Results 181 to 190 of about 181,236 (248)

[Retracted] Effect of Etiasa on the expression of matrix metalloproteinase‑2 and tumor necrosis factor‑α in a rat model of ulcerative colitis. [PDF]

Mol Med Rep
Mao JW, Tang HY, Tan XY, Wang YD.
europepmc   +1 more source

Extracellular Vesicles in Calcium Oxalate Nephrolithiasis: Emerging Biomarkers and Therapeutic Potential

Advanced NanoBiomed Research, EarlyView.
Kidney stones cause significant pain and healthcare costs. Current prediction, diagnosis, and treatment options are limited. Extracellular vesicles (EVs), rich in proteins, lipids, and nucleic acids, offer a promising solution. This review explores the roles of EVs in kidney stone management, highlighting their potential as biomarkers and therapeutic ...
Wang Zhu, Xu Changzhi, Deng Qiong, Liang Hui   +3 more
wiley   +1 more source

The Wnt/β-Catenin Inhibitor HC-1 Suppresses Liver Fibrosis by Inhibiting Activated Hepatic Stellate Cells and Inducing Matrix Metalloproteinase-1. [PDF]

Yonago Acta Med
Hatakeyama D, Itaba N, Shimizu H, Morimoto M, Shiota G.   +4 more
europepmc   +1 more source

Regulation of matrix metalloproteinase-2 (MMP-2) by hepatocyte growth factor/scatter factor (HGF/SF) in human glioma cells: HGF/SF enhances MMP-2 expression and activation accompanying up-regulation of membrane type-1 MMP [PDF]

, 1999
Ryouichi Hamasuna, Hiroaki Kataoka, Takuzou Moriyama, Hiroshi Itoh, Motoharu Seiki, Masashi Koono   +5 more
openalex   +1 more source

Exosomes in Intervertebral Disc Regeneration: Roles, Opportunities, and Challenges

Advanced NanoBiomed Research, EarlyView.
Factors of Intervertebral Disc Degeneration Extracellular Matrix (ECM) Exosomes and Intervertebral Disc Degeneration (IVDD) Exosome‐Mediated Therapy for IVDD of Different Cell Sources Application of Engineered Exosomes in IVDD Clinical Application of Exosomes in IVDD Treatment Conclusion and Future Perspectives. Intervertebral disc degeneration (IVDD),
Xianglong Zhou, Tianyi Xia, Jiheng Xiao, Jianhui Xiang, Hanhong Fang, Haoran Zhou, Yiqiang Hu, Liming Xiong   +7 more
wiley   +1 more source

Huangqi Decoction reduces liver fibrosis in rats by modulating PI3K/Akt/mTOR signaling and promoting autophagy. [PDF]

Biomol Biomed
Mai J, Hou T, Shi J, Cheng Y.
europepmc   +1 more source

A Sequence-selective Single-strand DNA-binding Protein Regulates Basal Transcription of the Murine Tissue Inhibitor of Metalloproteinases-1 (Timp-1) Gene [PDF]

, 1999
Blaine Phillips, Renuka Sharma, Pamela A. Leco, Dylan R. Edwards   +3 more
openalex   +1 more source

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

Angewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Retraction Note: The role of cyclooxygenase-2, interleukin-1β and fibroblast growth factor-2 in the activation of matrix metalloproteinase-1 in sheared-chondrocytes and articular cartilage. [PDF]

Sci Rep
Guan PP, Guo JW, XinYu, Wang Y, Wang T, Konstantopoulos K, Wang ZY, Wang P.   +7 more
europepmc   +1 more source

Simvastatin‐Release Photocurable Hydrogel With Microsphere Delivery System for Improved Dental Applications

Journal of Applied Polymer Science, EarlyView.
ABSTRACT The development of multifunctional injectable biomaterials that serve as frameworks for tissue neo‐deposition and promote dentin regeneration through resident dental pulp cells represents an innovative approach in regenerative dentistry. This study presents an injectable system based on a photocrosslinkable hydrogel, functionalized with a drug
Erika S. Bronze‐Uhle, Isabela S. P. Silva, Ester A. F. Bordini, Vitor T. Stuani, Camila C. S. B. Melo, Priscila T. A. de Toledo, Ligia E. Correa, Daniel Rinaldo, Carlos A. de Souza‐Costa, Paulo N. Lisboa‐Filho, Diana G. Soares   +10 more
wiley   +1 more source