based Assembly of Magnetically Actuated Soft Robots Toward Enhanced Release of Extracellular Vesicles

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Magnetic soft robots offer promise in biomedicine due to their wireless actuation and rapid response, but current fabrication methods are complex and have limited cellular compatibility. A new, contactless bioassembly strategy using hydrodynamic instabilities is introduced, enabling customizable, centimeter‐scale robots.
Wei Gao, Riccardo Tognato, Micaela Natta, Elena Della Bella, Alessandro Cianciosi, Tiziano Serra   +5 more
wiley   +1 more source

Protein Biomarkers in Venous Leg Ulcer Fluid: A Systematic Review. [PDF]

Int Wound J
Reddi R, Tan M, Davies AH, Onida S.
europepmc   +1 more source

Regulated expression of matrix metalloproteinases and TIMP in nephrogenesis [PDF]

, 1998
Diana C. Tanney, Lili Feng, Alan S. Pollock, David H. Lovett   +3 more
openalex   +1 more source

Astaxanthin ameliorates benzalkonium chloride–induced dry eye disease through suppressing inflammation and oxidative stress via Keap1‐Nrf2/HO‐1 signaling pathways

Animal Models and Experimental Medicine, EarlyView.
The flowchart of this research. Abstract Background Dry eye disease (DED) predominantly results from elevated tear film osmolarity, which can not only cause ocular inconvenience but may lead to visual impairments, severely compromising patient well‐being and exerting substantial economic burdens as well.
Ziyu Liu, Yaqiong Li, Jiayu Bao, Siyuan Li, Ya Wen, Peng Zhang, Jun Feng, Yinghui Wang, Lei Tian, Ying Jie   +9 more
wiley   +1 more source

Matrix metalloproteinase-7 is dispensable in a mouse model of sepsis-induced acute lung injury. [PDF]

PLoS One
Baer B, Lin J, Schaaf KR, Ware LB, Shaver CM, Bastarache JA.   +5 more
europepmc   +1 more source

Transplanting neural stem cells overexpressing miRNA‐21 can promote neural recovery after cerebral hemorrhage through the SOX2/LIN28‐let‐7 signaling pathway

Animal Models and Experimental Medicine, EarlyView.
Abstract Background Intracerebral hemorrhage (ICH) remains a devastating neurological disorder with limited therapeutic options. Neural stem cell (NSC)‐based therapies have emerged as a potential regenerative approach, yet the molecular mechanisms regulating NSC behavior require further elucidation.
Wei Dai, Yongxia Li, Jiarui Du, Gang Shen, Meimei Fan, Zuopeng Su, Fulin Xu, Fang Yuan   +7 more
wiley   +1 more source

Relationships between MMP-2, MMP-9, and ADAMDEC1 serum and tissue levels in patients with colorectal cancer. [PDF]

Ann Coloproctol
Mozooni Z, Amiri KK, Golestani N, Shahmohammadi A, Minaeian S, Bahadorizadeh L.   +5 more
europepmc   +1 more source